Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Roberto Dinami"'
Autor:
Sara Iachettini, Irene Terrenato, Manuela Porru, Serena Di Vito, Angela Rizzo, Carmen D’Angelo, Eleonora Petti, Roberto Dinami, Carmen Maresca, Anna Di Benedetto, Aldo Palange, Antonino Mulè, Angela Santoro, Antonella Palazzo, Paola Fuso, Antonella Stoppacciaro, Patrizia Vici, Lorena Filomeno, Francesca Sofia Di Lisa, Teresa Arcuri, Eriseld Krasniqi, Alessandra Fabi, Annamaria Biroccio, Pasquale Zizza
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-16 (2024)
Abstract Background Breast Cancer (BC) can be classified, due to its heterogeneity, into multiple subtypes that differ for prognosis and clinical management. Notably, triple negative breast cancer (TNBC) – the most aggressive BC form – is refract
Externí odkaz:
https://doaj.org/article/b5288dd001e444b193813380b0f2304e
Autor:
Giovanni Blandino, Roberto Dinami, Marco Marcia, Eleni Anastasiadou, Brid M. Ryan, Alina Catalina Palcau, Luigi Fattore, Giulia Regazzo, Rosanna Sestito, Rossella Loria, Ana Belén Díaz Méndez, Maria Chiara Cappelletto, Claudio Pulito, Laura Monteonofrio, George A. Calin, Gabriella Sozzi, Jit Kong Cheong, Ranit Aharonov, Gennaro Ciliberto
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-16 (2023)
Abstract The 5th Workshop IRE on Translational Oncology was held in Rome (Italy) on 27–28 March at the IRCCS Regina Elena National Cancer Institute. This meeting entitled “The New World of RNA diagnostics and therapeutics” highlightes the signi
Externí odkaz:
https://doaj.org/article/3a1f4e3c811547579a213904c93a8094
Autor:
Roberto Dinami, Luca Pompili, Eleonora Petti, Manuela Porru, Carmen D'Angelo, Serena Di Vito, Angela Rizzo, Virginia Campani, Giuseppe De Rosa, Alejandra Bruna, Violeta Serra, Miguel Mano, Mauro Giacca, Carlo Leonetti, Gennaro Ciliberto, Madalena Tarsounas, Antonella Stoppacciaro, Stefan Schoeftner, Annamaria Biroccio
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 1, Pp n/a-n/a (2023)
Abstract The telomeric repeat‐binding factor 2 (TRF2) is a telomere‐capping protein that plays a key role in the maintenance of telomere structure and function. It is highly expressed in different cancer types, and it contributes to cancer progre
Externí odkaz:
https://doaj.org/article/329d8d14529b400796d6b5c09e60a4e4
Autor:
Roberto Dinami, Manuela Porru, Carla Azzurra Amoreo, Isabella Sperduti, Marcella Mottolese, Simonetta Buglioni, Daniele Marinelli, Marcello Maugeri-Saccà, Andrea Sacconi, Giovanni Blandino, Carlo Leonetti, Giuliana Di Rocco, Alessandra Verdina, Francesca Spinella, Francesco Fiorentino, Gennaro Ciliberto, Annamaria Biroccio, Pasquale Zizza
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 39, Iss 1, Pp 1-13 (2020)
Abstract Background Colorectal cancer is one of most common tumors in developed countries and, despite improvements in treatment and diagnosis, mortality rate of patients remains high, evidencing the urgent need of novel biomarkers to properly identi
Externí odkaz:
https://doaj.org/article/767fa99324964b889013aba888fd2d7a
Autor:
Eleonora Petti, Valentina Buemi, Antonina Zappone, Odessa Schillaci, Pamela Veneziano Broccia, Roberto Dinami, Silvia Matteoni, Roberta Benetti, Stefan Schoeftner
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
LncRNA TERRA forms RNA-DNA hybrids at telomere sites leading to telomere instability. Here the authors identify the RNA interacting factors NONO and SFPQ as proteins that interact with TERRA and telomere chromatin and reveal putative roles for these
Externí odkaz:
https://doaj.org/article/f8f8d328c17a48d78dd6073e811e9d80
