Zobrazeno 1 - 10
of 109
pro vyhledávání: '"Roberto, Contestabile"'
Autor:
Eleonora Pilesi, Giulia Tesoriere, Angelo Ferriero, Elisa Mascolo, Francesco Liguori, Luca Argirò, Chiara Angioli, Angela Tramonti, Roberto Contestabile, Cinzia Volontè, Fiammetta Vernì
Publikováno v:
Cell Death and Disease, Vol 15, Iss 6, Pp 1-13 (2024)
Abstract Vitamin B6 is a water-soluble vitamin which possesses antioxidant properties. Its catalytically active form, pyridoxal 5’-phosphate (PLP), is a crucial cofactor for DNA and amino acid metabolism. The inverse correlation between vitamin B6
Externí odkaz:
https://doaj.org/article/fa51980441b04013bdda26692f01a735
Autor:
Marco Malatesta, Emanuele Fornasier, Martino Luigi Di Salvo, Angela Tramonti, Erika Zangelmi, Alessio Peracchi, Andrea Secchi, Eugenia Polverini, Gabriele Giachin, Roberto Battistutta, Roberto Contestabile, Riccardo Percudani
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract The increasing availability of experimental and computational protein structures entices their use for function prediction. Here we develop an automated procedure to identify enzymes involved in metabolic reactions by assessing substrate con
Externí odkaz:
https://doaj.org/article/14c67f718fbf493085d50d336b285301
Autor:
Elisa Mascolo, Anna Barile, Lorenzo Stufera Mecarelli, Noemi Amoroso, Chiara Merigliano, Arianna Massimi, Isabella Saggio, Torben Hansen, Angela Tramonti, Martino Luigi Di Salvo, Fabrizio Barbetti, Roberto Contestabile, Fiammetta Vernì
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Abstract In eukaryotes, pyridoxal kinase (PDXK) acts in vitamin B6 salvage pathway to produce pyridoxal 5′-phosphate (PLP), the active form of the vitamin, which is implicated in numerous crucial metabolic reactions. In Drosophila, mutations in the
Externí odkaz:
https://doaj.org/article/98cbd0cfb2e64e8c8b4f5fe2009a0e66
Autor:
Roberto Contestabile, Martino Luigi di Salvo, Victoria Bunik, Angela Tramonti, Fiammetta Vernì
Publikováno v:
Open Biology, Vol 10, Iss 3 (2020)
A perturbed uptake of micronutrients, such as minerals and vitamins, impacts on different human diseases, including cancer and neurological disorders. Several data converge towards a crucial role played by many micronutrients in genome integrity main
Externí odkaz:
https://doaj.org/article/3902a06c081a49d09f6b0f72605c3de8
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Externí odkaz:
https://doaj.org/article/5fb2130b30f2419696fe14ec58731eb8
Autor:
Martino L. di Salvo, Mario Mastrangelo, Isabel Nogués, Manuela Tolve, Alessandro Paiardini, Carla Carducci, Davide Mei, Martino Montomoli, Angela Tramonti, Renzo Guerrini, Roberto Contestabile, Vincenzo Leuzzi
Publikováno v:
Data in Brief, Vol 15, Iss , Pp 868-875 (2017)
PNPO deficiency is responsible of severe neonatal encephalopathy, responsive to pyridoxal-5â²-phosphate (PLP) or pyridoxine. Recent studies widened the phenotype of this condition and detected new genetic variants on PNPO gene, whose pathogenetic r
Externí odkaz:
https://doaj.org/article/f013bfa8128d460e9bc017bc7e8ce9de
Autor:
Caterina Nardella, Dalila Boi, Martino L. di Salvo, Anna Barile, Jörg Stetefeld, Angela Tramonti, Roberto Contestabile
Publikováno v:
Frontiers in Molecular Biosciences, Vol 6 (2019)
Plants, algae and most bacteria synthesize 5-aminolevulinic acid (ALA), the universal precursor of tetrapyrroles such as heme, chlorophyll and coenzyme B12, by a two-step transformation involving the NADPH-dependent glutamyl-tRNA reductase (HemA), wh
Externí odkaz:
https://doaj.org/article/f6b62f13cb774065ae47e035283aa94c
Autor:
Jill Babor, Angela Tramonti, Caterina Nardella, Adam Deutschbauer, Roberto Contestabile, Valérie de Crécy-Lagard
Publikováno v:
Microbiology. 169
Pyridoxal 5′-phosphate (PLP) is the active form of vitamin B6 and a cofactor for many essential metabolic processes such as amino acid biosynthesis and one carbon metabolism. 4’-deoxypyridoxine (4dPN) is a long known B6 antimetabolite but its mec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2efb8c7cd3a53cd2917f6042558625ad
https://doi.org/10.1099/mic.0.001319
https://doi.org/10.1099/mic.0.001319
Autor:
Angela Tramonti, Roberto Contestabile, Rita Florio, Caterina Nardella, Anna Barile, Martino L. Di Salvo
Publikováno v:
Life, Vol 11, Iss 5, p 438 (2021)
Cysteine sulfinic acid decarboxylase catalyzes the last step of taurine biosynthesis in mammals, and belongs to the fold type I superfamily of pyridoxal-5′-phosphate (PLP)-dependent enzymes. Taurine (2-aminoethanesulfonic acid) is the most abundant
Externí odkaz:
https://doaj.org/article/7569477c869648469525d2f3462ded59
Autor:
Sebastiana Angelaccio, Teresa Milano, Angela Tramonti, Martino Luigi Di Salvo, Roberto Contestabile, Stefano Pascarella
Publikováno v:
Data in Brief, Vol 9, Iss C, Pp 292-313 (2016)
Detailed data from statistical analyses of the structural properties of the inter-domain linker peptides of the bacterial regulators of the family MocR are herein reported. MocR regulators are a recently discovered subfamily of bacterial regulators p
Externí odkaz:
https://doaj.org/article/f2998992d88343f8bcf5ac1e78b3cffe