Zobrazeno 1 - 10
of 204
pro vyhledávání: '"Roberto F Machado"'
Autor:
Julio D Duarte, Ankit A Desai, Justin R Sysol, Taimur Abbasi, Amit R Patel, Roberto M Lang, Akash Gupta, Joe G N Garcia, Victor R Gordeuk, Roberto F Machado
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0163013 (2016)
Diastolic dysfunction is common in sickle cell disease (SCD), and is associated with an increased risk of mortality. However, the molecular pathogenesis underlying this development is poorly understood. The aim of this study was to identify a gene ex
Externí odkaz:
https://doaj.org/article/4d8849aebbee4a859569a94654b875a0
Autor:
Julia H Indik, Vineet Nair, Ruslan Rafikov, Iwan S Nyotowidjojo, Jaskanwal Bisla, Mayank Kansal, Devang S Parikh, Melissa Robinson, Anand Desai, Megha Oberoi, Akash Gupta, Taimur Abbasi, Zain Khalpey, Amit R Patel, Roberto M Lang, Samuel C Dudley, Bum-Rak Choi, Joe G N Garcia, Roberto F Machado, Ankit A Desai
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164526 (2016)
Sudden death is a leading cause of mortality in sickle cell disease, implicating ventricular tachyarrhythmias. Prolonged QTc on an electrocardiogram (ECG), commonly seen with myocardial ischemia, is a known risk for polymorphic ventricular tachycardi
Externí odkaz:
https://doaj.org/article/9f2a02da94f940d194963dbc14c1f793
Publikováno v:
Vascular Health and Risk Management, Vol Volume 2, Pp 411-422 (2006)
Christopher F Barnett1,2, Roberto F Machado1,21Critical Care Medicine Department, Clinical Center, National Institutes of Health, Bethesda, MD, USA; 2Vascular Medicine Branch, National Heart Lung and Blood Institute, National Institutes of Health, Be
Externí odkaz:
https://doaj.org/article/814404f3313547e0a64470e1d45ba495
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e91879 (2014)
Environmental nontuberculous mycobacteria (NTM) are ubiquitous organisms with which humans commonly interact. The epidemiologic characteristics of NTM diseases including mortality rate and its associated factors remain largely unknown. In this study,
Externí odkaz:
https://doaj.org/article/74aaa09634bb4f81a618a67fd764e8ef
Autor:
Adriana M Zimnicka, Haiyang Tang, Qiang Guo, Frank K Kuhr, Myung-Jin Oh, Jun Wan, Jiwang Chen, Kimberly A Smith, Dustin R Fraidenburg, Moumita S R Choudhury, Irena Levitan, Roberto F Machado, Jack H Kaplan, Jason X-J Yuan
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e90544 (2014)
Pulmonary vascular remodeling and increased arterial wall stiffness are two major causes for the elevated pulmonary vascular resistance and pulmonary arterial pressure in patients and animals with pulmonary hypertension. Cellular copper (Cu) plays an
Externí odkaz:
https://doaj.org/article/13005cca34f249ebac95ee232fff417b
Autor:
Mark T Gladwin, Robyn J Barst, J Simon R Gibbs, Mariana Hildesheim, Vandana Sachdev, Mehdi Nouraie, Kathryn L Hassell, Jane A Little, Dean E Schraufnagel, Lakshmanan Krishnamurti, Enrico Novelli, Reda E Girgis, Claudia R Morris, Erika Berman Rosenzweig, David B Badesch, Sophie Lanzkron, Oswaldo L Castro, James G Taylor, Jonathan C Goldsmith, Gregory J Kato, Victor R Gordeuk, Roberto F Machado, walk-PHaSST Investigators and Patients
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e99489 (2014)
The role of pulmonary hypertension as a cause of mortality in sickle cell disease (SCD) is controversial.We evaluated the relationship between an elevated estimated pulmonary artery systolic pressure and mortality in patients with SCD. We followed pa
Externí odkaz:
https://doaj.org/article/36ede0ae221943d1887a84c560bea8cc
Autor:
Jiwang Chen, Gang Feng, Qiang Guo, Juliane B Wardenburg, Simon Lin, Ichiro Inoshima, Ryan Deaton, Jason X J Yuan, Joe G N Garcia, Roberto F Machado, Michael Otto, Richard G Wunderink
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e70176 (2013)
Community associated methicillin-resistant Staphylococcus aureus (CA-MRSA) is an emerging threat to human health throughout the world. Rodent MRSA pneumonia models mainly focus on the early innate immune responses to MRSA lung infection. However, the
Externí odkaz:
https://doaj.org/article/55b5247d5be348b9ba1e5e28b657b9ef
Autor:
Tong Zhou, Wei Zhang, Nadera J Sweiss, Edward S Chen, David R Moller, Kenneth S Knox, Shwu-Fan Ma, Michael S Wade, Imre Noth, Roberto F Machado, Joe G N Garcia
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e44818 (2012)
Sarcoidosis, a systemic granulomatous syndrome invariably affecting the lung, typically spontaneously remits but in ~20% of cases progresses with severe lung dysfunction or cardiac and neurologic involvement (complicated sarcoidosis). Unfortunately,
Externí odkaz:
https://doaj.org/article/2657016fb3344bc88ece2409bdeca797
Autor:
Xu Zhang, Jihyun Song, Binal N. Shah, Jin Han, Taif Hassan, Galina Miasniakova, Adelina Sergueeva, Sergei Nekhai, Roberto F. Machado, Mark T. Gladwin, Santosh L. Saraf, Josef T. Prchal, Victor R. Gordeuk
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Transcriptional changes in compensatory erythropoiesis in sickle cell anemia (SCA) and their disease modulation are unclear. We detected 1226 differentially expressed genes in hemoglobin SS reticulocytes compared to non-anemic hemoglobin AA
Externí odkaz:
https://doaj.org/article/28e138e102b34c009297029c6f5d995c
Autor:
Xu Zhang, Jihyun Song, Binal N. Shah, Jin Han, Taif Hassan, Galina Miasniakova, Adelina Sergueeva, Sergei Nekhai, Roberto F. Machado, Mark T. Gladwin, Santosh L. Saraf, Josef T. Prchal, Victor R. Gordeuk
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-2 (2023)
Externí odkaz:
https://doaj.org/article/573a5bc3df20468ea570fbd6777c5c58