Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Roberto Carrio"'
Autor:
Roberto Carrio, Margot Cucchetti, Mikielia Devonish, Louis Poisson, Mihaela Babiceanu, Andrew Kettring, Yingchun Liu, Donald Jackson, Evan Gomes, Jeremy Baudhuin, Donald R. Drake, Valeria Fantin, Anthony Byers, Ingrid Sassoon
Publikováno v:
Cancer Research. 83:6378-6378
T cell exhaustion is a state of dysfunction that frequently occurs during chronic infections and cancer due to persistent antigen stimulation and inflammation. It is defined by poor effector function, sustained expression of inhibitory receptors, and
Publikováno v:
International Journal of Molecular Medicine. 37:133-138
Cell-mediated immunity is an important defense mechanism against pathogens and developing tumor cells. The thymus is the main lymphoid organ involved in the formation of the cell-mediated immune response by the maturation and differentiation of lymph
Autor:
Roberto Carrio, Thais Agostini, Margot P. Cleary, Eduardo Lamas-Basulto, Marta Torroella-Kouri, Olivia Casas, Ana M. Santander, Lidia G. Sanchez, Omar Lopez-Ocejo, Ruben R. Gonzalez-Perez
Publikováno v:
Cancers, Vol 7, Iss 1, Pp 143-178 (2015)
Cancers
Volume 7
Issue 1
Pages 143-178
Cancers
Volume 7
Issue 1
Pages 143-178
The relationship between obesity and breast cancer (BC) has focused on serum factors. However, the mammary gland contains adipose tissue (AT) which may enable the crosstalk between adipocytes and tumor cells contributing to tumor macrophage recruitme
Publikováno v:
Immunologic Research. 57:70-80
Mucin 1 (MUC1) is a polymorphic type 1 transmembrane protein found on the apical surface of normal cells lining the lumen of ducts and glands. Mucins are thought to provide mucosal protection from environmental exposures and carcinogens. An altered f
Autor:
Ramon Garcia-Areas, Marta Torroella-Kouri, Stephania Libreros, Yoshimi Shibata, Vijaya Iragavarapu-Charyulu, Roberto Carrio
Publikováno v:
International Journal of Cancer. 131:377-386
Disseminated metastasis accounts for over 90% of breast cancer deaths. Recently, elevated serum levels of a glycoprotein known as chitinase-3 like-protein-1 (CHI3L1) has been correlated with poor prognosis and shorter survival of patients with metast
Publikováno v:
The Journal of Immunology. 172:7315-7323
Although much is known concerning the immunobiology of CD8+ T memory cells, the initial events favoring the generation of CD8+ T memory cells remain poorly defined. Using a culture system that yields memory-like CD8+ T cells, we show that 1 day after
Autor:
Roberto Carrio, Roderic Guigó, Josep F. Abril, Bru Cormand, Moisès Burset, Noureddine Loukili, Jesús Merino, Víctor M. Díaz, Marta Valeri, Alfons Macaya, Florenci Serras, Juan José Lozano, Montserrat Corominas, Timothy M. Thomson
Publikováno v:
Recercat. Dipósit de la Recerca de Catalunya
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UEV proteins are enzymatically inactive variants of the E2 ubiquitin-conjugating enzymes that regulate noncanonical elongation of ubiquitin chains. In Saccharomyces cerevisiae, UEV is part of the RAD6-mediated error-free DNA repair pathway. In mammal
Autor:
Roberto Carrio, Jesús Merino, Serge Clément, Stéphane Schurmans, Jens Behrends, Valérie Pouillon
Publikováno v:
Genomics. 62:260-271
SHIP2 is a new member of the inositol polyphosphate 5-phosphatase family showing homology to SHIP1. The structure of both enzymes is characterized by the presence of a 5' SH2 domain, a central catalytic domain, and a 3' proline-rich region. Recent re
Autor:
Maria Muñiz, Gabriel Núñez, Tania S. Gourley, Irene Garcia, Shu Chen, Naohiro Inohara, Takeyoshi Koseki, Yuanming Hu, Roberto Carrio, Jesús Merino
Publikováno v:
Journal of Biological Chemistry. 273:32479-32486
We have identified and characterized Diva, which is a novel regulator of apoptosis. Sequence analysis revealed that Diva is a member of the Bcl-2 family of proteins containing Bcl-2 homology domain 1, 2, 3, and 4 (BH1, BH2, BH3, and BH4) regions and
Autor:
Diana M. Lopez, Roberto Carrio
Publikováno v:
Immunologic research. 57(1-3)
The thymus is a central lymphoid organ critical for the development and maintenance of an effective peripheral T-cell repertoire. Most important, it provides a specialized environment for the selection of rearranged clones that will function appropri