Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Roberta Pachera"'
Autor:
Sara Rossi, Paolo Stabile, Jason W. B. Cooke, Gilles Laval, Paola Russo, Roberta Pachera, Ramona Moretti, Pieter Westerduin, Zadeo Cimarosti, Nicola Giubellina, Francesco Tinazzi, William Maton
Publikováno v:
Organic Process Research & Development. 15:1287-1296
1-(3-{2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)-2-imidazolidinone, 1, was identified as a potential drug for the treatment of depression and anxiety. Herein is described the work carried out to select the manufacturing route and the pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f192f5af1e4d746b5fb7e9edfa63ad2c
https://doi.org/10.1021/op200140v
https://doi.org/10.1021/op200140v
Autor:
William Maton, Fernando Bravo, Paolo Stabile, Daniele Andreotti, Arnaldo Nalin, Simone Spada, Roberto Profeta, Alcide Perboni, Federica Stazi, Damiano Castoldi, Anna Mingardi, Stefano Provera, Emanuele Miserazzi, Nicola Giubellina, Mario Mattioli, Roberta Pachera, Pieter Westerduin, Arianna Ribecai, Simon M. Bryant, Lucilla Turco, Angelo M. Manzo
Publikováno v:
Organic Process Research & Development. 14:1239-1247
An efficient scalable route to synthesize the enantiomerically pure tert-butyl-(1R,4S,6R)-4-(hydroxymethyl)-3-azabicyclo[4.1.0]heptane-3-carboxylate is described. Compared to the original routes, significant improvements were made by using an innovat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb19119ea9299a9302fec3bb306f634d
https://doi.org/10.1021/op100164v
https://doi.org/10.1021/op100164v
Preparation of the Key Intermediate in the Synthesis of GV143253A: The Anti-MRSA/E Injectable Trinem
Publikováno v:
Organic Process Research & Development. 6:597-605
GV143253A is a broad-spectrum injectable β-lactam belonging to the class of trinem antibiotics. A key intermediate (3S,4R)-3-[(1R)-1-(tert-butyldimethyl- silyloxy)ethyl]-4-[-(6‘R)-2‘-[(E)-(pyrid-4yl)methylene]-1‘-oxocyclohex-6‘-yl]azetidin-2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40a3a269a8f6fd08fab54c435f073e8d
https://doi.org/10.1021/op020024l
https://doi.org/10.1021/op020024l
Autor:
Roberto Camerini, Roberta Pachera, Daniele Donati, Mauro Panunzio, Carla Marchioro, Andrea Mazzoni
Publikováno v:
Tetrahedron: Asymmetry. 8:15-17
Pseudomonas fluorescens lipase (PFL) was used as catalyst for enzymatic resolution of 1-ethoxycarbonyl-2-hydroxy-cyclohexane. The resulting ester was used for the total synthesis of the novel enantiomerically pure 10-ethyl trinem.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af8777798be5e797b12a37a3ce06d7ee
https://doi.org/10.1016/s0957-4166(96)00489-2
https://doi.org/10.1016/s0957-4166(96)00489-2
Autor:
Zadeo Cimarosti, Nicola Giubellina, Paolo Stabile, Gilles Laval, Francesco Tinazzi, William Maton, Roberta Pachera, Paola Russo, Ramona Moretti, Sara Rossi, Jason W. B. Cooke, Pieter Westerduin
Publikováno v:
Organic Process Research & Development; Nov2011, Vol. 15 Issue 6, p1287-1296, 10p