Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Roberto Guerciolini"'
Autor:
Sarah I. Sheikh, Roberto Guerciolini
Publikováno v:
New England Journal of Medicine. 381:1181-1182
Autor:
Roberto Guerciolini, Michael J. Wargovich, Cindy J. Woods, Steven Blotner, Jonathan Hauptman, Dennis J. Ahnen
Publikováno v:
Clinical Gastroenterology and Hepatology. 5:1291-1299
Orlistat is a weight management agent that selectively inhibits gastrointestinal lipase activity. Because of orlistat's mode of action, increased fecal fat is presented to the colonic mucosa, and fecal bile acid and free fatty acid composition may be
Autor:
Roberto Guerciolini, Andrew J Dorner, Gualberto Ruaño, Shiew-Mei Huang, Jerry M. Collins, Sue-Jane Wang
Publikováno v:
Pharmacogenomics. 5:513-517
Gualberto Ruano1,2, Jerry M Collins3, Andrew J Dorner4, Sue-Jane Wang5, Roberto Guerciolini6 & Shiew-Mei Huang†7 †Author for correspondence 1President, Genomas LLC, New Haven, CT, USA 2Department of Biochemistry and Molecular Biology, George Wash
Autor:
Peter J. Elliott, Owen A. O'Connor, Stephanie Stahl, Steven L. Soignet, Robert Z. Orlowski, Julian Adams, Natalie D. Depcik-Smith, Roberto Guerciolini, Steven C. Novick, Mary Jo Lehman, Jessica K. Anderson, Christine S. Pien, Thomas E. Stinchcombe, Beverly S. Mitchell, Albert S. Baldwin, Dixie Lee Esseltine, Thomas C. Shea, Rita Bhagat
Publikováno v:
Journal of Clinical Oncology. 20:4420-4427
PURPOSE: To determine the maximum-tolerated dose (MTD), dose-limiting toxicity (DLT), and pharmacodynamics (PD) of the proteasome inhibitor bortezomib (previously known as PS-341) in patients with refractory hematologic malignancies. PATIENTS AND MET
Publikováno v:
Obesity Research. 9:364-367
Objective: To compare the effects of chitosan and orlistat on fecal fat excretion. Research Methods and Procedure: A randomized, open-label, two-period sequential design study was used. A total of 12 healthy adult volunteers within 20% of their ideal
Autor:
Angela T. Melia, James A. Sadowski, Roberto Guerciolini, Jianguo Zhi, Sharon Passe, Susan G. Koss-Twardy, Ashok Rakhit
Publikováno v:
The Journal of Clinical Pharmacology. 36:659-666
To assess the effect of orlistat on the pharmacokinetics and pharmacodynamics of warfarin, a third-party blind, placebo-controlled, randomized, two-way crossover study was performed in 12 healthy volunteers. Each participant received single 30-mg ora
Autor:
James O. Kahn, Francesca T. Aweeka, Katrin Peter, May Mak, Melton B. Affrime, Amira Al-Uzri, Carmen Dett, David L. Cutler, Roberto Guerciolini, John G. Gambertoglio, Jose Franco
Publikováno v:
The Journal of Clinical Pharmacology. 35:856-864
Combination therapy with zidovudine and recombinant human granulocyte-macrophage colony stimulating factor (rHu GM-CSF) may be warranted, owing to the bone marrow suppressive effects of zidovudine. A study of 16 patients, 8 of whom had acquired immun
Autor:
Peter K. Kaiser, Gail Reisen, Edward Quinlan, Brian Short, Homayoun Tabandeh, Roberto Guerciolini, R.C. Andrew Symons, Jennifer A. Lockridge, Syed Mahmood Shah, Quan Dong Nguyen, Diana V. Do
Publikováno v:
American journal of ophthalmology. 150(1)
Purpose To assess the safety, tolerability, pharmacokinetics, and dose-limiting toxicity of single intravitreal injection of Sirna-027, a small interfering RNA targeting vascular endothelial growth factor receptor-1, in patients with choroidal neovas
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 49(1)
Liquid chromatography coupled to mass spectrometry (LC/MS) was used to elucidate early biomarkers of bortezomib response in multiple myeloma patients. The change in serum myeloma M-protein level, maintained for a minimum of 6 weeks, is used as one of
Publikováno v:
Clinica Chimica Acta. 186:359-374
Nicotinamide N-methyltransferase (NNMT) catalyzes the N-methylation of nicotinamide, pyridine, and structurally related compounds. The products of this reaction are positively charged pyridinium ions that cannot be removed from aqueous solution by si