Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Roberto Aiolfi"'
Autor:
Mario Catarinella, Andrea Monestiroli, Giulia Escobar, Amleto Fiocchi, Ngoc Lan Tran, Roberto Aiolfi, Paolo Marra, Antonio Esposito, Federica Cipriani, Luca Aldrighetti, Matteo Iannacone, Luigi Naldini, Luca G Guidotti, Giovanni Sitia
Publikováno v:
EMBO Molecular Medicine, Vol 8, Iss 2, Pp 155-170 (2016)
Abstract Colorectal cancer (CRC) metastatic dissemination to the liver is one of the most life‐threatening malignancies in humans and represents the leading cause of CRC‐related mortality. Herein, we adopted a gene transfer strategy into mouse he
Externí odkaz:
https://doaj.org/article/72326cef96b64b368da85c5f40530022
Autor:
Giovanni Sitia, Matteo Iannacone, Roberto Aiolfi, Masanori Isogawa, Nico van Rooijen, Cristina Scozzesi, Marco E Bianchi, Ulrich H von Andrian, Francis V Chisari, Luca G Guidotti
Publikováno v:
PLoS Pathogens, Vol 7, Iss 6, p e1002061 (2011)
Kupffer cells (KCs) are widely considered important contributors to liver injury during viral hepatitis due to their pro-inflammatory activity. Herein we utilized hepatitis B virus (HBV)-replication competent transgenic mice and wild-type mice infect
Externí odkaz:
https://doaj.org/article/044318fc73ee4dedbd344ec92754bd20
Autor:
Roberto Aiolfi, Hiroshi Deguchi, Jose F. Fernández, Jeanine Ahmed, Miriam Hauer-Jensen, Juan Carlos de la Torre, Laurent O. Mosnier
Publikováno v:
Blood. 140:1674-1675
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eefdb456da9a14746e2f8a8fe8bac071
https://doi.org/10.1182/blood-2022-163863
https://doi.org/10.1182/blood-2022-163863
Autor:
Roberto Aiolfi, Giovanni Sitia, Matteo Iannacone, Ivan Brunetta, Luca G. Guidotti, Zaverio M. Ruggeri
Publikováno v:
Science Signaling. 15
Bleeding correlates with disease severity in viral hemorrhagic fevers. We found that the increase in type I interferon (IFN-I) in mice caused by infection with the Armstrong strain of lymphocytic choriomeningitis virus (LCMV; an arenavirus) reduced t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecee73dcc2bcd354d554fe41d743184f
https://doi.org/10.1126/scisignal.abb0384
https://doi.org/10.1126/scisignal.abb0384
Publikováno v:
Blood
Coronavirus disease 2019 (COVID-19) is caused by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Most infected individuals are asymptomatic or show only mild symptoms, but 20% of infected individuals become severely ill r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9aab8aa441454750b0e51c9c27b3224a
http://europepmc.org/articles/PMC8701651
http://europepmc.org/articles/PMC8701651
Autor:
Megan J. Welch, Zaverio M. Ruggeri, Lucy E Horton, Roberto Aiolfi, Brian M. Sullivan, Brian C. Ware, Alessandro Zarpellon, Michael B. A. Oldstone
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 115(33)
Understanding of T cell exhaustion and successful therapy to restore T cell function was first described using Clone (Cl) 13 variant selected from the lymphocytic choriomeningitis virus (LCMV) Armstrong (ARM) 53b parental strain. T cell exhaustion pl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d8d1f78a09f607e3138dbe2b5327248
https://pubmed.ncbi.nlm.nih.gov/30061383
https://pubmed.ncbi.nlm.nih.gov/30061383
Autor:
Roberto Aiolfi, Giovanni Sitia
Publikováno v:
Cellular & Molecular Immunology. 12:264-268
Platelets play a known role in the maintenance of vascular homeostasis, but these cells are emerging as important cellular mediators of acute and chronic inflammatory diseases. Platelets are key elements in the pathogenesis of acute and chronic liver
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2424ebc450bf14a2f640e8f12a7a4b75
https://doi.org/10.1038/cmi.2014.124
https://doi.org/10.1038/cmi.2014.124
Publikováno v:
Blood. 134:1074-1074
Viral hemorrhagic fever (VHF) refers to a group of diverse acute human diseases caused by single stranded RNA viruses typically associated with fever, vascular damage and abnormal vascular barrier function. These infections are a continuing threat to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34e2c608cddfbe05a50f6a26a495fb85
https://doi.org/10.1182/blood-2019-128940
https://doi.org/10.1182/blood-2019-128940
Autor:
Giovanni Sitia, Roberto Aiolfi
Publikováno v:
Journal of Hepatocellular Carcinoma
Platelets, the chief effectors of vascular homeostasis, have been identified as important players in the pathogenesis of both acute and chronic liver disease in preclinical models of hepatitis B viral infection. Platelets are thought to promote the a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcd3f106673741091e5cf06ad9fb3862
https://pubmed.ncbi.nlm.nih.gov/27508186
https://pubmed.ncbi.nlm.nih.gov/27508186
Autor:
Annarita Miluzio, Daniela Brina, Stefano Biffo, M. Bonomo, Luca G. Guidotti, Francesco Falciani, Roberto Aiolfi, Kim Clarke, Sara Ricciardi
Publikováno v:
Journal of thrombosis and haemostasis : JTH. 13(11)
BACKGROUND Ribosomopathies constitute a class of inherited disorders characterized by defects in ribosome biogenesis and function. Classically, bone marrow (BM) failure is a clinical symptom shared between these syndromes, including Shwachman-Bodian-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eaa60cf1d05939a6af91f8e6fdfb7bba
https://pubmed.ncbi.nlm.nih.gov/26391622
https://pubmed.ncbi.nlm.nih.gov/26391622