Výsledky vyhledávání - "Roberto Cotellese"

Akademický článek

Differential Regulation of Wingless-Wnt/c-Jun N-Terminal Kinase Crosstalk via Oxidative Eustress in Primary and Metastatic Colorectal Cancer Cells

Autor: Gitana Maria Aceto, Sara Pagotto, Francesco Domenico Del Pizzo, Concetta Saoca, Federico Selvaggi, Rosa Visone, Roberto Cotellese, M’hammed Aguennouz, Rossano Lattanzio, Teresa Catalano

Publikováno v: Biomedicines, Vol 12, Iss 8, p 1816 (2024)

In the tumor microenvironment (TME), ROS production affects survival, progression, and therapy resistance in colorectal cancer (CRC). H2O2-mediated oxidative stress can modulate Wnt/β-catenin signaling and metabolic reprogramming of the TME. Current

Externí odkaz: https://doaj.org/article/4243d0169bf34fb0939aa9a6ba6ca21b

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Akademický článek

Infectious Agents Induce Wnt/β-Catenin Pathway Deregulation in Primary Liver Cancers

Autor: Teresa Catalano, Federico Selvaggi, Diana Liberata Esposito, Roberto Cotellese, Gitana Maria Aceto

Publikováno v: Microorganisms, Vol 11, Iss 7, p 1632 (2023)

Interaction between infectious agents and liver tissue, as well as repeated and extreme biological events beyond adaptive capacities, may result in pathological conditions predisposing people to development of primary liver cancers (PLCs). In adults,

Externí odkaz: https://doaj.org/article/0bd960ffd53a48a9b9d23cfdd2c95274

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Akademický článek

Effects of H2O2 Treatment Combined With PI3K Inhibitor and MEK Inhibitor in AGS Cells: Oxidative Stress Outcomes in a Model of Gastric Cancer

Autor: Luca Savino, Maria Carmela Di Marcantonio, Carmelo Moscatello, Roberto Cotellese, Lucia Centurione, Raffaella Muraro, Gitana Maria Aceto, Gabriella Mincione

Publikováno v: Frontiers in Oncology, Vol 12 (2022)

Gastric cancer is worldwide the fifth and third cancer for incidence and mortality, respectively. Stomach wall is daily exposed to oxidative stress and BER system has a key role in the defense from oxidation-induced DNA damage, whilst ErbB receptors

Externí odkaz: https://doaj.org/article/254c6f520a714b36b754e4f5b26fa8cc

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Akademický článek

Emerging Role of Oxidative Stress on EGFR and OGG1-BER Cross-Regulation: Implications in Thyroid Physiopathology

Autor: Carmelo Moscatello, Maria Carmela Di Marcantonio, Luca Savino, Emira D’Amico, Giordano Spacco, Pasquale Simeone, Paola Lanuti, Raffaella Muraro, Gabriella Mincione, Roberto Cotellese, Gitana Maria Aceto

Publikováno v: Cells, Vol 11, Iss 5, p 822 (2022)

Thyroid diseases have a complex and multifactorial aetiology. Despite the numerous studies on the signals referable to the malignant transition, the molecular mechanisms concerning the role of oxidative stress remain elusive. Based on its strong oxid

Externí odkaz: https://doaj.org/article/96e21e925a8544f09338867bab5fedc3

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Akademický článek

Minimally Invasive Treatment of Sporadic Burkitt’s Lymphoma Causing Ileocaecal Invagination

Autor: Paolo Panaccio, Michele Fiordaliso, Domenica Testa, Lorenzo Mazzola, Mariangela Battilana, Roberto Cotellese, Federico Selvaggi

Publikováno v: Case Reports in Surgery, Vol 2018 (2018)

Introduction. Primary NHL (non-Hodgkin lymphoma) of the colon represents only 0.2% to 1.2% of all colonic malignancies. Burkitt’s lymphoma (BL) is usually a disease reported in children and young people, most of them associated with EBV or HIV infe

Externí odkaz: https://doaj.org/article/7ea7cb77afa9448aa078f7760cd7464c

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