Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Roberta Di Fonte"'
Autor:
Simona Serratì, Roberta Di Fonte, Letizia Porcelli, Simona De Summa, Ivana De Risi, Livia Fucci, Eustachio Ruggieri, Tommaso Maria Marvulli, Sabino Strippoli, Rossella Fasano, Tania Rafaschieri, Gabriella Guida, Michele Guida, Amalia Azzariti
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-17 (2023)
Abstract Background Clinical drawback in checkpoint inhibitors immunotherapy (ICI) of metastatic melanoma (MM) is monitoring clinical benefit. Soluble forms of PD1(sPD1) and PD-L1(sPD-L1) and extracellular vesicles (EVs) expressing PD1 and PD-L1 have
Externí odkaz:
https://doaj.org/article/2b5cecf7a196430a882f23e37244ba42
Autor:
Rossella Fasano, Simona Serratì, Tania Rafaschieri, Vito Longo, Roberta Di Fonte, Letizia Porcelli, Amalia Azzariti
Publikováno v:
Biomolecules, Vol 14, Iss 4, p 396 (2024)
Small-cell lung cancer (SCLC) cases represent approximately 15% of all lung cancer cases, remaining a recalcitrant malignancy with poor survival and few treatment options. In the last few years, the addition of immunotherapy to chemotherapy improved
Externí odkaz:
https://doaj.org/article/78f740a08ea9494496023446ce8707c0
Autor:
Roberta Di Fonte, Sabino Strippoli, Marianna Garofoli, Gennaro Cormio, Simona Serratì, Vera Loizzi, Rossella Fasano, Francesca Arezzo, Mariateresa Volpicella, Afshin Derakhshani, Michele Guida, Letizia Porcelli, Amalia Azzariti
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Background: Cervical cancer (CC) is characterized by genomic alterations in DNA repair genes, which could favor treatment with agents causing DNA double-strand breaks (DSBs), such as trabectedin. Hence, we evaluated the capability of trabectedin to i
Externí odkaz:
https://doaj.org/article/74ed80c2cdfa419f867e4d52fcdd7338
Autor:
Katia Danza, Letizia Porcelli, Simona De Summa, Roberta Di Fonte, Brunella Pilato, Rosanna Lacalamita, Simona Serratì, Amalia Azzariti, Stefania Tommasi
Publikováno v:
Molecular Oncology, Vol 16, Iss 4, Pp 904-920 (2022)
Vitamin D is used to reduce cancer risk and improve the outcome of cancer patients, but the vitamin D receptor (VDR; also known as the calcitriol receptor) pathway needs to be functionally intact to ensure the biological effects of circulating calcit
Externí odkaz:
https://doaj.org/article/4a3c78e8a74c4d76a4b251811673088b
Autor:
Simona Serratì, Michele Guida, Roberta Di Fonte, Simona De Summa, Sabino Strippoli, Rosa Maria Iacobazzi, Alessandra Quarta, Ivana De Risi, Gabriella Guida, Angelo Paradiso, Letizia Porcelli, Amalia Azzariti
Publikováno v:
Molecular Cancer, Vol 21, Iss 1, Pp 1-18 (2022)
Abstract Background The immunotherapy with immune checkpoints inhibitors (ICI) has changed the life expectancy in metastatic melanoma (MM) patients. Nevertheless, several patients do not respond hence, the identification and validation of novel bioma
Externí odkaz:
https://doaj.org/article/bb0f7e675ead4af9bb663a4eb45ed84e
Autor:
Michele Guida, Letizia Porcelli, Simona De Summa, Roberta Di Fonte, Ivana De Risi, Marianna Garofoli, Mariapia Caputo, Antonio Negri, Sabino Strippoli, Simona Serratì, Amalia Azzariti
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 5 (2021)
Background Emerging evidence has highlighted the importance of extracellular vesicle (EV)-based biomarkers of resistance to immunotherapy with checkpoint inhibitors in metastatic melanoma. Considering the tumor-promoting implications of urokinase-typ
Externí odkaz:
https://doaj.org/article/3bae0ba1cf6c44589f394797c5e41d5d
Autor:
Letizia Porcelli, Annalisa Mazzotta, Marianna Garofoli, Roberta Di Fonte, Gabriella Guida, Michele Guida, Stefania Tommasi, Amalia Azzariti
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 133, Iss , Pp 111006- (2021)
The crosstalk between Notch and MAPK pathway plays a role in MEK inhibitor resistance in BRAFV600E metastatic melanoma (MM) and promotes migration in GNAQQ209L uveal melanoma (UM) cells. We determined the cytotoxicity of combinatorial inhibition of M
Externí odkaz:
https://doaj.org/article/6ac1569cd0094719bfacf8d744774d0e
Autor:
Annamaria Pratelli, Maria Stella Lucente, Marco Cordisco, Stefano Ciccarelli, Roberta Di Fonte, Alessio Sposato, Viviana Mari, Paolo Capozza, Francesco Pellegrini, Grazia Carelli, Amalia Azzariti, Canio Buonavoglia
Publikováno v:
Animals, Vol 11, Iss 12, p 3350 (2021)
The evolution of a bovine coronavirus (BCoV) natural infection in a calf persistently infected with bovine viral diarrhea virus (BVDV) was described. The infected calf developed intermittent nasal discharge, diarrhea and hyperthermia. The total numbe
Externí odkaz:
https://doaj.org/article/475a6e28a8fb4acfa561315b68492c9b
Autor:
Stefania Tommasi, Letizia Porcelli, Roberta Di Fonte, Simona De Summa, Rosanna Lacalamita, Amalia Azzariti, Brunella Pilato, Katia Danza, Simona Serratì
Publikováno v:
Molecular Oncology, Vol 16, Iss 4, Pp 904-920 (2022)
Vitamin D is used to reduce cancer risk and improve the outcome of cancer patients, but the vitamin D receptor (VDR; also known as the calcitriol receptor) pathway needs to be functionally intact to ensure the biological effects of circulating calcit
Autor:
Rosa Maria Iacobazzi, Ilaria Arduino, Roberta Di Fonte, Angela Assunta Lopedota, Simona Serratì, Giuseppe Racaniello, Viviana Bruno, Valentino Laquintana, Byung-Chul Lee, Nicola Silvestris, Francesco Leonetti, Nunzio Denora, Letizia Porcelli, Amalia Azzariti
Publikováno v:
Cancers, Vol 14, Iss 5, p 5 (2022)
Cancers; Volume 14; Issue 1; Pages: 5
Cancers
Cancers; Volume 14; Issue 1; Pages: 5
Cancers
Simple Summary This research suggests a new potential therapeutic approach to pancreatic ductal adenocarcinoma to improve drug effectiveness and overcome drug resistance. A double actively targeted gemcitabine delivery system, consisting of polymeric