Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Roberta Bongiorno"'
Autor:
Roberta Bongiorno, Mara Lecchi, Laura Botti, Oriana Bosco, Chiara Ratti, Enrico Fontanella, Nicolò Mercurio, Pietro Pratesi, Claudia Chiodoni, Paolo Verderio, Mario Paolo Colombo, Daniele Lecis
Publikováno v:
Cell Death and Disease, Vol 15, Iss 9, Pp 1-13 (2024)
Abstract Breast cancer is the most frequent type of tumor in women and is characterized by variable outcomes due to its heterogeneity and the presence of many cancer cell-autonomous and –non-autonomous factors. A major determinant of breast cancer
Externí odkaz:
https://doaj.org/article/a7a58a8a61674d479f632a6243ee52f0
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-11 (2021)
Abstract Nonsense-mediated mRNA decay (NMD) is a highly conserved cellular surveillance mechanism, commonly studied for its role in mRNA quality control because of its capacity of degrading mutated mRNAs that would produce truncated proteins. However
Externí odkaz:
https://doaj.org/article/99e0e643f82840e9937f59e512b30aa1
Nonsense mutations affect 10% of patients with cystic fibrosis and produce a premature termination codon in CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) mRNA causing early termination of translation and leading to lack of CFTR function.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3658::d853cf68f08bef79b596d6387112edfe
http://hdl.handle.net/10447/510797
http://hdl.handle.net/10447/510797
