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Autor:
Margarete M. Trachez, Gisele Zapata-Sudo, Roberto T. Sudo, Guilherme C Montes, Ken-ichiro Hayashida, Masahito Kawatani, Carlos Es Monteiro, Roberto D Moreira, Aluízio N Santos
Publikováno v:
Journal of Pain Research. 11:2453-2462
Objective To demonstrate the antinociceptive and antihypersensitivity mechanisms of Cris-104 (1-{2-[5-(4-fluorophenyl)-1H-pyrazol-4-yl]ethyl}piperidine), a novel selective α4β2* nicotinic acetylcholine receptor (nAChR) agonist, in rodent acute/infl