Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Roberta Sgariglia"'
Autor:
Pasquale Pisapia, Francesco Pepe, Antonino Iaccarino, Roberta Sgariglia, Mariantonia Nacchio, Gianluca Russo, Gianluca Gragnano, Elalah Mosaieby, Giancarlo Troncone, Umberto Malapelle
Publikováno v:
Journal of Molecular Pathology, Vol 2, Iss 3, Pp 241-254 (2021)
Lung cancer is the leading cause of cancer death worldwide. Despite the emergence of highly effective targeted therapies, up to 30% of advanced stage non-small cell lung cancer (NSCLC) patients do not undergo tissue molecular testing because of scarc
Externí odkaz:
https://doaj.org/article/b04704275452439fa15fd6259557e6fc
Autor:
Claudio Bellevicine, Roberta Sgariglia, Mariantonia Nacchio, Caterina De Luca, Pasquale Pisapia, Francesco Pepe, Giancarlo Troncone
Publikováno v:
Journal of Molecular Pathology, Vol 2, Iss 3, Pp 233-240 (2021)
Molecular testing has acquired a relevant role for diagnostic and prognostic stratification of indeterminate thyroid nodules. Besides the available commercial solutions marketed in the United States, various local testing strategies have been develop
Externí odkaz:
https://doaj.org/article/ffacc5d5e5924307bd42a856cec14987
Autor:
Pasquale Pisapia, Francesco Pepe, Antonino Iaccarino, Roberta Sgariglia, Mariantonia Nacchio, Floriana Conticelli, Maria Salatiello, Rossella Tufano, Gianluca Russo, Gianluca Gragnano, Ilaria Girolami, Albino Eccher, Umberto Malapelle, Giancarlo Troncone
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Molecular cytopathology is a rapidly evolving field embracing both conventional microscopy and molecular pathology. Its growing popularity stems from the fact that in many types of advanced cancers, including non small cell lung cancer (NSCLC), cytol
Externí odkaz:
https://doaj.org/article/197214dfb4c04874966ee0ec43e3ab09
Autor:
Umberto Malapelle, Francesco Pepe, Pasquale Pisapia, Roberta Sgariglia, Mariantonia Nacchio, Caterina De Luca, Rosanna Lacalamita, Stefania Tommasi, Rosamaria Pinto, Grazia Palomba, Giuseppe Palmieri, Davide Vacirca, Massimo Barberis, Irene Bottillo, Paola Grammatico, Lucia Rosalba Grillo, Valerio Costa, Riccardo Smeraglio, Dario Bruzzese, Giancarlo Troncone
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Background: Next-generation sequencing (NGS) needs to be validated and standardized to ensure that cancer patients are reliably selected for target treatments. In Italy, NGS is performed in several institutions and harmonization of wet and dry proced
Externí odkaz:
https://doaj.org/article/1fc67acac42f4a7d8cd333500eda0b27
Autor:
Umberto Malapelle, Paola Parente, Francesco Pepe, Caterina De Luca, Pasquale Pisapia, Roberta Sgariglia, Mariantonia Nacchio, Gianluca Gragnano, Gianluca Russo, Floriana Conticelli, Claudio Bellevicine, Elena Vigliar, Antonino Iaccarino, Claudia Covelli, Mariangela Balistreri, Celeste Clemente, Giovanni Perrone, Angela Danza, Fabio Scaramuzzi, Matteo Fassan, Giancarlo Troncone, Paolo Graziano
Publikováno v:
Cells, Vol 10, Iss 8, p 1878 (2021)
Immune-checkpoint inhibitors (ICIs) play a key role in the treatment of advanced stage colorectal cancer (CRC) patients featuring a deficient DNA mismatch repair (dMMR) system or a high microsatellite instability (MSI-H) profile. However, beyond the
Externí odkaz:
https://doaj.org/article/544f7bbcbfa2417aa5d28f9107fd3d82
Autor:
Pierlorenzo Pallante, Umberto Malapelle, Mariantonia Nacchio, Roberta Sgariglia, Domenico Galati, Ludovica Capitelli, Serena Zanotta, Mario Galgani, Erica Piemonte, Alessandro Sanduzzi Zamparelli, Gaetano Rea, Marialuisa Bocchino
Publikováno v:
Diagnostics, Vol 11, Iss 7, p 1202 (2021)
Liquid biopsy, which allows the isolation of circulating cell-free (ccf) DNA from blood, is an emerging noninvasive tool widely used in oncology for diagnostic and prognosis purposes. Previous data have shown that serum cfDNA discriminates idiopathic
Externí odkaz:
https://doaj.org/article/5a9792d47bfd4c9aac2a69b13b09e9ee
Autor:
Pasquale Pisapia, Francesco Pepe, Antonino Iaccarino, Roberta Sgariglia, Mariantonia Nacchio, Gianluca Russo, Gianluca Gragnano, Umberto Malapelle, Giancarlo Troncone
Publikováno v:
Cells, Vol 9, Iss 12, p 2549 (2020)
Gain-of-function of V-Raf Murine Sarcoma Viral Oncogene Homolog B (BRAF) is one of the most frequent oncogenic mutations in numerous cancers, including thyroid papillary carcinoma, melanoma, colon, and lung carcinomas, and to a lesser extent, ovarian
Externí odkaz:
https://doaj.org/article/a41c64bdd5054caaba523f512c824b94
Autor:
Francesco Pepe, Antonino Iaccarino, Roberta Sgariglia, Gianluca Russo, G. Troncone, Umberto Malapelle, Mariantonia Nacchio, Elalah Mosaieby, Pasquale Pisapia, Gianluca Gragnano
Publikováno v:
Journal of Molecular Pathology, Vol 2, Iss 21, Pp 241-254 (2021)
Lung cancer is the leading cause of cancer death worldwide. Despite the emergence of highly effective targeted therapies, up to 30% of advanced stage non-small cell lung cancer (NSCLC) patients do not undergo tissue molecular testing because of scarc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f536715641917e3d0d59035cc7c31437
https://www.mdpi.com/2673-5261/2/3/21
https://www.mdpi.com/2673-5261/2/3/21
Autor:
Elena Vigliar, Gianluca Russo, Ilaria Girolami, Umberto Malapelle, Claudio Bellevicine, Pasquale Pisapia, Albino Eccher, Giancarlo Troncone, Francesco Pepe, Mariantonia Nacchio, Roberta Sgariglia, Floriana Conticelli
Publikováno v:
Cytopathology
The application of next generation sequencing (NGS) technology to cytological samples has significantly modified molecular cytopathology practice. Cytological samples represent a valid source of high‐quality DNA for NGS analysis, especially for pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5b7600cc313325c216bd51d42ebb946
https://doi.org/10.1111/cyt.12974
https://doi.org/10.1111/cyt.12974
Autor:
Caterina De Luca, Domenico Salvatore, Mariantonia Nacchio, Giancarlo Troncone, Ilaria Migliatico, Umberto Malapelle, Antonino Iaccarino, Pasquale Pisapia, Elena Vigliar, Stefania Masone, Claudio Bellevicine, Roberta Sgariglia
Publikováno v:
Journal of Clinical Pathology. 75:465-471
AimsIn thyroid cytopathology, the undetermined diagnostic categories still pose diagnostic challenges. Although next-generation sequencing (NGS) is a promising technique for the molecular testing of thyroid fine-needle aspiration (FNA) specimens, acc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cb18bee72b5c13ad06d3f66de947f57
https://doi.org/10.1136/jclinpath-2021-207429
https://doi.org/10.1136/jclinpath-2021-207429