Learning from –omics strategies applied to uncover Haemophilus influenzae host-pathogen interactions: Current status and perspectives

Autor: Nahikari López-López, Celia Gil-Campillo, Roberto Díez-Martínez, Junkal Garmendia

Publikováno v: Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 3042-3050 (2021)

Haemophilus influenzae has contributed to key bacterial genome sequencing hallmarks, as being not only the first bacterium to be genome-sequenced, but also starring the first genome-wide analysis of chromosomes directly transformed with DNA from a di

Externí odkaz: https://doaj.org/article/4af5b16eb53448458be6e33aa70e3930

Essential Topics for the Regulatory Consideration of Phages as Clinically Valuable Therapeutic Agents: A Perspective from Spain

Autor: Roberto Vázquez, Roberto Díez-Martínez, Pilar Domingo-Calap, Pedro García, Diana Gutiérrez, Maite Muniesa, María Ruiz-Ruigómez, Rafael Sanjuán, María Tomás, María Ángeles Tormo-Mas, Pilar García

Publikováno v: Microorganisms, Vol 10, Iss 4, p 717 (2022)

Antibiotic resistance is one of the major challenges that humankind shall face in the short term. (Bacterio)phage therapy is a valuable therapeutic alternative to antibiotics and, although the concept is almost as old as the discovery of phages, its

Externí odkaz: https://doaj.org/article/f7a84f1a4988449b94d6a456f22c9ca8

Table S5, S6 and S7 from Zebrafish: Speeding Up the Cancer Drug Discovery Process

Autor: Julen Oyarzabal, Roberto Díez-Martínez, Iranzu Lamberto, Irene de Miguel, Patricia Letrado

This file contains supplemental tables of zebrafish cancer models carried out in zebrafish using genetics approaches, allograft, xenograft and orthotopic assays

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::590cd82ef50dc5e0e533b30b21f88c29
https://doi.org/10.1158/0008-5472.22419951.v1

Systematic Roadmap for Cancer Drug Screening Using Zebrafish Embryo Xenograft Cancer Models: Melanoma Cell Line as a Case Study

Autor: Roberto Díez-Martínez, Irene Palacios, María C. Montoya, Patricia Letrado, Holly Mole, Jorge Barriuso, Julen Oyarzabal, Adam Hurlstone

Publikováno v: Cancers
Volume 13
Issue 15
Letrado, P, Mole, H, Montoya, M, Palacios, I, Barriuso, J, Hurlstone, A, Díez-martínez, R & Oyarzabal, J 2021, ' Systematic Roadmap for Cancer Drug Screening Using Zebrafish Embryo Xenograft Cancer Models: Melanoma Cell Line as a Case Study ', Cancers, vol. 13, no. 15, pp. 3705 . https://doi.org/10.3390/cancers13153705
Cancers, Vol 13, Iss 3705, p 3705 (2021)

Zebrafish embryo tumor transplant models are widely utilized in cancer research. Compared with traditional murine models, the small size and transparency of zebrafish embryos combined with large clutch sizes that increase statistical power and cheap

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2608ab6abb25d441ace591c974b517ea
https://pubmed.ncbi.nlm.nih.gov/34359605

Glucose catabolism by respiration assisted fermentation leading to acetate production has a key contribution to chronic patient airway infection by Haemophilus influenzae

Autor: Roberto Díez-Martínez, Goizeder Almagro, José Ramos-Vivas, Juncal Garmendia Garcia, Javier Pozueta-Romero, Sara Martí, Begoña Euba, Nahikari López-López, Ulrike Kappler, Mariette Barbier

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
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Resumen del trabajo presentado en el European Respiratory Society International Congress, celebrado en Madrid (España), del 28 de septiembre al 2 de octubre de 2019
Many chronic pulmonary diseases have aspects of their pathogenesis influenced b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63c79881ec8c9b912f2ba27f6a5e6f95
http://hdl.handle.net/10261/207860