Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Roberta D. Shahin"'
Publikováno v:
The Journal of Experimental Medicine
To investigate the fundamental nature of protective immunity to Bordetella pertussis, we studied intranasal immunization of adult mice with formalin-fixed B. pertussis (FFBP), followed by aerosol B. pertussis challenge. Mice given two doses of FFBP i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08e087c345a78c4edf92b1be3b3094fe
https://doi.org/10.1084/jem.191.11.1841
https://doi.org/10.1084/jem.191.11.1841
Contribution of Regulation by the bvg Locus to Respiratory Infection of Mice by Bordetella pertussis
Publikováno v:
Infection and Immunity. 66:4367-4373
Whooping cough is an acute respiratory disease caused by the small, gram-negative bacterium Bordetella pertussis. B. pertussis expresses several factors that contribute to its ability to cause disease. These factors include surface-associated molecul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faebc510e5647b59be7288c5c88eb0a8
https://doi.org/10.1128/iai.66.9.4367-4373.1998
https://doi.org/10.1128/iai.66.9.4367-4373.1998
Publikováno v:
Infection and Immunity. 60:1482-1488
Mucosal immunization ofmicewithpurified BordeteUla pertussis filamentous hemagglutinin (FHA), byeither therespiratory orthegutroute, was foundtoprotect against B.pertussis infection ofthetrachea andlungs. Intranasal immunization ofBALB/cand(C57BL/6 x
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26f9ffa443e10aae337a363e46bf60c2
https://doi.org/10.1128/iai.60.4.1482-1488.1992
https://doi.org/10.1128/iai.60.4.1482-1488.1992
Publikováno v:
The Journal of Experimental Medicine
Immunization with the 69-kD outer membrane protein (OMP) of Bordetella pertussis protected neonatal mice against lethal respiratory challenge with B. pertussis 18323. Active immunization elicited a serum IgG anti-69-kD OMP response at the time of cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14ea35b6307c955e48cdeb42c4f8998a
https://doi.org/10.1084/jem.171.1.63
https://doi.org/10.1084/jem.171.1.63
Publikováno v:
Infection and immunity. 65(12)
Using a mouse model of Bordetella pertussis infection, we have analyzed the role of gamma interferon (IFN-gamma) in bacterial clearance from the respiratory tract. Adult BALB/c mice began to clear a respiratory infection within 3 weeks postinfection,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a26b2a1e8edb61f8c63507441c5f3d76
https://pubmed.ncbi.nlm.nih.gov/9393774
https://pubmed.ncbi.nlm.nih.gov/9393774
Autor:
Roberta D. Shahin, Michael J. Brennan
Publikováno v:
American journal of respiratory and critical care medicine. 154(4 Pt 2)
Infectious disease processes follow the initial steps of adherence of the organism to host tissues and subsequent colonization of the target tissues that can occur through specific adhesion-receptor systems. Bordetella pertussis, the human pathogen t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ee1c0e3a227a9893f4f2f7b0adabca2
https://pubmed.ncbi.nlm.nih.gov/8876533
https://pubmed.ncbi.nlm.nih.gov/8876533
Publikováno v:
Infection and immunity. 61(4)
Systemic and mucosal B-cell-mediated immune responses to purified filamentous hemagglutinin (FHA) in mice were analyzed at different times following a single respiratory infection with Bordetella pertussis. Serum immunoglobulin G (IgG) anti-FHA and r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d27205ba66bb192daaf7955ed5eefa71
https://pubmed.ncbi.nlm.nih.gov/8454349
https://pubmed.ncbi.nlm.nih.gov/8454349
Publikováno v:
Springer seminars in immunopathology. 15(2-3)
In summary, the LOS of B. pertussis lacks the long-chain polysaccharide O antigen, and is resolved electrophoretically into two distinct bands designated LOS A and LOS B. Mice administered with anti-LOS A mAbs can be protected from fatal B. pertussis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29cd24c3da3e26d374666917019a805a
https://pubmed.ncbi.nlm.nih.gov/8256198
https://pubmed.ncbi.nlm.nih.gov/8256198
Autor:
Roberta D. Shahin, Charles R. Manclark, Michael J. Brennan, Bruce D. Meade, Drusilla L. Burns
Publisher Summary This chapter describes Bordetella pertussis and discusses recent advances in the development of pertussis vaccines. Bordetella pertussis is the pathogen that causes the human respiratory disease known as whooping cough, or pertussis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf808bcc8c6f4ac5e575fcde326e800c
https://doi.org/10.1016/b978-0-7506-9265-6.50008-7
https://doi.org/10.1016/b978-0-7506-9265-6.50008-7
Autor:
J L Arciniega, T D Bartley, W N Burnette, D W Whiteley, Drusilla L. Burns, Roberta D. Shahin, V L Mar
Publikováno v:
Infection and immunity. 59(10)
An enzymatically deficient recombinant S1 subunit, in which Arg-9 was replaced by Lys, was combined with native B oligomer to form a mutant holotoxin molecule. This molecule exhibited decreased leukocytosis-promoting and histamine-sensitizing activit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a3eadd9fbaa9d10099611217b22508d
https://pubmed.ncbi.nlm.nih.gov/1894354
https://pubmed.ncbi.nlm.nih.gov/1894354