Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Roberta Raeder"'
Autor:
Roberta Raeder, Bhaskar V. S. Kallakury, Dennis W. Metzger, Stephen F. Badylak, Christine E. Sheehan
Publikováno v:
Transplant Immunology. 10:15-24
Naturally occurring antibodies to the galactose alpha1,3 galactose (alpha gal) epitope expressed on xenogeneic grafts are a major barrier to organ transplantation in humans. Porcine small intestinal submucosa (SIS) expresses the alpha gal epitope and
Autor:
Dennis W. Metzger, Stephen F. Badylak, Christine E. Sheehan, Roberta Raeder, Timothy B. Mcpherson, Amy J Allman, Lisa C. Merrill, Bhaskar V. S. Kallakury
Publikováno v:
Transplantation. 71:1631-1640
Background Porcine small intestinal submucosa (SIS) is an acellular, naturally derived extracellular matrix (ECM) that has been used for tissue remodeling and repair in numerous xenotransplantations. Although a vigorous immune response to xenogeneic
IL-12-mediated increases in protection elicited by pneumococcal and meningococcal conjugate vaccines
Autor:
David E. Briles, Dennis W. Metzger, Bernard P. Arulanandam, M. A. Julie Westerink, Roberta Raeder, Renee M. Buchanan
Publikováno v:
Vaccine. 19:2020-2028
Interleukin-12 (IL-12) may be a beneficial adjuvant for augmenting vaccine efficacy against encapsulated bacteria such as Streptococcus pneumoniae and Neisseria meningitidis since it can stimulate production of interferon-gamma (IFN-gamma) and secret
Publikováno v:
Research in Microbiology. 149:539-548
Previous studies of recent clinical isolates of serotype M1 group A streptococci indicated that they display two patterns of non-immune human IgG subclass binding reactivity associated with their M1 protein. One group reacted with all four IgG subcla
Publikováno v:
Infection and Immunity. 62:2104-2107
Analysis of group A streptococcal immunoglobulin G (IgG)-binding protein reactivity with different human IgG3-myeloma proteins provided evidence for at least two functional forms of these molecules. Representative IgG3-binding molecules were isolated
Publikováno v:
Infection and Immunity. 62:1336-1347
An emm-like gene (emmL) and a fcrA gene from group A streptococcal strain 64/14 (emmL64/14 and fcrA64/14) were amplified by PCR and force cloned into the heat-inducible expression vector pJLA 602. The emmL gene encoded a recombinant protein that boun
Autor:
Michael D.P. Boyle, Roberta Raeder
Publikováno v:
Infection and Immunity. 61:3696-3702
Expression of immunoglobulin G (IgG)-binding proteins on group A streptococcus strain 64 was monitored on bacteria subjected to sequential passage in human blood. After approximately 10 cycles through human blood, strain 64 demonstrated enhanced leve
Autor:
Michael D.P. Boyle, Roberta Raeder
Publikováno v:
Infection and Immunity. 61:1378-1384
In this study, we developed a mouse model of skin infection to test the association between expression of immunoglobulin-binding proteins by and infectivity of group A streptococci. Group A streptococci capable of crossing tissue barriers and establi
Autor:
Roberta Raeder, Michael D.P. Boyle
Publikováno v:
ImmunoMethods. 2:41-53
Methods for analyzing the functional heterogeneity of type II IgG-binding proteins expressed by group A streptococci are described. Evidence for two major antigenic classes of type II IgG-binding proteins is presented. Heterogeneity in functional bin
Autor:
Roberta Raeder, Michael D.P. Boyle
Publikováno v:
Journal of Immunological Methods. 138:201-209
A simple, rapid two-stage competitive binding radioimmunoassay is described for detecting rheumatoid factor-like antibodies in the serum of chickens immunized with bacterial immunoglobulin binding proteins. The assay could be adapted to determine the