Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Roberta Schellino"'
Autor:
Roberta Schellino, Dario Besusso, Roberta Parolisi, Gabriela B. Gómez-González, Sveva Dallere, Linda Scaramuzza, Marta Ribodino, Ilaria Campus, Paola Conforti, Malin Parmar, Marina Boido, Elena Cattaneo, Annalisa Buffo
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-21 (2023)
Abstract Background Huntington’s disease (HD) is a motor and cognitive neurodegenerative disorder due to prominent loss of striatal medium spiny neurons (MSNs). Cell replacement using human embryonic stem cells (hESCs) derivatives may offer new the
Externí odkaz:
https://doaj.org/article/f71569f50089476dbb34ca55c6b023b8
Autor:
Margherita Tassan Mazzocco, Valentina Murtaj, Daniel Martins, Roberta Schellino, Angela Coliva, Elisa Toninelli, Alessandro Vercelli, Federico Turkheimer, Sara Belloli, Rosa Maria Moresco
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-17 (2023)
Abstract Background One intrastriatal administration of quinolinic acid (QA) in rats induces a lesion with features resembling those observed in Huntington’s disease. Our aim is to evaluate the effects of the cysteinyl leukotriene receptor antagoni
Externí odkaz:
https://doaj.org/article/974ef2f31bcc4b358530cb0116958ea0
The Dual Nature of Onuf’s Nucleus: Neuroanatomical Features and Peculiarities, in Health and Disease
Publikováno v:
Frontiers in Neuroanatomy, Vol 14 (2020)
Onuf’s nucleus is a small group of neurons located in the ventral horns of the sacral spinal cord. The motor neurons (MNs) of Onuf’s nucleus innervate striated voluntary muscles of the pelvic floor and are histologically and biochemically compara
Externí odkaz:
https://doaj.org/article/062a4842fdc9430c96c9258d9a7b412e
Autor:
Marina Boido, Olena Butenko, Consuelo Filippo, Roberta Schellino, Jan W Vrijbloed, Ruggero G Fariello, Alessandro Vercelli
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0228653 (2020)
Current efforts to improve muscle performance are focused on muscle trophism via inhibition of the myostatin pathway: however they have been unsuccessful in the clinic to date. In this study, a novel protein has been created by combining the soluble
Externí odkaz:
https://doaj.org/article/806d02b576494fb286821db5fb75f973
Autor:
Bart C. Jongbloets, Suzanne Lemstra, Roberta Schellino, Mark H. Broekhoven, Jyoti Parkash, Anita J. C. G. M. Hellemons, Tianyi Mao, Paolo Giacobini, Henriette van Praag, Silvia De Marchis, Geert M. J. Ramakers, R. Jeroen Pasterkamp
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-17 (2017)
The functions of semaphorins in the adult brain are poorly understood. Here the authors show that Sema7A carries out stage-specific functions in the adult hippocampus via differential receptor usage; in progenitor cells, Sema7A inhibits proliferation
Externí odkaz:
https://doaj.org/article/d30daa3df5364f93beb8a981d0a1cc8e
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
Spinal muscular atrophy (SMA) is a severe neurodegenerative disorder that occurs in early childhood. The disease is caused by the deletion/mutation of the survival motor neuron 1 (SMN1) gene resulting in progressive skeletal muscle atrophy and paraly
Externí odkaz:
https://doaj.org/article/644dd147741b40229fb74764c7daca15
Autor:
Livio Oboti, Sara Trova, Roberta Schellino, Marilena Marraudino, Natalie R. Harris, Olubukola M. Abiona, Mojca Stampar, Weihong Lin, Paolo Peretto
Publikováno v:
Frontiers in Neuroanatomy, Vol 11 (2017)
The vomeronasal system (VNS) is specialized in the detection of salient chemical cues triggering social and neuroendocrine responses. Such responses are not always stereotyped, instead, they vary depending on age, sex, and reproductive state, yet the
Externí odkaz:
https://doaj.org/article/f3298653db804a2d887d4678b571a61b
Publikováno v:
Neural Plasticity, Vol 2014 (2014)
Adult neurogenesis is a striking form of structural plasticity that adapts the brain to the changing world. Accordingly, new neuron production is involved in cognitive functions, such as memory, learning, and pattern separation. Recent data in rodent
Externí odkaz:
https://doaj.org/article/aa1029f58b694b8f9f71316845516428
Autor:
Marina Boido, Iacopo Gesmundo, Anna Caretto, Francesca Pedrolli, Roberta Schellino, Sheila Leone, Renzhi Cai, Wei Sha, Ezio Ghigo, Andrew V. Schally, Alessandro Vercelli, Riccarda Granata
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 120(2)
Spinal muscular atrophy (SMA) is a severe autosomal recessive neuromuscular disease affecting children and young adults, caused by mutations of the survival motor neuron 1 gene ( SMN1 ). SMA is characterized by the degeneration of spinal alpha motor
Autor:
Dario Besusso, Roberta Schellino, Roberta Parolisi, Gabriela Gómez-González, Sveva Dallere, Linda Scaramuzza, Marta Ribodino, Ilaria Campus, Paola Conforti, Malin Parmar, Marina Boido, Elena Cattaneo, Annalisa Buffo
Publikováno v:
I: Experimental therapeutics – preclinical.