Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Roberta R. Pollock"'
Publikováno v:
Frontiers in Public Health, Vol 8 (2020)
Immunology is a fascinating and extremely complex field, with natural connections to many disciplines both within STEM and beyond. Teaching an undergraduate course in immunology therefore provides both opportunities and challenges. Significant challe
Externí odkaz:
https://doaj.org/article/a7a31b9661f5450085b6c977a52851a2
Publikováno v:
Frontiers in Public Health, Vol 8 (2020)
Frontiers in Public Health
Frontiers in Public Health
Immunology is a fascinating and extremely complex field, with natural connections to many disciplines both within STEM and beyond. Teaching an undergraduate course in immunology therefore provides both opportunities and challenges. Significant challe
Autor:
Jean-Luc Teillaud, Catherine Desaymard, Angela M. Giusti, Barbara Haseltine, Roberta R. Pollock, Dale E. Yelton, Donald J. Zack, Matthew D. Scharff
Publikováno v:
Biotechnology & Biological Frontiers ISBN: 9780429050329
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1bb598c4146035a45f83f453266660b6
https://doi.org/10.4324/9780429050329-24
https://doi.org/10.4324/9780429050329-24
Publikováno v:
Annals of the New York Academy of Sciences. 764:183-186
Publikováno v:
The Journal of Immunology. 166:2617-2626
Aging has been associated with intrinsic changes of the humoral immune response, which may lead to an increased occurrence of autoimmune disorders and pathogenic susceptibility. The transcription factor Pax-5 is a key regulator of B cell development.
Autor:
Susan E. Prockop, Leonore A. Herzenberg, Garry P. Nolan, S C Li, Roberta R. Pollock, Frederick W. Alt, G D Yancopoulos
Publikováno v:
Molecular and Cellular Biology. 10:1697-1704
We describe two retroviral vector-based recombination substrate systems designed to assay for lymphoid VDJ recombinase activity in cultured cells. Both substrates incorporate a constitutive dominant marker gene (the simian virus promoter-driven neo g
Autor:
Takao Kodera, Tracy L. McGaha, Constantin A. Bona, Hilde Cheroute, Patty Zwolo, Dorel L. Radu, Cristina Stoica, Roberta R. Pollock
Publikováno v:
Genes to cells : devoted to molecularcellular mechanisms. 9(11)
Somatic mutation of immunoglobulin (Ig) genes plays an important role in generating antibody diversity. The frequency of somatic mutation appears to vary throughout life. However, this process has been difficult to study in vivo because the DNA in an
Autor:
Hector Arrieta, Roberta R. Pollock, Karen Molinder, Kaleo Ede, Patty Zwollo, Stephen Desiderio
Publikováno v:
The Journal of biological chemistry. 272(15)
The transcription factor Pax-5 is expressed during the early stages of B-cell differentiation and influences the expression of several B-cell-specific genes. In addition to the existing isoform (Pax-5, which we have named Pax-5a), we have isolated th
Autor:
Roberta R. Pollock, Ruud K. B. Schuurman, Jeffrey E. Berman, Katherine G. Nickerson, Jeremy E. Barth, Frederick W. Alt, Daniel M. Knowles, Leonard Chess
Publikováno v:
European journal of immunology. 21(5)
Preferential usage of JH-proximal VH genes has been demonstrated in immature murine B cell repertoires. To determine whether this phenomenon is also evident in human repertoires, we studied utilization of VH6, the most JH-proximal human VH gene. Exam
Autor:
Barbara K. Birshtein, Matthew D. Scharff, Roberta R. Pollock, Joshua P. Metlay, Deborah L. French
Publikováno v:
European journal of immunology. 20(9)
The metabolism of IgG immunoglobulins in the body is tightly regulated in order to maintain their intravascular concentration. Different subclasses may have different intravascular half-lives, and in the mouse, passively administered IgG2b disappears