A bilateral cervical contusion injury model in mice: Assessment of gripping strength as a measure of forelimb motor function

Autor: Oswald Steward, Roberto M. Aguilar

Publikováno v: Experimental Neurology. 221:38-53

Here, we describe a bilateral cervical contusion model for mice. Adult female mice received graded bilateral contusion injuries at cervical level 5 (C5) using a commercially available impactor (the IH device). Three separate experiments were carried

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e4f66e5984bc03c10571cf0501d66c0
https://doi.org/10.1016/j.expneurol.2009.09.028

Preparative alkaline urea gradient PAGE: Application to purification of extraordinarily-stable disulfide-linked homodimer of human growth hormone

Autor: Roberto M. Aguilar, Luis S. Haro, Alexei L. Grigorian, Jesus Muñoz, Andrew O. Martinez, Juan J. Bustamante

Publikováno v: ELECTROPHORESIS. 28:3829-3836

The 40-60 pituitary human growth hormone (hGH) isoforms are so similar in their physico-chemical properties (charge, size, hydrophobicity) that the limited resolutions of chromatographic separation methodologies have not permitted most of them to be

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d30ef5c112b5db87b9ccb276269e420
https://doi.org/10.1002/elps.200700201

Biochemistry and pharmacology of rabbit cardiac growth hormone (GH) receptors

Autor: Rafael Flores, C.C López-Guajardo, Roberto M. Aguilar, Juan J. Bustamante, Luis S. Haro, Andrew O. Martinez, P. Hernandez

Publikováno v: Molecular and Cellular Endocrinology. 152:179-187

In this report we present the first in-depth description of the biochemical and pharmacological properties of rabbit cardiac GH receptors. The apparent M r ’s of the [ 125 I]human (h) GH-receptor complexes were 380, 205, 90, 62, 52 and 38 kDa as de

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31ad87f5ad25c6333936d7882c6731af
https://doi.org/10.1016/s0303-7207(99)00047-7

Growth hormone responsive neural precursor cells reside within the adult mammalian brain

Autor: Rodney L. Rietze, Daniel G. Blackmore, Beatrice Large, Michael J. Waters, Roberto M. Aguilar, Brent A. Reynolds, Luis S. Haro, Mohammad Ghasem Golmohammadi

Publikováno v: Blackmore, Daniel G; Reynolds, Brent A; Golmohammadi, Mohammad G; Large, Beatrice; Aguilar, Roberto M; Haro, Luis; et al.(2012). Growth hormone responsive neural precursor cells reside within the adult mammalian brain. Scientific Reports, 2, 250. doi: 10.1038/srep00250. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/88t430pq
Scientific Reports

The detection of growth hormone (GH) and its receptor in germinal regions of the mammalian brain prompted our investigation of GH and its role in the regulation of endogenous neural precursor cell activity. Here we report that the addition of exogeno

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6fa06fc546c26b2b4a58cff67bbfcd6
https://doi.org/10.1038/srep00250

Separation of proteins with a molecular mass difference of 2 kDa utilizing preparative double-inverted gradient polyacrylamide gel electrophoresis under nonreducing conditions: Application to the isolation of 24 kDa human growth hormone.

Autor: Juan J. Bustamante, Macario Garcia, Leticia Gonzalez, Jesus Garcia, Rafael Flores, Roberto M. Aguilar, Ana Trevino, Luis Benavides, Andrew O. Martinez, Luis S. Haro

Publikováno v: Electrophoresis; Dec2005, Vol. 26 Issue 23, p4389-4395, 0p