Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Roberto Beteta-Göbel"'
Autor:
Javier Fernández-Díaz, Roberto Beteta-Göbel, Manuel Torres, Joan Cabot, Paula Fernández-García, Victoria Lladó, Pablo V. Escribá, Xavier Busquets
Publikováno v:
Frontiers in Physiology, Vol 12 (2022)
Cell proliferation in pancreatic cancer is determined by a complex network of signaling pathways. Despite the extensive understanding of these protein-mediated signaling processes, there are no significant drug discoveries that could considerably imp
Externí odkaz:
https://doaj.org/article/9b26cfcb5c6344c197ec8f97977d75b3
Autor:
Roberto Beteta-Göbel, Marc Miralles, Javier Fernández-Díaz, Raquel Rodríguez-Lorca, Manuel Torres, Paula Fernández-García, Pablo V. Escribá, Victoria Lladó
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 17, p 9902 (2022)
Pancreatic cancer has a high mortality rate due to its aggressive nature and high metastatic rate. When coupled to the difficulties in detecting this type of tumor early and the lack of effective treatments, this cancer is currently one of the most i
Externí odkaz:
https://doaj.org/article/6cd240aee00e49fcaf9a7b4715d5f7df
Autor:
Manuel Torres, Sebastià Parets, Javier Fernández-Díaz, Roberto Beteta-Göbel, Raquel Rodríguez-Lorca, Ramón Román, Victoria Lladó, Catalina A. Rosselló, Paula Fernández-García, Pablo V. Escribá
Publikováno v:
Membranes, Vol 11, Iss 12, p 919 (2021)
Membranes are mainly composed of a lipid bilayer and proteins, constituting a checkpoint for the entry and passage of signals and other molecules. Their composition can be modulated by diet, pathophysiological processes, and nutritional/pharmaceutica
Externí odkaz:
https://doaj.org/article/a6501e75763b4dac802885cc825c6f36
Abstract 4869: Furin and Notch signaling pathway as part of the 2OHOA landscape against glioblastoma
Autor:
Raquel Rodríguez-Lorca, Roberto Beteta-Göbel, Ramón Román, Manuel Torres, Victoria Llado, Pablo V. Escribá, Paula Fernández-García
Publikováno v:
Cancer Research. 83:4869-4869
Glioblastoma (GBM) is the most common and aggressive cancer tumor of the central nervous system, with only 12-15 months of patients’ median survival. Melitherapy is a novel therapeutic platform based on the regulation of the membrane’s structure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1bee333b9fe4815cb002129f1f58d9ef
https://doi.org/10.1158/1538-7445.am2023-4869
https://doi.org/10.1158/1538-7445.am2023-4869
Autor:
Ramón Román, Javier Fernández-Díaz, Victoria Lladó, Raquel Rodríguez-Lorca, Catalina Ana Rosselló, Pablo V. Escribá, Paula Fernández-García, Sebastià Parets, Manuel Torres, Roberto Beteta-Göbel
Publikováno v:
Membranes
Membranes, Vol 11, Iss 919, p 919 (2021)
Membranes, Vol 11, Iss 919, p 919 (2021)
Membranes are mainly composed of a lipid bilayer and proteins, constituting a checkpoint for the entry and passage of signals and other molecules. Their composition can be modulated by diet, pathophysiological processes, and nutritional/pharmaceutica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8854d250bc3b8c8b8aa24f8f4738fbf
https://pubmed.ncbi.nlm.nih.gov/34940418
https://pubmed.ncbi.nlm.nih.gov/34940418
Autor:
Paula Fernández-García, Catalina Ana Rosselló, Raquel Rodríguez-Lorca, Roberto Beteta-Göbel, Javier Fernández-Díaz, Xavier Busquets, Victoria Lladó, Pablo V. Escribá
Publikováno v:
Cancers
Volume 11
Issue 1
Cancers, Vol 11, Iss 1, p 88 (2019)
Volume 11
Issue 1
Cancers, Vol 11, Iss 1, p 88 (2019)
Background: 2-Hydroxyoleic acid (2OHOA) is particularly active against glioblastoma multiforme (GBM) and successfully finished a phase I/IIA trial in patients with glioma and other advanced solid tumors. However, its mechanism of action is not fully
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::155850023c8a449c460a0a0896482c5f
Autor:
Maitane Ibarguren, Raquel Rodríguez-Lorca, Roberto Beteta-Göbel, Francisca Guardiola-Serrano, Silvia Terés, Xavier Busquets, María Alonso-Sande, David J. López, Manuel Torres, Mónica Higuera, Pablo V. Escribá
Publikováno v:
Oncotarget
The plasma membrane is an attractive target for new anticancer drugs, not least because regulating its lipid structure can control multiple signaling pathways involved in cancer cell proliferation, differentiation and survival. Accordingly, the novel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6db5bab1fb374de6cd24648d5f5b0b82
Autor:
Francisca Guardiola-Serrano, David J. López, Silvia Terés, Rafael Álvarez, Roberto Beteta-Göbel, Maitane Ibarguren, Raquel Rodríguez-Lorca, Pablo V. Escribá, María Alonso-Sande, Xavier Busquets
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 354(2)
Membrane lipid therapy is a novel approach to rationally design or discover therapeutic molecules that target membrane lipids. This strategy has been used to design synthetic fatty acid analogs that are currently under study in clinical trials for th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b1cf1723206f447cdf95a9e7462c1fa
https://pubmed.ncbi.nlm.nih.gov/26065701
https://pubmed.ncbi.nlm.nih.gov/26065701