Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Roberta Zangaglia"'
Autor:
Daisy Sproviero, Stella Gagliardi, Susanna Zucca, Maddalena Arigoni, Marta Giannini, Maria Garofalo, Valentina Fantini, Orietta Pansarasa, Micol Avenali, Matteo Cotta Ramusino, Luca Diamanti, Brigida Minafra, Giulia Perini, Roberta Zangaglia, Alfredo Costa, Mauro Ceroni, Raffaele A. Calogero, Cristina Cereda
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
ObjectivesThere is a lack of effective biomarkers for neurodegenerative diseases (NDs) such as Alzheimer's disease (AD), Parkinson's disease (PD), amyotrophic lateral sclerosis (ALS), and frontotemporal dementia. Extracellular vesicle (EV) RNA cargo
Externí odkaz:
https://doaj.org/article/f8553c4ef248406a902687b6a84b128f
Autor:
Marta Lancione, Matteo Cencini, Mauro Costagli, Graziella Donatelli, Michela Tosetti, Giulia Giannini, Roberta Zangaglia, Giovanna Calandra-Buonaura, Claudio Pacchetti, Pietro Cortelli, Mirco Cosottini
Publikováno v:
NeuroImage: Clinical, Vol 34, Iss , Pp 102989- (2022)
The non-invasive quantification of iron stores via Quantitative Susceptibility Mapping (QSM) could play an important role in the diagnosis and the differential diagnosis of atypical Parkinsonisms. However, the susceptibility (χ) values measured via
Externí odkaz:
https://doaj.org/article/54eea552efec4250b75121bc7579e4bc
Autor:
Ilaria Palmieri, Marialuisa Valente, Lisa Maria Farina, Simone Gana, Brigida Minafra, Roberta Zangaglia, Orietta Pansarasa, Daisy Sproviero, Alfredo Costa, Claudio Pacchetti, Anna Pichiecchio, Stella Gagliardi, Cristina Cereda
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 8, p 3870 (2021)
Cerebral amyloid angiopathy (CAA) is a cerebrovascular disorder caused by the deposition of amyloid beta-peptide (Aβ) aggregates. Aβ aggregates lead to vessel rupture and intracerebral hemorrhages, detected by magnetic resonance imaging (MRI). Pres
Externí odkaz:
https://doaj.org/article/ff47e929f71d4e789f9b5e12ba877c29
Autor:
Daisy Sproviero, Stella Gagliardi, Susanna Zucca, Maddalena Arigoni, Marta Giannini, Maria Garofalo, Martina Olivero, Michela Dell’Orco, Orietta Pansarasa, Stefano Bernuzzi, Micol Avenali, Matteo Cotta Ramusino, Luca Diamanti, Brigida Minafra, Giulia Perini, Roberta Zangaglia, Alfredo Costa, Mauro Ceroni, Nora I. Perrone-Bizzozero, Raffaele A. Calogero, Cristina Cereda
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 5, p 2737 (2021)
Identifying biomarkers is essential for early diagnosis of neurodegenerative diseases (NDs). Large (LEVs) and small extracellular vesicles (SEVs) are extracellular vesicles (EVs) of different sizes and biological functions transported in blood and th
Externí odkaz:
https://doaj.org/article/4bb11436982c45278c69e0151e30d892
Autor:
Silvia Cerri, Cristina Ghezzi, Gerardo Ongari, Stefania Croce, Micol Avenali, Roberta Zangaglia, Donato A. Di Monte, Enza Maria Valente, Fabio Blandini
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 4, p 2215 (2021)
Heterozygous mutations in the GBA gene, encoding the lysosomal enzyme glucocerebrosidase (GCase), are the strongest known genetic risk factor for Parkinson’s disease (PD). The molecular mechanisms underlying the increased PD risk and the variable p
Externí odkaz:
