Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Roberta A. Gillespie"'
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e32263 (2012)
Alcohol consumption during adolescence has long-term sexually dimorphic effects on anxiety behavior and mood disorders. We have previously shown that repeated binge-pattern alcohol exposure increased the expression of two critical central regulators
Externí odkaz:
https://doaj.org/article/c599aed2153b469aab15a377e155f397
Autor:
Magdalena M Przybycien-Szymanska, Natasha N Mott, Caitlin R Paul, Roberta A Gillespie, Toni R Pak
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18350 (2011)
Adolescence is a dynamic and important period of brain development however, little is known about the long-term neurobiological consequences of alcohol consumption during puberty. Our previous studies showed that binge-pattern ethanol (EtOH) treatmen
Externí odkaz:
https://doaj.org/article/1f005883ac9c49b5a2bec370a4cd7de1
Publikováno v:
Brain Research. 1383:13-21
This laboratory showed that ethanol augments apoptosis in fetal rhombencephalic neurons and co-treatment with alpha-lipoic acid (LA) or one of several other antioxidants prevents ethanol-associated apoptosis. Because ethanol increases oxidative stres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80e886eb3b694a741292a61bff0d5e56
https://doi.org/10.1016/j.brainres.2011.01.113
https://doi.org/10.1016/j.brainres.2011.01.113
Publikováno v:
Developmental Brain Research. 121:133-143
This laboratory previously showed that in utero ethanol exposure severely impairs the development of the cell bodies and projections of serotonin (5-HT) neurons, and that maternal treatment with a 5-HT(1A) agonist prevents many of these abnormalities
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f75e3c76d0940a18dd21178e50e39262
https://doi.org/10.1016/s0165-3806(00)00029-8
https://doi.org/10.1016/s0165-3806(00)00029-8
Publikováno v:
Alcoholism: Clinical and Experimental Research. 21:1169-1178
In utero ethanol exposure results in a decreased concentration of serotonin (5-HT) in brain regions containing the cell bodies of 5-HT neurons and their cortical projections. The concentration of 5-HT reuptake sites is also reduced in several brain a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::26f81adbdc249612bc3918fbcba5d4de
https://doi.org/10.1111/j.1530-0277.1997.tb04434.x
https://doi.org/10.1111/j.1530-0277.1997.tb04434.x
Publikováno v:
Alcoholism: Clinical and Experimental Research. 21:452-459
Previously, it was shown that in utero ethanol exposure results in decreased serotonin (5-HT) and altered concentrations of 5-HT reuptake sites and 5-HT 1A receptors in fetal and/or postnatal rats. Because fetal 5-HT is an essential trophic factor, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8606fda3157f5faca1599119787d776
https://doi.org/10.1111/j.1530-0277.1997.tb03790.x
https://doi.org/10.1111/j.1530-0277.1997.tb03790.x
Publikováno v:
Alcoholism: Clinical and Experimental Research. 18:47-52
Previous work in this and other laboratories has demonstrated that in utero ethanol exposure adversely affects the development of the serotonergic, dopaminergic, cholinergic, and other neurotransmitter systems. In several of these systems, receptor n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44dbbea49d224b30246853028caff3a6
https://doi.org/10.1111/j.1530-0277.1994.tb00879.x
https://doi.org/10.1111/j.1530-0277.1994.tb00879.x
Publikováno v:
Brain research. 1150
Previously, this laboratory demonstrated that ethanol treatment significantly reduces the number of developing serotonin (5-HT) and other fetal rhombencephalic neurons in rats by augmenting apoptosis. Using a 5-HT 1A agonist we were able to attenuate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc2cf82fc9e02c985293fb9fd6167585
https://pubmed.ncbi.nlm.nih.gov/17400198
https://pubmed.ncbi.nlm.nih.gov/17400198
Publikováno v:
Brain research. 1092(1)
Previously, this laboratory demonstrated that ethanol reduces the number of developing serotonin (5-HT)-containing neurons by increasing apoptosis. We also found that 5-HT(1A) agonists attenuate the proapoptotic effects of ethanol and the ethanol-med
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01765f89d4ed7e6471ce7b29de54a949
https://pubmed.ncbi.nlm.nih.gov/16687129
https://pubmed.ncbi.nlm.nih.gov/16687129
Publikováno v:
Brain research. Developmental brain research. 159(1)
Previously, this laboratory demonstrated that developing serotonin (5-HT) neurons and other fetal rhombencephalic neurons are reduced by in vivo and in vitro exposure to ethanol, effects that are related to ethanol's augmentation of apoptosis. We als
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e17af66248628df6ea4239fd6e54cd7a
https://pubmed.ncbi.nlm.nih.gov/16081165
https://pubmed.ncbi.nlm.nih.gov/16081165