Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Roberta Mazzone"'
Autor:
Roberta Mazzone, Clemens Zwergel, Marco Artico, Samanta Taurone, Massimo Ralli, Antonio Greco, Antonello Mai
Publikováno v:
Clinical Epigenetics, Vol 11, Iss 1, Pp 1-15 (2019)
Abstract Epigenetic pathways play a pivotal role in the development and function of the immune system. Over the last decade, a growing body of studies has been published out seeking to explain a correlation between epigenetic modifications and the de
Externí odkaz:
https://doaj.org/article/796fdc3c0e56493099b3451fb7322842
Publikováno v:
Clinical Epigenetics, Vol 9, Iss 1, Pp 1-15 (2017)
Abstract Immune checkpoint factors, such as programmed cell death protein-1/2 (PD-1, PD-2) or cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) receptors, are targets for monoclonal antibodies (MAbs) developed for cancer immunotherapy. Indeed, mod
Externí odkaz:
https://doaj.org/article/66d05d2b20834ef4976f1da2b138f1ed
Autor:
Katia Scotlandi, Antonello Mai, Pier-Luigi Lollini, Patrizia Nanni, Piero Picci, Clara Guerzoni, Michela Pasello, Paola B. Arimondo, Giulia Stazi, Roberta Mazzone, Clemens Zwergel, Lorena Landuzzi, Giordano Nicoletti, Camilla Cristalli, Sergio Valente, Maria Cristina Manara
Additional materials and methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ebb39e856a81e175263a69fe474f9f6
https://doi.org/10.1158/1535-7163.22507170
https://doi.org/10.1158/1535-7163.22507170
Autor:
Katia Scotlandi, Antonello Mai, Pier-Luigi Lollini, Patrizia Nanni, Piero Picci, Clara Guerzoni, Michela Pasello, Paola B. Arimondo, Giulia Stazi, Roberta Mazzone, Clemens Zwergel, Lorena Landuzzi, Giordano Nicoletti, Camilla Cristalli, Sergio Valente, Maria Cristina Manara
Silencing of DNMTs inhibits cell proliferation, induces osteoblastic differentiation and enhances DXR sensitivity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8b1ecaf4a052fd1ac8a72fb5fd582ef
https://doi.org/10.1158/1535-7163.22507176.v1
https://doi.org/10.1158/1535-7163.22507176.v1
Autor:
Katia Scotlandi, Antonello Mai, Pier-Luigi Lollini, Patrizia Nanni, Piero Picci, Clara Guerzoni, Michela Pasello, Paola B. Arimondo, Giulia Stazi, Roberta Mazzone, Clemens Zwergel, Lorena Landuzzi, Giordano Nicoletti, Camilla Cristalli, Sergio Valente, Maria Cristina Manara
Inhibitory activity of MC3343 against human DNMT1 and human DNMT3a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c464b2a0e496cf3a5b5c0cd56da1210
https://doi.org/10.1158/1535-7163.22507167.v1
https://doi.org/10.1158/1535-7163.22507167.v1
Autor:
Katia Scotlandi, Antonello Mai, Pier-Luigi Lollini, Patrizia Nanni, Piero Picci, Clara Guerzoni, Michela Pasello, Paola B. Arimondo, Giulia Stazi, Roberta Mazzone, Clemens Zwergel, Lorena Landuzzi, Giordano Nicoletti, Camilla Cristalli, Sergio Valente, Maria Cristina Manara
The identification of new therapeutic strategies against osteosarcoma, the most common primary bone tumor, continues to be a primary goal to improve the outcomes of patients refractory to conventional chemotherapy. Osteosarcoma originates from the tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c59bc214b1574fdd30f35b4fe19676cd
https://doi.org/10.1158/1535-7163.c.6538608.v1
https://doi.org/10.1158/1535-7163.c.6538608.v1
Autor:
Clemens Zwergel, Michael Schnekenburger, Federica Sarno, Cecilia Battistelli, Maria Cristina Manara, Giulia Stazi, Roberta Mazzone, Rossella Fioravanti, Christina Gros, Frédéric Ausseil, Cristina Florean, Angela Nebbioso, Raffaele Strippoli, Toshikazu Ushijima, Katia Scotlandi, Marco Tripodi, Paola B. Arimondo, Lucia Altucci, Marc Diederich, Antonello Mai, Sergio Valente
Publikováno v:
Clinical Epigenetics. 14
Autor:
Roberta Mazzone, Rossella Fioravanti, Ciro Mercurio, Mario Varasi, Gerald Brosch, Lucia Altucci, Antonello Mai, Mariarosaria Conte, Angela Nebbioso, Sergio Valente, Clemens Zwergel, Elisabetta Di Bello
Starting from the N-hydroxy-3-(4-(2-phenylbutanoyl)amino)phenyl)acrylamide (5 b) previously described by us as a HDAC inhibitor, we prepared four aza-analogues, 6-8, 9 b, as regioisomers containing the pyridine nucleus. Preliminary screening against
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d063c7f21f17821a69c1a32de418cc4
http://hdl.handle.net/11573/1467228
http://hdl.handle.net/11573/1467228
Autor:
Carmela Fimognari, Chiara Marchetti, Eleonora Turrini, Vincenzo Tumiatti, Daniela Tomaselli, Roberta Mazzone, Elena Catanzaro, Anna Minarini, Andrea Milelli
Epigenetic modulators Histone deacetylases (HDACs) and Lysine demethylase (LSD1) are validated targets for anticancer therapy. Both HDAC1/2 and LSD1 are found in association with the repressor protein CoREST in a transcriptional co-repressor complex,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::202dc63b2cc16b93d7b437aecdc96c23
http://hdl.handle.net/11585/630661
http://hdl.handle.net/11585/630661
Publikováno v:
Journal of Management & Governance. 21:599-621
Even though there is clear evidence that large shareholders play an effective monitoring role over poorly-performing CEOs, the monitoring of family owners is yet quite unexplored. This study investigates the impact of family ownership on the CEO turn