https://doaj.org/article/52c40c1c184842408f263b511aae77f4
Autor:
Giulia Ambrosi, Cristina Ghezzi, Roberta Zangaglia, Giovanna Levandis, Claudio Pacchetti, Fabio Blandini
Publikováno v:
Neurobiology of Disease, Vol 82, Iss , Pp 235-242 (2015)
Heterozygous mutations in GBA1 gene, encoding for lysosomal enzyme glucocerebrosidase (GCase), are a major risk factor for sporadic Parkinson's disease (PD). Defective GCase has been reported in fibroblasts of GBA1-mutant PD patients and pharmacologi
Externí odkaz:
https://doaj.org/article/0c9263ad7acd43849db15d4f02295f00
Autor:
Silvia Cerri, Cristina Ghezzi, Maria Sampieri, Francesca Siani, Micol Avenali, Gianluca Dornini, Roberta Zangaglia, Brigida Minafra, Fabio Blandini
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2018)
Intensive research efforts in the field of Parkinson’s disease (PD) are focusing on identifying reliable biomarkers which possibly help physicians in predicting disease onset, diagnosis, and progression as well as evaluating the response to disease
Externí odkaz:
https://doaj.org/article/11f8a271c3e248e0a7ae3013fff6862e
Autor:
Lucia Corrado, Fabiola De Marchi, Sara Tunesi, Gaia Donata Oggioni, Miryam Carecchio, Luca Magistrelli, Silvana Tesei, Giulio Riboldazzi, Alessio Di Fonzo, Clarissa Locci, Ilaria Trezzi, Roberta Zangaglia, Cristina Cereda, Sandra D’Alfonso, Corrado Magnani, Giacomo P. Comi, Giorgio Bono, Claudio Pacchetti, Roberto Cantello, Stefano Goldwurm, Cristoforo Comi
Publikováno v:
Frontiers in Neurology, Vol 9 (2018)
BackgroundAlpha-synuclein is a constituent of Lewy bodies and mutations of its gene cause familial Parkinson’s disease (PD). A previous study showed that a variant of the alpha-synuclein gene (SNCA), namely the 263 bp allele of Rep1 was associated
Externí odkaz:
https://doaj.org/article/774f3424aaa043409a9ea78888eb221a
Autor:
Gaia Giannicola, Manuela Rosa, Sara Marceglia, Emma Scelzo, Lorenzo Rossi, Domenico Servello, Claudia Menghetti, Claudio Pacchetti, Roberta Zangaglia, Marco Locatelli, Elena Caputo, Filippo Cogiamanian, Gianluca Ardolino, Sergio Barbieri, Alberto Priori
Publikováno v:
Neurosignals, Vol 21, Iss 1-2, Pp 89-98 (2012)
New adaptive systems for deep brain stimulation (DBS) could in the near future optimize stimulation settings online so as to achieve better control over the clinical fluctuations in Parkinson's disease (PD). Local field potentials (LFPs) recorded fro
Externí odkaz:
https://doaj.org/article/bbd3948f4a8c429285ac92162664302d
Autor:
Roberto Cilia, Emanuele Cereda, Marco Piatti, Andrea Pilotto, Luca Magistrelli, Nico Golfrè Andreasi, Salvatore Bonvegna, Elena Contaldi, Francesca Mancini, Gabriele Imbalzano, Rosa De Micco, Fabiana Colucci, Arianna Braccia, Gabriele Bellini, Francesco Brovelli, Roberta Zangaglia, Giulia Lazzeri, Maria Claudia Russillo, Enrica Olivola, Chiara Sorbera, Viviana Cereda, Patrizia Pinto, Patrizia Sucapane, Giorgio Gelosa, Mario Meloni, Francesca Pistoia, Maria Sessa, Margherita Canesi, Nicola Modugno, Claudio Pacchetti, Laura Brighina, Maria Teresa Pellecchia, Roberto Ceravolo, Mariachiara Sensi, Maurizio Zibetti, Cristoforo Comi, Alessandro Padovani, Anna L. Zecchinelli, Alessio Di Fonzo, Alessandro Tessitore, Francesca Morgante, Roberto Eleopra
Publikováno v:
Movement Disorders Clinical Practice. 10:625-635