Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Roberta Ottria"'
Publikováno v:
Microorganisms, Vol 12, Iss 8, p 1582 (2024)
Probiotics are “live microorganisms which, when administered in adequate amount, confer health benefits on the host”. They can be found in certain foods like yogurt and kefir and in dietary supplements. The introduction of bacterial derivatives h
Externí odkaz:
https://doaj.org/article/422cd7f496284233aa57f8dfeac69bbf
Autor:
Chiara Mandò, Sara Castiglioni, Chiara Novielli, Gaia Maria Anelli, Anaïs Serati, Francesca Parisi, Chiara Lubrano, Monica Zocchi, Roberta Ottria, Matteo Giovarelli
Publikováno v:
Antioxidants, Vol 13, Iss 7, p 858 (2024)
Maternal obesity has been associated with short- and long-term risks of pregnancy-perinatal adverse events, possibly due to alterations of placental mitochondrial bioenergetics. However, several detrimental mechanisms occurring in the placentas of wo
Externí odkaz:
https://doaj.org/article/9025a9516d3942efb9f4c44dee380828
Publikováno v:
Molecules, Vol 27, Iss 16, p 5190 (2022)
A simple and practical synthesis of 2-arachidonoyl glycerol (2-AG), an endogenous agonist for cannabinoid receptors, based on a two-step enzymatic process and a chemical coupling, was achieved with a good yield and negligible amount of the isomerizat
Externí odkaz:
https://doaj.org/article/a3aa318aec9240ccb297434ce90e6a60
Autor:
Silvana Casati, Paola Rota, Pietro Allevi, Alessandra Mingione, Roberta Ottria, Pierangela Ciuffreda
Publikováno v:
Molecules, Vol 26, Iss 21, p 6447 (2021)
In the last two years, nucleosides analogues, a class of well-established bioactive compounds, have been the subject of renewed interest from the scientific community thanks to their antiviral activity. The COVID-19 global pandemic, indeed, spread li
Externí odkaz:
https://doaj.org/article/410d6199b61543a1bed3d6d552438dd5
Autor:
Sara Casati, Chiara Giannasi, Mauro Minoli, Stefania Niada, Alessandro Ravelli, Ilaria Angeli, Veronica Mergenthaler, Roberta Ottria, Pierangela Ciuffreda, Marica Orioli, Anna T. Brini
Publikováno v:
Biomolecules, Vol 10, Iss 9, p 1302 (2020)
Changes in lipid metabolism are involved in several pathological conditions, such as cancer. Among lipids, eicosanoids are potent inflammatory mediators, synthesized from polyunsaturated fatty acids (PUFAs), which coexist with other lipid-derived one
Externí odkaz:
https://doaj.org/article/802b937cb5e84299b76c420e081688ba
Publikováno v:
Molecules, Vol 25, Iss 9, p 2019 (2020)
The use of doping in sports is a global problem that affects athletes around the world. Among the different methods developed to detect doping agents in biological samples, there are antibody-based methods that need an appropriate hapten design. Ster
Externí odkaz:
https://doaj.org/article/8b9d39eac656462499653dd2c627f9b7
Autor:
Arianna Bonizzi, Marta Truffi, Marta Sevieri, Raffaele Allevi, Leopoldo Sitia, Roberta Ottria, Luca Sorrentino, Cristina Sottani, Sara Negri, Elena Grignani, Serena Mazzucchelli, Fabio Corsi
Publikováno v:
Pharmaceutics, Vol 11, Iss 8, p 384 (2019)
Everolimus (Eve) is an FDA approved drug that inhibits mammalian target of rapamycin (mTOR). It is employed in breast cancer treatment even if its responsiveness is controversial. In an attempt to increase Eve effectiveness, we have developed a novel
Externí odkaz:
https://doaj.org/article/81a228fd099148aa8f27a3c171c325c1
Autor:
Matteo Miceli, Silvana Casati, Roberta Ottria, Simone Di Leo, Ivano Eberini, Luca Palazzolo, Chiara Parravicini, Pierangela Ciuffreda
Publikováno v:
Molecules, Vol 24, Iss 12, p 2241 (2019)
Monoacylglycerol lipase (MAGL) is a serine hydrolase that has a key regulatory role in controlling the levels of 2-arachidonoylglycerol (2-AG), the main signaling molecule in the endocannabinoid system. Identification of selective modulators of MAGL
Externí odkaz:
https://doaj.org/article/d97883d1e57f402bbf4e22f1d6360da5
Autor:
Roberta Ottria, Alessandro Ravelli, Matteo Miceli, Sara Casati, Marica Orioli, Pierangela Ciuffreda
Publikováno v:
Molecules, Vol 24, Iss 9, p 1771 (2019)
The authors wish to make the following corrections to this paper [...]
Externí odkaz:
https://doaj.org/article/73dadb4251624f7dab27dfe3621b9ddd
Autor:
Roberta Ottria, Alessandro Ravelli, Matteo Miceli, Sara Casati, Marica Orioli, Pierangela Ciuffreda
Publikováno v:
Molecules, Vol 24, Iss 5, p 989 (2019)
Olaparib, an orally active inhibitor of poly(ADP-ribose)polymerase(PARP), is the drug of choice in the treatment of gBRCA1/2+ metastatic breast cancers. Unfortunately, Olaparib is poorly soluble with low bioavailability and tumor accumulation; nano-d
Externí odkaz:
https://doaj.org/article/dc3fb5aaf46e4fa5b42d9921ba4f1dcf