Cytokines dysregulation in schizophrenia: A systematic review of psychoneuroimmune relationship

Autor: Roberto Carlos Agis-Balboa, Tania Rivera-Baltanás, África González-Fernández, José M. Olivares, Carlos Spuch, Daniela Rodrigues-Amorim, Hector J. Caruncho

Publikováno v: Schizophrenia Research. 197:19-33

Introduction: Schizophrenia is a multifactorial psychiatric disease with complex interactions among the brain and the immune system. A psycho-immune relationship underling schizophrenia is supported by several studies and integrates a specific area o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53114e0a14265346b93f98ab64b31219
https://doi.org/10.1016/j.schres.2017.11.023

Chronic exposure to cannabinoids during adolescence causes long-lasting behavioral deficits in adult mice

Autor: S. Hoyer-Fender, Eva Benito, Jordi Tomas-Roig, Ursula Havemann-Reinecke, Fabiana Piscitelli, Roberto Carlos Agis-Balboa, V. Di Marzo

Publikováno v: Addiction Biology. 22:1778-1789

Regular use of marijuana during adolescence enhances the risk of long-lasting neurobiological changes in adulthood. The present study was aimed at assessing the effect of long-term administration of the synthetic cannabinoid WIN55212.2 during adolesc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::77894d1251ebca1ae331cfa8598bb40b
https://doi.org/10.1111/adb.12446

Formin 2 links neuropsychiatric phenotypes at young age to an increased risk for dementia

Autor: Andrea Schmitt, Nelson Rebola, Susanne Burkhardt, Christophe Mulle, Eva Benito, Ivana Delalle, Roberto Carlos Agis-Balboa, Alexander Jatzko, Gaurav Jain, Patricia A. Zunszain, Sanaz Bahari-Javan, Paulo S. Pinheiro, Julius C. Pape, Markus Dettenhofer, Peter Falkai, Michael Gertig, Farahnaz Sananbenesi, Cemil Kerimoglu, Elisabeth B. Binder, Andre Fischer

Publikováno v: Agís-Balboa, R C, Pinhero, P, Rebola, N, Kerimoglu, C, Benito, E, Gertig, M, Bahari-Javan, S, Jain, G, Burkhardt, S, Delalle, I, Jatzko, A, Dettenhofer, M, Zunszain, P A, Schmitt, A, Falkai, P, Pape, J C, Binder, E B, Mulle, C, Fischer, A & Sananbenesi, F 2017, ' Formin 2 links neuropsychiatric phenotypes at young age to an increased risk for dementia ', The EMBO journal, vol. 36, no. 19, pp. 2815-2828 . https://doi.org/10.15252/embj.201796821
The EMBO journal 36(19), 2815-2828 (2017). doi:10.15252/embj.201796821
RUNA. Repositorio da Consellería de Sanidade e Sergas
Servizo Galego de Saúde (SERGAS)
EMBO JOURNAL
The EMBO Journal

Age-associated memory decline is due to variable combinations of genetic and environmental risk factors. How these risk factors interact to drive disease onset is currently unknown. Here we begin to elucidate the mechanisms by which post-traumatic st

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88c13c908d6e0f860de3484a7771db35
https://kclpure.kcl.ac.uk/ws/files/80023520/Formin_2_links_neuropsychiatric_AGILS_BALBOA_Publishedonline2August2017_GOLD_VoR_CC_BY_.pdf

KMT2A and KMT2B Mediate Memory Function by Affecting Distinct Genomic Regions

Autor: Cemil Kerimoglu, Roman M. Stilling, Gaurav Jain, Roberto Carlos Agis-Balboa, Andrea Kranz, Lalit Kaurani, Eva Benito, Susanne Burkhardt, A. Francis Stewart, Hendrik Urbanke, M. Sadman Sakib, Rashi Halder, Andre Fischer, Vincenzo Capece

Publikováno v: Cell Reports
Cell Reports, Vol 20, Iss 3, Pp 538-548 (2017)
Cell Reports. Amsterdam, Netherlands: Elsevier (2017).
RUNA. Repositorio da Consellería de Sanidade e Sergas
Servizo Galego de Saúde (SERGAS)
Cell reports 20(3), 538-548 (2017). doi:10.1016/j.celrep.2017.06.072

Kmt2a and Kmt2b are H3K4 methyltransferases of the Set1/Trithorax class. We have recently shown the importance of Kmt2b for learning and memory. Here, we report that Kmt2a is also important in memory formation. We compare the decrease in H3K4 methyla

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8537136464ce2f720f9306de8ebee10d

Insulin growth factor binding protein 7 is a novel target to treat dementia

Autor: Ivana Delalle, Roberto Carlos Agis-Balboa, Hope Y Agbemenyah, Susanne Burkhardt, Andre Fischer

Publikováno v: Neurobiology of disease 62, 135-143 (2014). doi:10.1016/j.nbd.2013.09.011
Neurobiology of Disease, Vol 62, Iss, Pp 135-143 (2014)

Alzheimer's disease (AD) is the most common form of dementia in the elderly but effective therapeutic strategies to treat AD are not yet available. This is also due to the fact that the pathological mechanisms that drive the pathogenesis of sporadic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a426254e62e02e39de9d9f5455d843b1
https://doi.org/10.1016/j.nbd.2013.09.011