Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Roberta Depenni"'
Autor:
Chiara Chiavelli, Malvina Prapa, Giulia Rovesti, Marco Silingardi, Giovanni Neri, Giuseppe Pugliese, Lucia Trudu, Massimiliano Dall’Ora, Giulia Golinelli, Giulia Grisendi, Jonathan Vinet, Marco Bestagno, Carlotta Spano, Roberto Vito Papapietro, Roberta Depenni, Katia Di Emidio, Anna Pasetto, Daniela Nascimento Silva, Alberto Feletti, Silvia Berlucchi, Corrado Iaccarino, Giacomo Pavesi, Massimo Dominici
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-9 (2024)
Abstract Glioblastoma (GBM) remains a deadly tumor. Treatment with chemo-radiotherapy and corticosteroids is known to impair the functionality of lymphocytes, potentially compromising the development of autologous CAR T cell therapies. We here genera
Externí odkaz:
https://doaj.org/article/b35ac19b1e9c4db4933d30af0c9b01a2
Autor:
Christophe Le Tourneau, Massimo Ghiani, Maria Chiara Cau, Roberta Depenni, Graziana Ronzino, Pierluigi Bonomo, Vincenzo Montesarchio, Luigi Leo, Jeltje Schulten, Satu Salmio, Diethelm Messinger, Andrea Sbrana, Edith Borcoman, Maria Grazia Ghi
Publikováno v:
Cancer Reports, Vol 6, Iss 5, Pp n/a-n/a (2023)
Abstract Background ENCORE, an observational, prospective, open‐label study, investigated real‐world treatment practices and outcomes with cetuximab plus platinum‐based therapy (PBT) in first‐line (1L) recurrent and/or metastatic squamous cel
Externí odkaz:
https://doaj.org/article/2aac3541984b4cb79407e47c1b6ba1ae
Autor:
Malvina Prapa, Chiara Chiavelli, Giulia Golinelli, Giulia Grisendi, Marco Bestagno, Rosanna Di Tinco, Massimiliano Dall’Ora, Giovanni Neri, Olivia Candini, Carlotta Spano, Tiziana Petrachi, Laura Bertoni, Gianluca Carnevale, Giuseppe Pugliese, Roberta Depenni, Alberto Feletti, Corrado Iaccarino, Giacomo Pavesi, Massimo Dominici
Publikováno v:
npj Precision Oncology, Vol 5, Iss 1, Pp 1-14 (2021)
Abstract Glioblastoma is the most malignant primary brain tumor and is still in need of effective medical treatment. We isolated patient-derived glioblastoma cells showing high GD2 antigen expression representing a potential target for CAR T strategy
Externí odkaz:
https://doaj.org/article/adec4e412bad4650b333a7a1399b723b
Autor:
Sara De Biasi, Lara Gibellini, Domenico Lo Tartaro, Simone Puccio, Claudio Rabacchi, Emilia M. C. Mazza, Jolanda Brummelman, Brandon Williams, Kelly Kaihara, Mattia Forcato, Silvio Bicciato, Marcello Pinti, Roberta Depenni, Roberto Sabbatini, Caterina Longo, Massimo Dominici, Giovanni Pellacani, Enrico Lugli, Andrea Cossarizza
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Immune checkpoint inhibition (ICI) shows potential for cancer therapies, but response rates vary. Here, the authors use single-cell analyses to show that, in a 28 patient cohort, patients stratified by mucosal-associated invariant T (MAIT) percentage
Externí odkaz:
https://doaj.org/article/5dde8cd7955f4749b3113f29084ac913
Autor:
Giovanni Grignani, Vanna Chiarion Sileni, Carmine Pinto, Roberta Depenni, Nicola Fazio, Luca Galli, Dario Giuffrida, Carlo Carnaghi, Domenico Ciliberto, Domenico C. Corsi, Paola Queirolo, Elena Benincasa, Filippo Venturini, Gennaro Fazzi, Nuno Costa, Paolo Antonio Ascierto
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-11 (2021)
Abstract Background The incidence of Merkel cell carcinoma (MCC), a rare form of skin cancer with a poor prognosis, has increased in Italy in recent decades. Avelumab, an anti-programmed death ligand 1 monoclonal antibody, is approved for the treatme
Externí odkaz:
https://doaj.org/article/f52e875346f74ef69cff61e898b81684
Autor:
Lara Gibellini, Sara De Biasi, Camillo Porta, Domenico Lo Tartaro, Roberta Depenni, Giovanni Pellacani, Roberto Sabbatini, Andrea Cossarizza
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Novel treatments based upon the use of immune checkpoint inhibitors have an impressive efficacy in different types of cancer. Unfortunately, most patients do not derive benefit or lasting responses, and the reasons for the lack of therapeutic success
Externí odkaz:
https://doaj.org/article/da0c71756ae047a2bd4ae92aab0c6dd8
Autor:
Francesco Mattioli, Alfredo Lo Manto, Matteo Miglio, Edoardo Serafini, Davide Rossi, Sara Valerini, Roberto Tonelli, Matteo Fermi, Giuseppe Pugliese, Federica Bertolini, Elisa D'Angelo, Roberta Depenni, Massimo Dominici, Frank R. H. Lohr, Daniele Marchioni
Publikováno v:
Head and Neck. John Wiley and Sons Inc.
Background: Distant metastasis (DM) development in Oropharyngeal Squamous Cell Carcinoma (OPSCC) represents an important prognostic factor. The identification of a phenotype of metastatic patients may better define therapeutic and follow-up programs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6dd89b495b410ab232c3a32917597bf
https://doi.org/10.1002/hed.27354
https://doi.org/10.1002/hed.27354
Autor:
Christophe Le Tourneau, Massimo Ghiani, Maria Chiara Cau, Roberta Depenni, Graziana Ronzino, Pierluigi Bonomo, Vincenzo Montesarchio, Luigi Leo, Jeltje Schulten, Satu Salmio, Diethelm Messinger, Andrea Sbrana, Edith Borcoman, Maria Grazia Ghi
Publikováno v:
Cancer Reports. 6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3aac4d79949cef5cbd38602287c3927
https://doi.org/10.1002/cnr2.1804
https://doi.org/10.1002/cnr2.1804
Autor:
Sara De Biasi, Annalisa Guida, Domenico Lo Tartaro, Martina Fanelli, Roberta Depenni, Massimo Dominici, Greg Finak, Camillo Porta, Annamaria Paolini, Rebecca Borella, Carlo Bertoldi, Andrea Cossarizza, Roberto Sabbatini, Lara Gibellini
Publikováno v:
Cytometry Part A. 101:597-605
Renal-cell carcinoma (RCC) is responsible for the majority of tumors arising from the kidney parenchyma. Although a progressive improvement in median overall survival has been observed after the introduction of anti-PD-1 therapy, many patients do not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73cd4273e4d6708a90c46885b6f364a0
https://doi.org/10.1002/cyto.a.24562
https://doi.org/10.1002/cyto.a.24562
Autor:
Massimo Dominici, Cinzia Baldessari, Giuseppe Pugliese, Stefano Greco, Fabio Canino, Roberta Depenni
Publikováno v:
Tumori Journal. 107:NP123-NP126
Immune-related myasthenia gravis is a rare, disabling, and potentially fatal adverse event of immune checkpoint inhibitor treatment. It is important to identify and manage it promptly. We present two cases of immune-related de novo myasthenia gravis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6ca74c2f473043a12d52b15a9639487
https://doi.org/10.1177/03008916211040559
https://doi.org/10.1177/03008916211040559