Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Roberto J. Brea"'
Autor:
Shuaijiang Jin, Roberto J. Brea, Andrew K. Rudd, Stuart P. Moon, Matthew R. Pratt, Neal K. Devaraj
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Sequestration of reactants in lipid vesicles is a strategy prevalent in biological systems to raise the rate and specificity of chemical reactions. Here, the authors show that micelle-assisted reactions facilitate native chemical ligation between a p
Externí odkaz:
https://doaj.org/article/d523faaf6776431fa7a2b80e8cddfeb5
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-8 (2019)
The origin of phospholipids, the primary constituents of cell membranes, is uncertain. Here, the authors develop an in vitro system to synthesize phospholipid molecules from water-soluble single-chain amphiphilic precursors via a reaction catalysed b
Externí odkaz:
https://doaj.org/article/89bca9b9c80c40c190a8c51af0b8b13d
Autor:
Shuaijiang Jin, Roberto J. Brea, Andrew K. Rudd, Stuart P. Moon, Matthew R. Pratt, Neal K. Devaraj
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-2 (2021)
A Correction to this paper has been published: https://doi.org/10.1038/s41467-021-22508-2
Externí odkaz:
https://doaj.org/article/ec3e440211dd48658ef588780b581bba
Autor:
Roberto J. Brea, Neal K. Devaraj
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-7 (2017)
Molecules that act as both autocatalysts and material precursors offer exciting prospects for self-synthesizing materials. Here, the authors design a triazole peptide that self-replicates and then self-assembles into nanostructures, coupling autocata
Externí odkaz:
https://doaj.org/article/9e2ada1f838c4430a6e9efa70a5f0f0f
Autor:
Roberto J. Brea, Neal K. Devaraj
Publikováno v:
ACS Central Science, Vol 3, Iss 6, Pp 524-525 (2017)
Externí odkaz:
https://doaj.org/article/73875e3e66974a9bb8fbc254354f3f3a
Publikováno v:
Journal of the American Chemical Society. 143:11235-11242
Despite the central importance of lipid membranes in cellular organization, it is challenging to reconstitute their de novo formation from minimal chemical and biological elements. Here we describe a chemoenzymatic route to membrane-forming non-canon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::907c031317980a0f0164ef2f5aaadf0d
https://doi.org/10.1021/jacs.1c05394
https://doi.org/10.1021/jacs.1c05394
Publikováno v:
Current opinion in chemical biology. 71
This review comes from a themed issue on Synthetic Biomolecules (2022); Edited by Neal K. Devaraj and Shinya Tsukiji Financiado para publicación en acceso aberto: Universidade da Coruña/CISUG [Abstract] Lipids constitute one of the most enigmatic f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e84e2b4675b9f341816115938fb1e53f
https://pubmed.ncbi.nlm.nih.gov/36116189
https://pubmed.ncbi.nlm.nih.gov/36116189
Autor:
Henrike Niederholtmeyer, Kira A. Podolsky, Ahanjit Bhattacharya, Jing-Jin Song, Chu-Hsien Tsai, Neal K. Devaraj, Sunil K. Sinha, Roberto J. Brea, Rupak Bhattacharya
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 117, iss 31
Proc Natl Acad Sci U S A
Proc Natl Acad Sci U S A
Living cells segregate molecules and reactions in various subcellular compartments known as organelles. Spatial organization is likely essential for expanding the biochemical functions of synthetic reaction systems, including artificial cells. Many s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb909bf7a0b04b7ef013b750aa94c613
https://doi.org/10.1073/pnas.2004408117
https://doi.org/10.1073/pnas.2004408117
Temperature-Dependent Reversible Morphological Transformations in N-Oleoyl β-d -Galactopyranosylamine
Publikováno v:
J Phys Chem B
Amphiphilic molecules self-assemble into supramolecular structures of various sizes and morphologies depending on their molecular packing and external factors. Transformations between various self-assembled morphologies are a matter of great fundamen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::decbe32b801a6c89048bf86cd9c6895c
https://doi.org/10.1021/acs.jpcb.0c01410
https://doi.org/10.1021/acs.jpcb.0c01410
Autor:
Judith Flores, Roberto J. Brea, Alejandro Lamas, Alessandro Fracassi, Marta Salvador‐Castell, Cong Xu, Carlos R. Baiz, Sunil K. Sinha, Neal K. Devaraj
Publikováno v:
Angewandte Chemie (International ed. in English). 61(29)
Cell membranes define the boundaries of life and primarily consist of phospholipids. Living organisms assemble phospholipids by enzymatically coupling two hydrophobic tails to a soluble polar head group. Previous studies have taken advantage of micel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4958655f582c64fef3768b65fa122149
https://pubmed.ncbi.nlm.nih.gov/35546783
https://pubmed.ncbi.nlm.nih.gov/35546783