Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Roberta A. Parente"'
Publikováno v:
Biochemistry. 33:6721-6731
A kinetic model for pore-mediated and perturbation-mediated flip-flop is presented and used to characterize the mechanism of peptide-induced phospholipid flip-flop in bilayers. The model assumes that certain peptides can bind to and aggregate within
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::797f1f86a30664179d6658fd6512e8a1
https://doi.org/10.1021/bi00187a044
https://doi.org/10.1021/bi00187a044
Publikováno v:
Biochemistry. 29:8713-8719
The solution properties and bilayer association of two synthetic 30 amino acid peptides, GALA and LAGA, have been investigated at pH 5 and 7.5. These peptides have the same amino acid composition and differ only in the positioning of glutamic acid an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42405a8fd0edc1fbf3ca0b403dc88ef3
https://doi.org/10.1021/bi00489a030
https://doi.org/10.1021/bi00489a030
Publikováno v:
Biochemistry. 29:8720-8728
The synthetic, amphipathic peptide GALA undergoes a pH-dependent conformational change and induces leakage of contents from large unilamellar phosphatidylcholine vesicles when in a helical conformation. The kinetics of this process have been investig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f7930c7af9200c416e85f0a75d8a677
https://doi.org/10.1021/bi00489a031
https://doi.org/10.1021/bi00489a031
Autor:
Theodore F. Taraschi, Sol M. Gruner, Andrew S. Janoff, Keir C. Neuman, Sharma R. Minchey, Walter Perkins, Richard B. Dause, Roberta A. Parente
Publikováno v:
Science. 273:330-332
The development of artificial surfactants for the treatment of respiratory distress syndrome (RDS) requires lipid systems that can spread rapidly from solution to the air-water interface. Because hydration-repulsion forces stabilize liposomal bilayer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f643c8eafe384e64a12d5c2c87c5768
https://doi.org/10.1126/science.273.5273.330
https://doi.org/10.1126/science.273.5273.330
Autor:
Elias Fattal, Jan Wilschut, Shlomo Nir, Roberta A. Parente, Francis C. SzokaJr., Jose L. Nieva
Publikováno v:
Trafficking of Intracellular Membranes: ISBN: 9783642795497
The understanding of the interrelationships among dynamics, structure, and function of membrane-interacting peptide segments has been intensely studied during the last decade.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f44745ab067c25d2928a603b5875b08
https://doi.org/10.1007/978-3-642-79547-3_6
https://doi.org/10.1007/978-3-642-79547-3_6
Autor:
Joëlle De Meutter, Erik Goormaghtigh, Francis C. Szoka, Roberta A. Parente, Véronique Cabiaux, Jean Marie Ruysschaert
Publikováno v:
European journal of biochemistry. 195(2)
GALA, a synthetic, amphipathic 30-amino-acid peptide, based upon a Glu-Ala-Leu-Ala motive, was designed to mimic the behavior of viral fusion proteins. GALA is a water-soluble peptide with an aperiodic conformation at neutral pH, and becomes an amphi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0d54e678f70aff2115c6ddcf17d9ce2
https://pubmed.ncbi.nlm.nih.gov/1997324
https://pubmed.ncbi.nlm.nih.gov/1997324
Autor:
Roberta A. Parente, Barry R. Lentz
Publikováno v:
Biochemistry. 23:2353-2362
Large unilamellar vesicles (LUV) have been prepared by three procedures from several synthetic and natural phosphatidylcholines. Reverse-phase evaporation vesicles (REV) and fusion vesicles were prepared by established procedures. A published procedu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a243ae50e278ac17e02ad798ec955eb
https://doi.org/10.1021/bi00306a005
https://doi.org/10.1021/bi00306a005
Publikováno v:
Journal of Biological Chemistry. 263:4724-4730
A synthetic, amphipathic 30-amino acid peptide with the major repeat unit Glu-Ala-Leu-Ala (GALA) was designed to mimic the behavior of the fusogenic sequences of viral fusion proteins. GALA is a water-soluble peptide with an aperiodic conformation at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5de83a62fbad4bbbba148051964ca93
https://doi.org/10.1016/s0021-9258(18)68843-x
https://doi.org/10.1016/s0021-9258(18)68843-x
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 812:493-502
Differential scanning calorimetry and freeze-fracture electron microscopy have been used to characterize the phase behavior and morphology of two types of unilamellar vesicles composed of synthetic phosphatidylcholines. The first type displayed an av
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10606b479945a1a3482d46cdad4a83dc
https://doi.org/10.1016/0005-2736(85)90324-4
https://doi.org/10.1016/0005-2736(85)90324-4
Publikováno v:
Biochemistry. 26:2964-2972
A 30-residue amphipathic peptide was designed to interact with uncharged bilayers in a pH-dependent fashion. This was achieved by a pH-induced random coil-alpha-helical transition, exposing a hydrophobic face in the peptide. The repeat unit of the pe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52e96e83bfba5091ae21fc3443af34d1
https://doi.org/10.1021/bi00385a002
https://doi.org/10.1021/bi00385a002