Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Roberto Bernardoni"'
Autor:
Hoai Nam Nguyen, Grazia Galleri, Antonio Rassu, Cristina Ciampelli, Roberto Bernardoni, Manuela Galioto, Diego Albani, Claudia Crosio, Ciro Iaccarino
Publikováno v:
Biomedicines, Vol 12, Iss 7, p 1555 (2024)
Pathological mutations in the LRRK2 gene are the major genetic cause of Parkinson’s disease (PD). Although several animal models with either LRRK2 down- or over-expression have been developed, the physiological function of LRRK2 remains elusive. LR
Externí odkaz:
https://doaj.org/article/18723701c2364257908f98cd2fcdbe2e
Autor:
Daria Messelodi, Silvia Strocchi, Salvatore Nicola Bertuccio, Pascale Baden, Valentina Indio, Federico M. Giorgi, Alberto Taddia, Salvatore Serravalle, Sabrina Valente, Alessio di Fonzo, Emanuele Frattini, Roberto Bernardoni, Annalisa Pession, Daniela Grifoni, Michela Deleidi, Annalisa Astolfi, Andrea Pession
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-13 (2023)
Abstract Gaucher Disease (GD), the most common lysosomal disorder, arises from mutations in the GBA1 gene and is characterized by a wide spectrum of phenotypes, ranging from mild hematological and visceral involvement to severe neurological disease.
Externí odkaz:
https://doaj.org/article/9bd17c548d7444108e9aef7cad700e02
Autor:
Cristina Ciampelli, Grazia Galleri, Silvia Puggioni, Milena Fais, Lucia Iannotta, Manuela Galioto, Marta Becciu, Elisa Greggio, Roberto Bernardoni, Claudia Crosio, Ciro Iaccarino
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 16, p 12656 (2023)
Pathological mutations in leucine-rich repeat kinase 2 (LRRK2) gene are the major genetic cause of Parkinson’s disease (PD). Multiple lines of evidence link LRRK2 to the control of vesicle dynamics through phosphorylation of a subset of RAB protein
Externí odkaz:
https://doaj.org/article/10fd71bc49e54702a107ea4f32cd346d
Autor:
Roberto Bernardoni, Giorgia Giordani, Elisabetta Signorino, Sara Monticelli, Francesca Messa, Monica Pradotto, Valentina Rosso, Enrico Bracco, Angela Giangrande, Giovanni Perini, Giuseppe Saglio, Daniela Cilloni
Publikováno v:
Haematologica, Vol 104, Iss 4 (2019)
The oncoprotein BCR-ABL1 triggers chronic myeloid leukemia. It is clear that the disease relies on constitutive BCR-ABL1 kinase activity, but not all the interactors and regulators of the oncoprotein are known. We describe and validate a Drosophila l
Externí odkaz:
https://doaj.org/article/18a7196037cc47e8a9dfa1e138287748
Autor:
Anna Popkova, Roberto Bernardoni, Celine Diebold, Véronique Van de Bor, Bernd Schuettengruber, Inma González, Ana Busturia, Giacomo Cavalli, Angela Giangrande
Publikováno v:
PLoS Genetics, Vol 8, Iss 12, p e1003159 (2012)
The Gcm/Glide transcription factor is transiently expressed and required in the Drosophila nervous system. Threshold Gcm/Glide levels control the glial versus neuronal fate choice, and its perdurance triggers excessive gliogenesis, showing that its t
Externí odkaz:
https://doaj.org/article/30af4f9758bf481fb18147ce81b078f1
Autor:
Stefania Trazzi, Giovanni Perini, Roberto Bernardoni, Monica Zoli, Joseph C Reese, Andrea Musacchio, Giuliano Della Valle
Publikováno v:
PLoS ONE, Vol 4, Iss 6, p e5832 (2009)
CENP-C is a fundamental component of functional centromeres. The elucidation of its structure-function relationship with centromeric DNA and other kinetochore proteins is critical to the understanding of centromere assembly. CENP-C carries two region
Externí odkaz:
https://doaj.org/article/57ac3be007154c9da0cbaad9bd3136e9
Autor:
Giovanni Perini, Giovanni Martinelli, Michele Baccarani, Murray D. Norris, Michelle Haber, Chiara Perrod, Roberto Bernardoni, Thea Kalebic, Emanuele Valli, Sandra Durante, Carolina Terragna, Samuele Gherardi, Daniel Diolaiti, Simona Soverini, Nunzio Iraci, Antonio Porro
PDF file - 2651K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90578cf0f21d7c9504d519a32c5715cf
https://doi.org/10.1158/1541-7786.22519342.v1
https://doi.org/10.1158/1541-7786.22519342.v1
Autor:
Monica Pradotto, F Messa, Giovanni Perini, Sara Monticelli, Enrico Bracco, Angela Giangrande, Daniela Cilloni, Elisabetta Signorino, Valentina Rosso, Roberto Bernardoni, Giuseppe Saglio, Giorgia Giordani
Publikováno v:
Haematologica
Haematologica, Ferrata Storti Foundation, 2019, 104 (4), pp.717-728. ⟨10.3324/haematol.2018.198267⟩
Haematologica, Ferrata Storti Foundation, 2019, 104 (4), pp.717-728. ⟨10.3324/haematol.2018.198267⟩
The oncoprotein BCR-ABL1 triggers chronic myeloid leukemia. It is clear that the disease relies on constitutive BCR-ABL1 kinase activity, but not all the interactors and regulators of the oncoprotein are known. We describe and validate a Drosophila l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddc61704a2e0acea3a2a8cb9f411e79f
https://hal.archives-ouvertes.fr/hal-03501286
https://hal.archives-ouvertes.fr/hal-03501286
Autor:
Marilena Barraco, Giorgia Simonetti, Angela Giangrande, Giorgia Giordani, Viviana Guadagnuolo, Roberto Bernardoni, Giovanni Perini, Giovanni Martinelli
Publikováno v:
Oncotarget
Oncotarget, Impact journals, 2016, 7 (34), pp.55313-55327. ⟨10.18632/oncotarget.10879⟩
Oncotarget, 2016, 7 (34), pp.55313-55327. ⟨10.18632/oncotarget.10879⟩
Oncotarget, Impact journals, 2016, 7 (34), pp.55313-55327. ⟨10.18632/oncotarget.10879⟩
Oncotarget, 2016, 7 (34), pp.55313-55327. ⟨10.18632/oncotarget.10879⟩
// Giorgia Giordani 1, 5, * , Marilena Barraco 1, 6, * , Angela Giangrande 2 , Giovanni Martinelli 3 , Viviana Guadagnuolo 3 , Giorgia Simonetti 3 , Giovanni Perini 1, 4 , Roberto Bernardoni 1, 4 1 Department of Pharmacy and Biotechnology (FaBiT), Un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c7d6bfdf9a1fc89763fb1c1b25afc4d
https://doi.org/10.18632/oncotarget.10879
https://doi.org/10.18632/oncotarget.10879
Autor:
Murray D. Norris, Paolo Pigini, Roberto Bernardoni, F. Ferrucci, Michelle Haber, Giorgio Milazzo, Sara Monticelli, S. Di Giacomo, Daniela Erriquez, Roberto Ciaccio, Stefania Purgato, Giovanni Perini
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms. 1863:194645
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91b57b8f4109e2258b2761dfe025e63a
https://doi.org/10.1016/j.bbagrm.2020.194645
https://doi.org/10.1016/j.bbagrm.2020.194645