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pro vyhledávání: '"Roberto Mastio"'
Autor:
Sophie Manner, Ulf Ellervik, Emil Tykesson, Roberto Mastio, Zackarias Söderlund, Gunilla Westergren-Thorsson, Daniel Willén
Publikováno v:
Bioconjugate Chemistry
We present a xylosylated naphthoxyloside carrying a terminal azide functionality that can be used for conjugation using click chemistry. We show that this naphthoxyloside serves as a substrate for β4GalT7 and induces the formation of soluble glycosa
Autor:
Sophie Manner, Ulf Ellervik, Zackarias Söderlund, Gunilla Westergren-Thorsson, Daniel Willén, Emil Tykesson, Roberto Mastio
Publikováno v:
RSC advances. 11(60)
Five novel xylosides tagged with the fluorescent probe Pacific Blue™ were synthesized and found to act as substrates for β4GalT7, a bottleneck enzyme in the biosynthetic pathways leading to glycosaminoglycans. By confocal microscopy of A549 cells,