Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Roberto, Iorio"'
Autor:
Lorenza Fagnani, Pierangelo Bellio, Antonio Di Giulio, Lisaurora Nazzicone, Roberto Iorio, Sabrina Petricca, Nicola Franceschini, Laura Bertarini, Donatella Tondi, Giuseppe Celenza
Publikováno v:
Heliyon, Vol 10, Iss 19, Pp e38445- (2024)
In response to the COVID-19 pandemic, identifying effective treatments against SARS-CoV-2 has become of utmost importance. This study elucidates the mechanism by which perlatolinic acid, a lichen-derived secondary metabolite, non-competitively inhibi
Externí odkaz:
https://doaj.org/article/537d0238561f4bc484357a747ef8cf9c
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-17 (2024)
Abstract Intercellular mitochondrial transfer (MT) is a newly discovered form of cell-to-cell signalling involving the active incorporation of healthy mitochondria into stressed/injured recipient cells, contributing to the restoration of bioenergetic
Externí odkaz:
https://doaj.org/article/f1943cfebabe4db58aac6d09a7cb12c0
Autor:
Sabrina Petricca, Veronica Carnicelli, Carla Luzi, Benedetta Cinque, Giuseppe Celenza, Roberto Iorio
Publikováno v:
Antioxidants, Vol 12, Iss 6, p 1142 (2023)
Triazole and imidazole fungicides are an emerging class of contaminants with an increasing and ubiquitous presence in the environment. In mammals, their reproductive toxicity has been reported. Concerning male reproduction, a combinatorial activity o
Externí odkaz:
https://doaj.org/article/62bcf9a67e494eb793a71adf87b68fbf
Publikováno v:
European Journal of Cell Biology, Vol 101, Iss 3, Pp 151225- (2022)
Metabolic alterations have been observed in many cancer types. The deregulated metabolism has thus become an emerging hallmark of the disease, where the metabolism is frequently rewired to aerobic glycolysis. This has led to the concept of “metabol
Externí odkaz:
https://doaj.org/article/5bbde54b4ecb4e6a8bc4af0d594f1282
Autor:
Alessandro Colapietro, Peiying Yang, Alessandra Rossetti, Andrea Mancini, Flora Vitale, Sharmistha Chakraborty, Stefano Martellucci, Francesco Marampon, Vincenzo Mattei, Giovanni Luca Gravina, Roberto Iorio, Robert A. Newman, Claudio Festuccia
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Glioblastoma multiforme (GBM) is the most common as well as one of the most malignant types of brain cancer. Despite progress in development of novel therapies for the treatment of GBM, it remains largely incurable with a poor prognosis and a very lo
Externí odkaz:
https://doaj.org/article/b13f2ebbb77347bdb1a00a5f27f9b430
Publikováno v:
Antioxidants, Vol 11, Iss 6, p 1199 (2022)
Inflammation and oxidative stress are interlinked and interdependent processes involved in many chronic diseases, including neurodegeneration, diabetes, cardiovascular diseases, and cancer. Therefore, targeting inflammatory pathways may represent a p
Externí odkaz:
https://doaj.org/article/d9f85daae2154f8dae952393277a9217
Autor:
Lorenza Fagnani, Lisaurora Nazzicone, Pierangelo Bellio, Nicola Franceschini, Donatella Tondi, Andrea Verri, Sabrina Petricca, Roberto Iorio, Gianfranco Amicosante, Mariagrazia Perilli, Giuseppe Celenza
Publikováno v:
Pharmaceuticals, Vol 15, Iss 6, p 714 (2022)
The study investigated the inhibitory activity of protocetraric and salazinic acids against SARS-CoV-2 3CLpro. The kinetic parameters were determined by microtiter plate-reading fluorimeter using a fluorogenic substrate. The cytotoxic activity was te
Externí odkaz:
https://doaj.org/article/40e52e07a0b142ebaa41557bc4b823c0
Publikováno v:
Cells, Vol 11, Iss 1, p 30 (2021)
Mitochondria are multifunctional subcellular organelles essential for cellular energy homeostasis and apoptotic cell death. It is, therefore, crucial to maintain mitochondrial fitness. Mitophagy, the selective removal of dysfunctional mitochondria by
Externí odkaz:
https://doaj.org/article/5322620c558f4ccd9acad5b93941684a
Autor:
Lorenza Fagnani, Lisaurora Nazzicone, Fabrizia Brisdelli, Luisa Giansanti, Sara Battista, Roberto Iorio, Sabrina Petricca, Gianfranco Amicosante, Mariagrazia Perilli, Giuseppe Celenza, Pierangelo Bellio
Publikováno v:
Antibiotics, Vol 10, Iss 8, p 952 (2021)
The dramatic intensification of antimicrobial resistance occurrence in pathogenic bacteria concerns the global community. The revitalisation of inactive antibiotics is, at present, the only way to go through this health system crisis and the use of a
Externí odkaz:
https://doaj.org/article/5dbaaa3893bc4ec480eb11d41cafa676
Autor:
Roberto Iorio, Maria Luigia Segnana
Publikováno v:
Eurasian Business Review. 12:475-504
Corruption research in economics has a long history. Seminal early articles, and older findings contrast with newer developments which have as yet not been measured empirically; in particular the link between corruption and innovating activities suff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a472b8cc17bac04e866324de2f79863
https://doi.org/10.1007/s40821-022-00205-4
https://doi.org/10.1007/s40821-022-00205-4