Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Roberto PARISE-FILHO"'
Autor:
Maurício T. Tavares, Arne Krüger, Sun L. Rei Yan, Karoline B. Waitman, Vinícius M. Gomes, Daffiny Sumam de Oliveira, Franciarli Paz, Sebastian Hilscher, Mike Schutkowski, Wolfgang Sippl, Claudia Ruiz, Mônica F. Z. J. Toledo, Neuza M. A. Hassimotto, João A. Machado-Neto, Antti Poso, Michael D. Cameron, Thomas D. Bannister, Giuseppe Palmisano, Carsten Wrenger, Thales Kronenberger, Roberto Parise-Filho
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-20 (2023)
Abstract We report a series of 1,3-diphenylureido hydroxamate HDAC inhibitors evaluated against sensitive and drug-resistant P. falciparum strains. Compounds 8a–d show potent antiplasmodial activity, indicating that a phenyl spacer allows improved
Externí odkaz:
https://doaj.org/article/661e63afc62b4a918f5086fa3323ea43
Autor:
Maurício Temotheo TAVARES, Luiza Silva FERREIRA, Marina Candido PRIMI, Jeanine GIAROLLA, Roberto PARISE-FILHO
Publikováno v:
Infarma: Pharmaceutical Sciences, Vol 30, Iss 3, Pp 168-177 (2018)
A internacionalização do ensino superior foi incorporada às diretrizes das universidades brasileiras e estágios no exterior são bons exemplos desta medida. Nos últimos anos, a procura por estágios internacionais tem aumentado, porém, a litera
Externí odkaz:
https://doaj.org/article/c24edfd5f1284124a4a15defedb9cb3d
Autor:
Catarina Rosado, Viviane Kaori Tokunaga, Rafael Sauce, Camila Areias de Oliveira, Fernanda Daud Sarruf, Roberto Parise-Filho, Elisabete Maurício, Tânia Santos de Almeida, Maria Valéria Robles Velasco, André Rolim Baby
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
The excessive exposure to ultraviolet (UV) radiation is the main cause of skin cancer, the most commonly diagnosed cancer in the world. In this context, the development of innovative and more effective sunscreens, with bioactive compounds like caffei
Externí odkaz:
https://doaj.org/article/4253eff1512a4b718048a47705b7a38c
Autor:
Micael Rodrigues Cunha, Maurício Temotheo Tavares, Thais Batista Fernandes, Roberto Parise-Filho
Publikováno v:
Molecules, Vol 26, Iss 6, p 1521 (2021)
Piper, Capsicum, and Pimenta are the main genera of peppers consumed worldwide. The traditional use of peppers by either ancient civilizations or modern societies has raised interest in their biological applications, including cytotoxic and antiproli
Externí odkaz:
https://doaj.org/article/a72d8e63def04251883a34134e3d7100
Autor:
Maurício Temotheo Tavares, Marina Candido Primi, Camila Felix de Carvalho, Michelle Carneiro Polli, Roberto Parise-Filho
Publikováno v:
Química Nova, Vol 39, Iss 4, Pp 502-506 (2016)
Cholesterol is a lipid which in high concentration can be an important risk factor for coronary diseases and atherosclerotic lesions. This lipid presents an endogenous biosynthesis that involves several steps; one of them is modulated by the enzyme 3
Externí odkaz:
https://doaj.org/article/292b7055b54b435abd76a90c1f07d66c
Autor:
Maurício Temotheo Tavares, Marina Candido Primi, Michelle Carneiro Polli, Elizabeth Igne Ferreira, Roberto Parise-Filho
Publikováno v:
Química Nova, Vol 38, Iss 8, Pp 1117-1124 (2015)
Teaching classes and events regarding the molecular aspects of drug-receptor interactions is not an easy task. The ligand stereochemistry and the spatial arrangement of the macromolecular targets highly increase the complexity of the process. In this
Externí odkaz:
https://doaj.org/article/21300c14ef29497792094341c06842d3
Autor:
Otávio Augusto Chaves, Maurício Temotheo Tavares, Micael Rodrigues Cunha, Roberto Parise-Filho, Carlos Maurício R. Sant’Anna, José Carlos Netto-Ferreira
Publikováno v:
Biomolecules, Vol 8, Iss 3, p 78 (2018)
The interaction between the main carrier of endogenous and exogenous compounds in the human bloodstream (human serum albumin, HSA) and a potential anticancer compound (the capsaicin analogue RPF101) was investigated by spectroscopic techniques (circu
Externí odkaz:
https://doaj.org/article/d7489665ccd44e9988256e2aad039f86
Autor:
Elisa Souza Vaz, Sandra Valeria Vassiliades, Jeanine Giarolla, Michelle Carneiro Polli, Roberto Parise-Filho
Publikováno v:
European Journal of Clinical Pharmacology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4279e7534899174e88559422761cf216
https://doi.org/10.1007/s00228-023-03486-4
https://doi.org/10.1007/s00228-023-03486-4
Publikováno v:
Mini-Reviews in Medicinal Chemistry. 23
Abstract: The folate metabolic cycle is an important biochemical process for the maintenance of cellular homeostasis, and is a widely studied pathway of cellular replication control in all organisms. In microorganisms such as M. tuberculosis (Mtb), f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75e84a29c95dfd41b6419a439e6950d3
https://doi.org/10.2174/1389557523666230206163154
https://doi.org/10.2174/1389557523666230206163154