Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Roberto, Puzone"'
Autor:
Francesca Piaggio, Michela Croce, Francesco Reggiani, Paola Monti, Cinzia Bernardi, Marianna Ambrosio, Barbara Banelli, Mehmet Dogrusöz, Ralf Jockers, Domenico Bordo, Roberto Puzone, Silvia Viaggi, Domenico Coviello, Francesco B. Lanza, Martina Bartolucci, Andrea Petretto, Carlo Mosci, Rosaria Gangemi, Pieter A. van der Velden, Martine J. Jager, Ulrich Pfeffer, Adriana Amaro
Publikováno v:
European Journal of Cancer, 170, 27-41. ELSEVIER SCI LTD
Background and aim of the study: Mutations in the G alpha-genes GNAQ and GNA11 are found in 85-90% of uveal melanomas (UM). Aim of the study is to understand whether the mutations in both genes differentially affect tumor characteristics and outcome
Autor:
D. A. Coviello, Ulrich Pfeffer, Alessandra Eva, Cinzia Bernardi, Francesca Piaggio, Roberto Puzone, Adriana Amaro, Michela Croce, Michael Zeschnigk, Silvia Viaggi, Annalisa Barla, Davide Cangelosi, Pieter A. van der Velden, Veronica Tozzo, Martine J. Jager, Serena Patrone
Publikováno v:
Cancers, 11(11)
Cancers
Cancers, Vol 11, Iss 11, p 1688 (2019)
Volume 11
Issue 11
Cancers
Cancers, Vol 11, Iss 11, p 1688 (2019)
Volume 11
Issue 11
Background: Uveal melanoma (UM), a rare cancer of the eye, is characterized by initiating mutations in the genes G-protein subunit alpha Q (GNAQ), G-protein subunit alpha 11 (GNA11), cysteinyl leukotriene receptor 2 (CYSLTR2), and phospholipase C bet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a59ad0403ffaca9e1adbe3cebeea768
http://hdl.handle.net/1887/121228
http://hdl.handle.net/1887/121228
Autor:
Piaggio, Francesca, Tozzo, Veronica, Bernardi, Cinzia, Michela, Croce, LO SICCO, Claudia, Gangemi, Rosaria, Roberto, Puzone, Viaggi, Silvia, Patrone, Serena, Barla, Annalisa, Coviello, Domenico, Jager, Martine J., van der Velden, Pieter A., Davide, Cangelosi, Alessandra, Eva, Ferrini, Silvano, Pfeffer, Ulrich, Amaro, ADRIANA AGNESE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3710::1b29d154b3f22b0a74c0e99d658449e9
https://hdl.handle.net/11567/1001558
https://hdl.handle.net/11567/1001558
Autor:
Francesca Nasciuti, Alessandro Poggi, Sandra Salvi, Carlo Mosci, Patrizia Perri, Adriana Amaro, Roberto Puzone, Valentina Mirisola, Mauro Truini, Ulrich Pfeffer, Alessia Isabella Esposito, Francesco Lanza, Francesca Tosetti, Alessandra Musso, Giovanna Angelini
Publikováno v:
European Journal of Cancer. 49:3353-3365
Despite advances in surgery and radiotherapy of uveal melanoma (UM), many patients develop distant metastases that poorly respond to therapy. Improved therapies for the metastatic disease are therefore urgently needed. Expression of the epidermal gro
Autor:
Ulrich Pfeffer, Roberto Puzone
Publikováno v:
European journal of human genetics : EJHG. 25(3)
Genome-wide association studies have revealed many breast cancer (BC) risk-associated genetic variants that might functionally interact with other molecular determinants of BC. We analysed the association of 21 known risk-associated single-nucleotide
Autor:
Paola Queirolo, Ulrich Pfeffer, Francesco Lanza, Paola Visconti, Roberto Puzone, Federica Parodi, Carlo Mosci, Anna Morabito, Maria Pia Pistillo, Luca Anselmi, Marina Gualco, Michael Zeschnigk, Federica Raggi, Mario Mandalà, Konrad Diedrich, Maria Carla Bosco, Irena Maric, Laura Spano, Domenico A. Coviello, Adriana Amaro, Silvia Viaggi, Giovanna Angelini, Luigi Varesio, Paola Ghiorzo, Cornelia Götz
Importance Chromosome 6p amplification is associated with more benign behavior for uveal melanomas (UMs) with an otherwise high risk of metastasis conferred by chromosome 3 monosomy. Chromosome 6p contains several members of the B7 family of immune r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c08ed17299ddb12c2b6ab1b807d6a07
http://hdl.handle.net/11391/1480974
http://hdl.handle.net/11391/1480974
Autor:
Roberto Puzone, Franco Celada, Myriam F. Wlodarczyk, Liisa K. Selin, Anke R. M. Kraft, Laurie L. Kenney, Siwei Nie
Publikováno v:
Autoimmunity
Heterologous immunity is a common phenomenon present in all infections. Most of the time it is beneficial, mediating protective immunity, but in some individuals that have the wrong crossreactive response it leads to a cascade of events that result i
Autor:
David A. Thorley-Lawson, Shalyn Catherine Clute, Franco Celada, Nuray Aslan, John L. Sullivan, Levi B. Watkin, Katherine Luzuriaga, Roberto Puzone, Raymond M. Welsh, Yuri N. Naumov, Liisa K. Selin
Publikováno v:
The Journal of Immunology. 185:6753-6764
Memory T cells cross-reactive with epitopes encoded by related or even unrelated viruses may alter the immune response and pathogenesis of infection by a process known as heterologous immunity. Because a challenge virus epitope may react with only a
Autor:
Pier Giacomo Betta, Roberta Libener, Matteo Puntoni, Barbara Bobbio, Franco Montefiore, Luca Ruggiero, Roberto Puzone, Laura Paleari, Massimo Maffezzini, Paola Marroni
Publikováno v:
The International Journal of Biological Markers. 25:200-206
Background Prostate cancer is the second most frequent cause of tumor-related deaths in men in Western countries. The selection and evaluation of new markers might help to overcome the limits of the most widely used diagnostic tool, the prostate-spec
Publikováno v:
Vaccine. 27:833-845
In an agent-based computer model, we simulate the formation and recall of anti-virus immunological memory. Specifically we try to predict what will happen, both to the response and to memory, when the second infecting virus is partly different from t