Zobrazeno 1 - 10
of 143
pro vyhledávání: '"Roberto Benelli"'
Autor:
Emanuele Gotelli, Stefano Soldano, Carol Feghali-Bostwick, Paola Montagna, Rosanna Campitiello, Paola Contini, Marco Mora, Roberto Benelli, Elvis Hysa, Sabrina Paolino, Carmen Pizzorni, Alberto Sulli, Vanessa Smith, Maurizio Cutolo
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionSystemic sclerosis (SSc) is a complex autoimmune connective tissue disease characterized by microvascular damage, immune system reactivity and progressive fibrosis of skin and internal organs. Interstitial lung disease is the leading caus
Externí odkaz:
https://doaj.org/article/73b2a5ac44a74f418cb974b1d666da14
Autor:
Amr Khalifa, Ana Guijarro, Silvia Ravera, Nadia Bertola, Maria Pia Adorni, Bianca Papotti, Lizzia Raffaghello, Roberto Benelli, Pamela Becherini, Asmaa Namatalla, Daniela Verzola, Daniele Reverberi, Fiammetta Monacelli, Michele Cea, Livia Pisciotta, Franco Bernini, Irene Caffa, Alessio Nencioni
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Identifying oncological applications for drugs that are already approved for other medical indications is considered a possible solution for the increasing costs of cancer treatment. Under the hypothesis that nutritional stress through fasti
Externí odkaz:
https://doaj.org/article/09f7f094d29d492b991f7ee272e9b6d8
Autor:
Feliciana Morelli, Serena Matis, Roberto Benelli, Laura Salvini, Maria Raffaella Zocchi, Alessandro Poggi
Publikováno v:
Cells, Vol 13, Iss 10, p 862 (2024)
Relevant advances have been made in the management of relapsed/refractory (r/r) Hodgkin Lymphomas (HL) with the use of the anti-CD30 antibody–drug conjugate (ADC) brentuximab–vedotin (Bre–Ved). Unfortunately, most patients eventually progress d
Externí odkaz:
https://doaj.org/article/4eeb12c0bf66416fa5c75d95090f98e1
Autor:
Amr Khalifa, Ana Guijarro, Silvia Ravera, Nadia Bertola, Maria Pia Adorni, Bianca Papotti, Lizzia Raffaghello, Roberto Benelli, Pamela Becherini, Asmaa Namatalla, Daniela Verzola, Daniele Reverberi, Fiammetta Monacelli, Michele Cea, Livia Pisciotta, Franco Bernini, Irene Caffa, Alessio Nencioni
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/cd8c959e696f4fb4bdb263dcc766062e
Autor:
Roberto Benelli, Alessandro Poggi, Delfina Costa, Laura Salvini, Samuele Tardito, Francesca Tosetti, Federico Villa, Maria Raffaella Zocchi
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 12 (2022)
Background Antibody-drug conjugates (ADC) are essential therapeutic options to treat solid and hematological cancers. The anti-epidermal growth factor-receptor (EGFR) antibody cetuximab (Cet) is used for the therapy of colorectal carcinoma (CRC). Ant
Externí odkaz:
https://doaj.org/article/9478de75c6dd41bfac3163ce2e094adb
Autor:
Delfina Costa, Roberta Venè, Simona Coco, Luca Longo, Francesca Tosetti, Stefano Scabini, Luca Mastracci, Federica Grillo, Alessandro Poggi, Roberto Benelli
Publikováno v:
Cells, Vol 12, Iss 4, p 664 (2023)
The p38 inhibitor SB202190 is a necessary component of the medium used for normal colorectal mucosa cultures. Sato et al. suggested that the primary activity of SB202190 may be EGFR signaling stabilization, causing an increased phosphorylation of Erk
Externí odkaz:
https://doaj.org/article/249b59f0bf524e23ae11bca2225a796d
Autor:
Alessandro Poggi, Roberto Benelli, Roberta Venè, Delfina Costa, Nicoletta Ferrari, Francesca Tosetti, Maria Raffaella Zocchi
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
It is well established that natural killer (NK) cells are involved in both innate and adaptive immunity. Indeed, they can recognize molecules induced at the cell surface by stress signals and virus infections. The functions of NK cells in the gut are
Externí odkaz:
https://doaj.org/article/33987bd6e1f74054bcb406d0e99a4096
Autor:
Simonetta Carluccio, Daniela Martinelli, Maria Elisabetta Federica Palamà, Rui Cruz Pereira, Roberto Benelli, Ana Guijarro, Ranieri Cancedda, Chiara Gentili
Publikováno v:
Cells, Vol 9, Iss 4, p 1052 (2020)
Regenerative strategies for human articular cartilage are still challenging despite the presence of resident progenitor cell population. Today, many efforts in the field of regenerative medicine focus on the use of platelet derivatives due to their a
Externí odkaz:
https://doaj.org/article/97042a5f31ff427a9b6b2d07c84231db
Autor:
Roberta Venè, Delfina Costa, Raffaella Augugliaro, Sebastiano Carlone, Stefano Scabini, Gianmaria Casoni Pattacini, Maurizio Boggio, Simonetta Zupo, Federica Grillo, Luca Mastracci, Francesca Pitto, Simona Minghelli, Nicoletta Ferrari, Francesca Tosetti, Emanuele Romairone, Maria C. Mingari, Alessandro Poggi, Roberto Benelli
Publikováno v:
Cells, Vol 9, Iss 3, p 683 (2020)
Observational/retrospective studies indicate that prostaglandin-endoperoxide synthase-2 (PTGS2) inhibitors could positively affect colorectal cancer (CRC) patients’ survival after diagnosis. To obtain an acceptable cost/benefit balance, the inclusi
Externí odkaz:
https://doaj.org/article/6a1fd0cd32f9456e97cb88deab54454e
Autor:
Delfina Costa, Roberta Venè, Roberto Benelli, Emanuele Romairone, Stefano Scabini, Silvia Catellani, Barbara Rebesco, Luca Mastracci, Federica Grillo, Simona Minghelli, Fabrizio Loiacono, Maria Raffaella Zocchi, Alessandro Poggi
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Mesenchymal stromal cells (MSC) present in the tumor microenvironment [usually named tumor-associated fibroblasts (TAF)] can exert immunosuppressive effects on T and natural killer (NK) lymphocytes, favoring tumor immune escape. We have analyzed this
Externí odkaz:
https://doaj.org/article/0937d82b023f4f10bce6c3564db7d24e