Autor:
Paola Ostano, Erica Salvati, Chiara Cingolani, Isabella Sperduti, Eleonora Petti, Roberto Dinami, Annamaria Biroccio, Giovanna Chiorino, Marcella Mottolese, Carmen D'Angelo, Giovanni Blandino, Eric Gilson, Manuela Porru, Carla Azzurra Amoreo, Angela Maria Rizzo, Pasquale Zizza, Rosita Russo, Angela Chambery, Carlo Leonetti, Julien Cherfils-Vicini, Andrea Sacconi
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, 2019
Nucleic Acids Research, Oxford University Press, 2019
HAL
Nucleic Acids Research, 2019
Nucleic Acids Research, Oxford University Press, 2019
HAL
The telomeric protein TRF2 is overexpressed in several human malignancies and contributes to tumorigenesis even though the molecular mechanism is not completely understood. By using a high-throughput approach based on the multiplexed Luminex X-MAP te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c726ef57436c4d1002916566186f3f5d
http://europepmc.org/articles/PMC6468246
http://europepmc.org/articles/PMC6468246
Autor:
Roberto Dinami, Eleonora Petti, Manuela Porru, Angela Rizzo, Federica Ganci, Andrea Sacconi, Paola Ostano, Giovanna Chiorino, Livio Trusolino, Giovanni Blandino, Gennaro Ciliberto, Pasquale Zizza, Annamaria Biroccio
Publikováno v:
Cancer Letters. 533:215607
The Telomeric Repeat binding Factor 2 (TRF2), a key protein involved in telomere integrity, is over-expressed in several human cancers and promotes tumor formation and progression. Recently, TRF2 has been also found outside telomeres where it can aff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03ef24097531ea4681a13f115d7a9595
https://doi.org/10.1016/j.canlet.2022.215607
https://doi.org/10.1016/j.canlet.2022.215607
Autor:
Odessa Schillaci, Stefan Schoeftner, Silvia Matteoni, Valentina Buemi, Roberto Dinami, Eleonora Petti, Roberta Benetti, Pamela Veneziano Broccia, Antonina Zappone
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Nature Communications
Nature Communications
In vertebrates, the telomere repeat containing long, non-coding RNA TERRA is prone to form RNA:DNA hybrids at telomeres. This results in the formation of R-loop structures, replication stress and telomere instability, but also contributes to alternat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce1139f6767617aea0e6d8a6924098a4
https://doi.org/10.1038/s41467-019-08863-1
https://doi.org/10.1038/s41467-019-08863-1
Autor:
Eleonora Petti, Valentina Buemi, Fabian Jordi, Maria A. Blasco, Roberta Benetti, Stefan Schoeftner, Roberto Dinami
Publikováno v:
Cell Cycle. 14:1438-1446
The Suv39h1 and Suv39h2 H3K9 histone methyltransferases (HMTs) have a conserved role in the formation of constitutive heterochromatin and gene silencing. Using a transgenic mouse model system we demonstrate that elevated expression of Suv39h1 increas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7eaa4be768207dce7ff549996033517
https://doi.org/10.1080/15384101.2015.1021517
https://doi.org/10.1080/15384101.2015.1021517
Autor:
Stefan Schoeftner, Giovanni Blandino, Mauro Giacca, Silvano Piazza, Antonina Zappone, Yari Ciani, Andrea Sacconi, Roberto Dinami, Eleonora Petti, Valentina Buemi, Roberta Benetti, Rosanna Sestito, Miguel Mano
Publikováno v:
Oncotarget
// Roberto Dinami 1, 2, * , Valentina Buemi 1, 3, * , Rosanna Sestito 2, *, ** , Antonina Zappone 1, 3 , Yari Ciani 4 , Miguel Mano 5 , Eleonora Petti 1, 2, 3 , Andrea Sacconi 6 , Giovanni Blandino 6 , Mauro Giacca 5 , Silvano Piazza 4 , Roberta Bene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bea0cee3a876a012bbb4428847e2b6e
https://pubmed.ncbi.nlm.nih.gov/29221158
https://pubmed.ncbi.nlm.nih.gov/29221158