Zobrazeno 1 - 10
of 243
pro vyhledávání: '"Roberta Fruttero"'
Publikováno v:
Molecules, Vol 28, Iss 23, p 7870 (2023)
The Guest Editors Federica Sodano, Elena Gazzano, and Roberta Fruttero are pleased to present this editorial overview of the Special Issue entitled “Nitric Oxide Donors for Biomedical Applications: A Themed Issue Dedicated to Professor Alberto Gasc
Externí odkaz:
https://doaj.org/article/8ea6bc8233a54139b76e1408785d3395
Autor:
Loretta Lazzarato, Laura Bianchi, Annapaola Andolfo, Agnese Granata, Matteo Lombardi, Matteo Sinelli, Barbara Rolando, Marina Carini, Alberto Corsini, Roberta Fruttero, Lorenzo Arnaboldi
Publikováno v:
Molecules, Vol 28, Iss 15, p 5724 (2023)
Physiologically, smooth muscle cells (SMC) and nitric oxide (NO) produced by endothelial cells strictly cooperate to maintain vasal homeostasis. In atherosclerosis, where this equilibrium is altered, molecules providing exogenous NO and able to inhib
Externí odkaz:
https://doaj.org/article/5242d759d14f4a8884041774b0f83b09
Publikováno v:
Molecules, Vol 27, Iss 7, p 2337 (2022)
Nitric oxide is a ubiquitous signaling radical that influences critical body functions. Its importance in the cardiovascular system and the innate immune response to bacterial and viral infections has been extensively investigated. The overproduction
Externí odkaz:
https://doaj.org/article/7088fb76771446c4b53dfd4b91b53a88
Autor:
Loretta Lazzarato, Elena Gazzano, Marco Blangetti, Aurore Fraix, Federica Sodano, Giulia Maria Picone, Roberta Fruttero, Alberto Gasco, Chiara Riganti, Salvatore Sortino
Publikováno v:
Antioxidants, Vol 8, Iss 11, p 531 (2019)
The engineering of photosensitizers (PS) for photodynamic therapy (PDT) with nitric oxide (NO) photodonors (NOPD) is broadening the horizons for new and yet to be fully explored unconventional anticancer treatment modalities that are entirely control
Externí odkaz:
https://doaj.org/article/b53bd13b3ff34ae5b83f3aaf040f41a9
Autor:
Iris Chiara Salaroglio, Elena Gazzano, Joanna Kopecka, Konstantin Chegaev, Costanzo Costamagna, Roberta Fruttero, Stefano Guglielmo, Chiara Riganti
Publikováno v:
Molecules, Vol 23, Iss 6, p 1401 (2018)
P-glycoprotein (Pgp) determines resistance to a broad spectrum of drugs used against glioblastoma multiforme (GB). Indeed, Pgp is highly expressed in GB stem cells and in the brain-blood barrier (BBB), the peculiar endothelium surrounding the brain.
Externí odkaz:
https://doaj.org/article/e590f97d13a1430fa187c437db772bb6
Autor:
Elena Reddi, Francesca Spyrakis, Luca Menilli, Salvatore Sortino, Roberta Fruttero, Aurore Fraix, Alberto Gasco, Loretta Lazzarato, Cristina Parisi, Mariacristina Failla, Francesca Moret, Barbara Rolando
Publikováno v:
Chemical Science
The generation of reactive oxygen species (ROS) and reactive nitrogen species (RNS) as “unconventional” therapeutics with precise spatiotemporal control by using light stimuli may open entirely new horizons for innovative therapeutic modalities.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b14864af30e19c642b9289da269058a
https://pubmed.ncbi.nlm.nih.gov/34163730
https://pubmed.ncbi.nlm.nih.gov/34163730
Autor:
Viviana Teresa Orlandi, Stefano Guglielmo, Fabrizio Bolognese, Loretta Lazzarato, Roberta Fruttero, Barbara Rolando
Publikováno v:
Microbiology. 164:1557-1566
Pseudomonas aeruginosa is a microorganism that is well adapted to both clinical and industrial settings, where it can form adherent communities that are difficult to eradicate. New anti-Pseudomonas compounds and strategies are necessary, as the curre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4df1cef61143573c04153e320e4d07f3
https://doi.org/10.1099/mic.0.000730
https://doi.org/10.1099/mic.0.000730
Autor:
Loretta Lazzarato, Alberto Gasco, Elisabetta Marini, Chiara Riganti, Elena Gazzano, Roberta Fruttero, Barbara Rolando, Federica Sodano
Publikováno v:
Bioorganic chemistry. 111
We herein report a study on a set of hybrid compounds in which 3-R-substituted furoxan moieties (R = CH3, CONH2, CN, SO2C6H5), endowed with varying NO-releasing capacities, are joined to a mitochondrial probe, rhodamine B. Each product has been inves
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f93606aeee0f55c06e9228f1e9b5dc6
https://pubmed.ncbi.nlm.nih.gov/33901795
https://pubmed.ncbi.nlm.nih.gov/33901795
Autor:
Roberta Giampietro, Giulia Antonello, Barbara Rolando, Nicola Antonio Colabufo, Stefano Guglielmo, Maria Grazia Perrone, Marialessandra Contino, Chiara Riganti, Roberta Fruttero
Publikováno v:
European journal of medicinal chemistry. 208
In the present study a series of tetrahydroisoquinoline derivatives were synthesized and evaluated for their activity towards three ABC transporters, P-gp, MRP1 and BCRP. The compounds proved to be selective against P-gp. One of them, 8b, displayed a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b8ef4ceeb7ac4d97cd0d0101d661b63
https://pubmed.ncbi.nlm.nih.gov/33007664
https://pubmed.ncbi.nlm.nih.gov/33007664
Publikováno v:
Section 3: Production and Compounding.
Background and importance At the end of 2018 there was a shortage and withdrawal from the market of D-fructose-1,6-diphosphate (Esafosfina), a phosphate source for the extemporaneous preparation of bags for neonatal total parenteral nutrition (TPN).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ebbb58a23a4a79d1ab79bb8bf6f7e640
https://doi.org/10.1136/ejhpharm-2020-eahpconf.48
https://doi.org/10.1136/ejhpharm-2020-eahpconf.48