Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Roberta Schulte"'
Publikováno v:
eLife, Vol 9 (2020)
Vascular dysfunctions are a common feature of multiple age-related diseases. However, modeling healthy and pathological aging of the human vasculature represents an unresolved experimental challenge. Here, we generated induced vascular endothelial ce
Externí odkaz:
https://doaj.org/article/f8f6f79763544625929e767fdf5e9f32
Autor:
Jason G. Fleischer, Roberta Schulte, Hsiao H. Tsai, Swati Tyagi, Arkaitz Ibarra, Maxim N. Shokhirev, Ling Huang, Martin W. Hetzer, Saket Navlakha
Publikováno v:
Genome Biology, Vol 19, Iss 1, Pp 1-8 (2018)
Abstract Biomarkers of aging can be used to assess the health of individuals and to study aging and age-related diseases. We generate a large dataset of genome-wide RNA-seq profiles of human dermal fibroblasts from 133 people aged 1 to 94 years old t
Externí odkaz:
https://doaj.org/article/12dd11bf4565406cae4c9853a19596fb
Publikováno v:
eLife, Vol 8 (2019)
The inner nuclear membrane (INM) is a subdomain of the endoplasmic reticulum (ER) that is gated by the nuclear pore complex. It is unknown whether proteins of the INM and ER are degraded through shared or distinct pathways in mammalian cells. We appl
Externí odkaz:
https://doaj.org/article/4bca6c5750a6477bb1500ce8c0678172
Publikováno v:
PLoS ONE, Vol 3, Iss 4, p e2061 (2008)
We present a miniaturized pull-down method for the detection of protein-protein interactions using standard affinity chromatography reagents. Binding events between different proteins, which are color-coded with quantum dots (QDs), are visualized on
Externí odkaz:
https://doaj.org/article/9ff43c6f4bb845bc87b2606e2e574212
Publikováno v:
eLife, Vol 9 (2020)
eLife
eLife
Vascular dysfunctions are a common feature of multiple age-related diseases. However, modeling healthy and pathological aging of the human vasculature represents an unresolved experimental challenge. Here, we generated induced vascular endothelial ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3808a0e9cdb72e2f1c7214c0ade3a503
https://pubmed.ncbi.nlm.nih.gov/32896271
https://pubmed.ncbi.nlm.nih.gov/32896271
Autor:
Geoffrey M. Wahl, Martin W. Hetzer, Roberta Schulte, Nikki K. Lytle, Simone Bersini, Ling Huang
Publikováno v:
Life Science Alliance
This study highlights the role of Nup93-chromatin interactions in driving triple-negative breast cancer propagation through modulation of the actin cytoskeleton, cell migration and proliferation.
Nucleoporin 93 (Nup93) expression inversely corre
Nucleoporin 93 (Nup93) expression inversely corre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6184c47f0b8e279ccf246a0c6f2b4ff8
https://pubmed.ncbi.nlm.nih.gov/31959624
https://pubmed.ncbi.nlm.nih.gov/31959624
Publikováno v:
eLife, Vol 8 (2019)
eLife
eLife
The inner nuclear membrane (INM) is a subdomain of the endoplasmic reticulum (ER) that is gated by the nuclear pore complex. It is unknown whether proteins of the INM and ER are degraded through shared or distinct pathways in mammalian cells. We appl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdb5a2bc69eec55f7e2828b5158cacd9
Autor:
Ling Huang, Martin W. Hetzer, Saket Navlakha, Swati Tyagi, Arkaitz Ibarra, Jason G. Fleischer, Hsiao H. Tsai, Maxim N. Shokhirev, Roberta Schulte
Publikováno v:
Genome Biology
Genome Biology, Vol 19, Iss 1, Pp 1-8 (2018)
Genome Biology, Vol 19, Iss 1, Pp 1-8 (2018)
Biomarkers of aging can be used to assess the health of individuals and to study aging and age-related diseases. We generate a large dataset of genome-wide RNA-seq profiles of human dermal fibroblasts from 133 people aged 1 to 94 years old to test wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::777fc22f1dd05969cadef3ed2f6ae27a
https://pubmed.ncbi.nlm.nih.gov/30567591
https://pubmed.ncbi.nlm.nih.gov/30567591