Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Roberta T. Mettus"'
Widespread Fosfomycin Resistance in Gram-Negative Bacteria Attributable to the Chromosomal fosA Gene
Autor:
Ryota Ito, Mustapha M. Mustapha, Adam D. Tomich, Jake D. Callaghan, Christi L. McElheny, Roberta T. Mettus, Robert M. Q. Shanks, Nicolas Sluis-Cremer, Yohei Doi
Publikováno v:
mBio, Vol 8, Iss 4 (2017)
ABSTRACT Fosfomycin is a decades-old antibiotic which is being revisited because of its perceived activity against many extensively drug-resistant Gram-negative pathogens. FosA proteins are Mn2+ and K+-dependent glutathione S-transferases which confe
Externí odkaz:
https://doaj.org/article/800591cac5b2456d90b934759a38ffd9
Autor:
Yohei Doi, Mustapha M. Mustapha, Roberta T. Mettus, Alina Iovleva, Vaughn S. Cooper, Ryan K. Shields, Daria Van Tyne, Christi L. McElheny, A. William Pasculle
Publikováno v:
J Antimicrob Chemother
Background OXA-2 is a class D β-lactamase that confers resistance to penicillins, as well as narrow-spectrum cephalosporins. OXA-2 was recently reported to also possess carbapenem-hydrolysing activity. Here, we describe a KPC-2-encoding Klebsiella p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f1b9519b5600370503c5abf14db0ea8
https://doi.org/10.1093/jac/dkz183
https://doi.org/10.1093/jac/dkz183
Autor:
Janet S. Lee, Jennifer M. Bomberger, Hernán F. Peñaloza, Jill Zupetic, Yohei Doi, Joseph M. Pilewski, Roberta T. Mettus, Mei Hulver, Peter Jorth, William Bain, Mehdi Nouraie
Publikováno v:
Chest
Background Pseudomonas aeruginosa (PA) is a common cause of respiratory infection and morbidity. Pseudomonas elastase is an important virulence factor regulated by the lasR gene. Whether PA elastase activity is associated with worse clinical outcomes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a93e6720d8f7e4bee2c0e1c5b1af695
https://pubmed.ncbi.nlm.nih.gov/33878342
https://pubmed.ncbi.nlm.nih.gov/33878342
Autor:
Christi L. McElheny, Lee H. Harrison, Yohei Doi, Ryan K. Shields, Marissa P. Griffith, Daniel R. Evans, Ahmed Babiker, Roberta T. Mettus, Daria Van Tyne, Mohamed A. Hassan, Lloyd Clarke
Publikováno v:
Journal of Clinical Microbiology
Carbapenem-nonsusceptible Citrobacter spp. (CNSC) are increasingly recognized as health care-associated pathogens. Information regarding their clinical epidemiology, genetic diversity, and mechanisms of carbapenem resistance is lacking. We examined m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::302d65eefe91b3773d6d056cb8998596
https://doi.org/10.1128/jcm.00275-20
https://doi.org/10.1128/jcm.00275-20
Autor:
Mei Hulver, Yohei Doi, Christi L. McElheny, William Bain, Janet S. Lee, Yanyan Qu, Jill Zupetic, H.F. Peñaloza Cerda, Mehdi Nouraie, Roberta T. Mettus, Rebecca S. DeSensi
Publikováno v:
D102. BACTERIAL INFECTIONS: IMMUNITY AND BASIC MECHANISMS.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23ccc23b1a92cdb4cdb47cdeb3430ab9
https://doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a7732
https://doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a7732
Autor:
Daria Van Tyne, Lee H. Harrison, Roberta T. Mettus, Christi L. McElheny, Yohei Doi, Daniel R. Evans, Marissa P. Griffith, Lloyd Clarke, Ryan K. Shields, Ahmed Babiker, Mohamed A. Hassan
Carbapenem-non-susceptible Citrobacter spp. (CNSC) are increasingly recognized as healthcare-associated pathogens. Information regarding their clinical epidemiology, genetic diversity, and mechanisms of carbapenem resistance is lacking. We examined m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89a5cc980cd607a6d033f41199bbef68
Autor:
Ryan K. Shields, Gregory B Tallman, Yohei Doi, Roberta T. Mettus, Romney M. Humphries, Peera Hemarajata, Morgan Hakki, James S. Lewis
Publikováno v:
Clinical Infectious Diseases. 68:2045-2052
Background In Pseudomonas aeruginosa, fluoroquinolone exposure promotes resistance to carbapenems through upregulation of efflux pumps and transcriptional downregulation of the porin OprD. Evidence of this effect among hematologic malignancy (HM) pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df1b126d758ccfbc3a6f9b0b0162fd76
https://doi.org/10.1093/cid/ciy825
https://doi.org/10.1093/cid/ciy825
Autor:
Mustapha M. Mustapha, Marissa P. Griffith, Christi L. McElheny, Alina Iovleva, Ryan K. Shields, A. William Pasculle, Yohei Doi, Vaughn S. Cooper, Roberta T. Mettus
Publikováno v:
Antimicrob Agents Chemother
OXA-232 is an OXA-48-group class D β-lactamase that hydrolyzes expanded-spectrum cephalosporins and carbapenems at low levels. Clinical strains producing OXA-232 are sometimes susceptible to carbapenems, making it difficult to identify them in the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::495ac7666c9267d634c7f7ecd04539fa
https://doi.org/10.1128/aac.01335-19
https://doi.org/10.1128/aac.01335-19
Autor:
Yohei Doi, Robert K. Ernst, Bin Li, Christi L. McElheny, Christopher W. Marshall, Vaughn S. Cooper, Mustapha M. Mustapha, Roberta T. Mettus, Marissa P Pacey
Publikováno v:
Journal of Antimicrobial Chemotherapy. 73:2952-2959
BACKGROUND: Acinetobacter baumannii is a healthcare-associated pathogen with high rates of carbapenem resistance. Colistin is now routinely used for treatment of infections by this pathogen. However, colistin use has been associated with development
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dd6eaa05f8c5dc8a5ec181b302abfb4
https://doi.org/10.1093/jac/dky290
https://doi.org/10.1093/jac/dky290
Publikováno v:
Journal of Antimicrobial Chemotherapy. 73:373-376
Background fosA3 is the most commonly reported plasmid-mediated fosfomycin resistance gene among Enterobacteriaceae. Objectives To identify the origin of fosA3. Methods The chromosome of Kluyvera georgiana clinical strain YDC799 was fully sequenced w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7748b5b55f8f02f60e28efc73e038c77
https://doi.org/10.1093/jac/dkx389
https://doi.org/10.1093/jac/dkx389