Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Roberta Franzini"'
Publikováno v:
Symmetry, Vol 13, Iss 6, p 1012 (2021)
Benzodiazepines (BZDs) are an important class of psychoactive drugs with hypnotic-sedative, myorelaxant, anxiolytic and anticonvulsant properties due to interaction with the GABAa receptor in the central nervous system of mammals. BZDs are interestin
Externí odkaz:
https://doaj.org/article/d33e605892ba42f48a697a8a67cd22b1
Autor:
Roberta Franzini, Marco Pierini, Andrea Mazzanti, Antonia Iazzetti, Alessia Ciogli, Claudio Villani
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 1, p 144 (2020)
The presence of stereogenic elements is a common feature in pharmaceutical compounds, and affording optically pure stereoisomers is a frequent issue in drug design. In this context, the study of the chiral molecular recognition mechanism fundamentall
Externí odkaz:
https://doaj.org/article/fb235ed252954b0791923321995d3248
Autor:
Andrea Calcaterra, Laura Mangiardi, Giuliano Delle Monache, Deborah Quaglio, Silvia Balducci, Simone Berardozzi, Antonia Iazzetti, Roberta Franzini, Bruno Botta, Francesca Ghirga
Publikováno v:
Molecules, Vol 25, Iss 2, p 414 (2020)
The Pictet-Spengler reaction (P-S) is one of the most direct, efficient, and variable synthetic method for the construction of privileged pharmacophores such as tetrahydro-isoquinolines (THIQs), tetrahydro-β-carbolines (THBCs), and polyheterocyclic
Externí odkaz:
https://doaj.org/article/d0c1576082484276834c473bc7c1ddab
Autor:
Giulia Mazzoccanti, Roberta Franzini, Alessia Ciogli, Marco Pierini, Cristina Faggi, Antonio Francioso, Claudio Villani
Dibenzocycloctynes have emerged as a promising scaffold for bioorthogonal ligation. An important structural aspect that has not been addressed so far is connected with their chirality. Herein, we explore by theoretical and experimental methods this s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::908f84ad9647a15a4a389ba82c6ea9a0
Autor:
Roberta Franzini, Giulia Marsico, Giovanna LONGHI, Sergio ABBATE, Claudio Villani, Sandra Belviso
Publikováno v:
Dalton transactions (Cambridge, England : 2003). 51(43)
The chiral Ni(II) and Pd(II) complexes of [6]helicene thioethyl porphyrazine have been synthesized and their spectroscopic, electrochemical, and chiroptical properties have been investigated by experimental and computational analyses. In these compou
Autor:
Antonia Iazzetti, Antonio Arcadi, Roberta Franzini, Francesca Ghirga, Giancarlo Fabrizi, Antonella Goggiamani, Andrea Serraiocco, Andrea Fochetti, Federico Marrone
Publikováno v:
European Journal of Organic Chemistry. 2021:1676-1687
Autor:
Roberta Franzini, Valentina Pelliccioli, Claudio Villani, Sergio Abbate, Silvia Cauteruccio, Giuseppe Mazzeo, Emanuela Licandro, Giovanna Longhi
Publikováno v:
New Journal of Chemistry. 45:16442-16451
Conformational chirality is a feature that may arise from the presence of a hindered rotation around a single bond that corresponds to a stereogenic axis. Atropisomers that feature such an element show interesting characteristics suitable for develop
Autor:
Wesley A. Chalifoux, Claudio Villani, Vincent J. Catalano, Giovanna Longhi, Eva Gualtieri, Matteo Tommasini, Ryan Malone, Sergio Abbate, Roberta Franzini, Paban Sitaula, Andrea Lucotti
A mild and efficient synthesis of a broad scope of substituted naphtho[1,2-a]pyrene derivatives was accomplished in good yields using an InCl3/AgNTf2-mediated two-fold alkyne benzannulation reaction. HPLC enantiomeric separation was achieved and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bddaa30e4c78c71c9d5e13f31de46ed
https://hdl.handle.net/11311/1223367
https://hdl.handle.net/11311/1223367
Autor:
Vincent J. Catalano, Sergio Abbate, Roberta Franzini, Matteo Tommasini, Radha Bam, Wesley A. Chalifoux, Claudio Villani, Giovanna Longhi, Marilyn M. Olmstead, Andrea Lucotti, Wenlong Yang
Publikováno v:
Organic Letters. 21:8652-8656
The synthesis of pyreno[a]pyrene-based helicene hybrids was achieved in good yield via a four-fold alkyne benzannulation reaction that was promoted by Bronsted acid. The molecules are configuration...
Autor:
Roberta Franzini, Andrea Renzetti, Claudio Villani, Michele Mancinelli, Emanuela Marotta, Andrea Mazzanti
Publikováno v:
RSC Advances. 9:18165-18175
The assignment of the absolute configuration (AC) of two conformational flexible organic molecules by means of TD-DFT simulation of the electronic circular dichroism (ECD) spectra is presented. The factors leading to a reliable assignment were evalua