Zobrazeno 1 - 10
of 94
pro vyhledávání: '"Roberta A Jorgensen"'
Autor:
Andrea A. Gossard, Alisha C. Stahler, Marina G. Silveira, Keith D. Lindor, Janice L. Petz, Ahmad H. Ali, Roberta A. Jorgensen
Publikováno v:
American Journal of Therapeutics. 24:e167-e176
Background and aims Fatigue is a common symptom of primary biliary cirrhosis (PBC), and is associated with an impaired quality of life. Study question No studies have assessed the use of modafinil in fatigue related to PBC in a controlled manner. Stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::225959d2c47ea3cdf031043fffe8edd6
https://doi.org/10.1097/mjt.0000000000000387
https://doi.org/10.1097/mjt.0000000000000387
Autor:
James H. Tabibian, John E. Eaton, Andrea A. Gossard, Anilga Tabibian, Jan Petz, Keith D. Lindor, Mounif El-Youssef, Felicity B. Enders, Roberta A. Jorgensen
Publikováno v:
American Journal of Therapeutics. 24:e56-e63
Primary sclerosing cholangitis (PSC) is a rare, chronic, cholestatic liver disease in which emerging data suggest that oral antibiotics may offer therapeutic effects. We enrolled patients with PSC in a 12-week, open-label pilot study to investigate t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4867ad0d8f654ad1a49805d6fe6788ae
https://doi.org/10.1097/mjt.0000000000000102
https://doi.org/10.1097/mjt.0000000000000102
Autor:
Keith D. Lindor, Evangelos Kalaitzakis, Matthias Neuhauser, Roberta A. Jorgensen, Einar Björnsson, Jayant A. Talwalkar, Roger W. Chapman, Felicity Enders, Hardy Maetzel
Background: Fatigue was recently suggested to predict an increased risk of mortality in a primary biliary cirrhosis (PBC) cohort during follow-up. Aims: To analyse the impact of fatigue on prognosis in PBC. Methods: Patients with PBC who had earlier
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::498f8387dcd261c791f236f7a46d9221
https://doi.org/10.1111/j.1478-3231.2009.02160.x
https://doi.org/10.1111/j.1478-3231.2009.02160.x
Publikováno v:
Digestive and Liver Disease. 44:44-48
Background Limited data are available regarding the serum lipids in primary sclerosing cholangitis. Aims To determine the lipid levels in patients with primary sclerosing cholangitis. Methods We monitored the serum lipid levels annually for up to 6 y
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99ca49b5a5a69fedf6849af479ecbd48
https://doi.org/10.1016/j.dld.2011.07.020
https://doi.org/10.1016/j.dld.2011.07.020
Publikováno v:
Liver International. 32:790-795
Background Biochemical tests have been recommended as endpoints for clinical trials in primary biliary cirrhosis (PBC) because the use of liver transplantation and death as endpoints in ursodeoxycholic acid (UDCA) therapeutic trials is unfeasible. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1b8880f82625a5b33a234f110daf012
https://doi.org/10.1111/j.1478-3231.2011.02678.x
https://doi.org/10.1111/j.1478-3231.2011.02678.x
Autor:
Keith D. Lindor, Kris V. Kowdley, Andrea A. Gossard, Denise M. Harnois, Jill C. Keach, Emmanouil Sinakos, Mohamad Imam, Alisha C. DeCook, Timothy M. McCashland, M. Edwyn Harrison, Velimir A. Luketic, Jan Petz, Roberta A. Jorgensen, Felicity Enders, Alex S. Befeler
Publikováno v:
Alimentary Pharmacology & Therapeutics. 34:1185-1192
Aliment Pharmacol Ther 2011; 34: 1185–1192 Summary Background Ursodeoxycholic acid (UDCA) in a dose of 28–30 mg/kg/day increases the likelihood of clinical deterioration of primary sclerosing cholangitis (PSC) patients. Aim To compare the risk of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d93168440f55042d88b7eb6f1758635a
https://doi.org/10.1111/j.1365-2036.2011.04863.x
https://doi.org/10.1111/j.1365-2036.2011.04863.x
Autor:
Emmanouil Sinakos, M. Edwyn Harrison, Timothy M. McCashland, Kris V. Kowdley, Marina G. Silveira, Darrell S. Pardi, Jan Petz, Velimir A. Luketic, John E. Eaton, Alex S. Befeler, Keith D. Lindor, Roberta A. Jorgensen, Denise M. Harnois
Publikováno v:
American Journal of Gastroenterology. 106:1638-1645
Some studies have suggested that ursodeoxycholic acid (UDCA) may have a chemopreventive effect on the development of colorectal neoplasia in patients with ulcerative colitis (UC) and primary sclerosing cholangitis (PSC). We examined the effects of hi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38382e0c7b6d7a0c5aee82843d7d672a
https://doi.org/10.1038/ajg.2011.156
https://doi.org/10.1038/ajg.2011.156
Autor:
Paul Angulo, Ayako Suzuki, Jill C. Keach, Michael Charlton, James F. Lymp, Jan Petz, Keith D. Lindor, Roberta A. Jorgensen
Publikováno v:
Food and Nutrition Sciences. :67-73
Background: Mitochondrial dysfunction plays a pivotal role in the progression of nonalcoholic steatohepatitis (NASH). L-alanine was shown to restore ATP content and protect the liver in various liver injury models. Aim: To assess the safety and thera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38a6f7823ef45a573f54c9d5a10d10b9
https://doi.org/10.4236/fns.2010.12011
https://doi.org/10.4236/fns.2010.12011
Autor:
Keith D. Lindor, Janice L. Petz, Jayant A. Talwalkar, Roberta A. Jorgensen, Phunchai Charatcharoenwitthaya, Andrea A. Gossard, Jill C. Keach, Paul Angulo
Publikováno v:
Digestive Diseases and Sciences. 55:476-483
Blockade of angiotensin II synthesis attenuates hepatic fibrosis in different experimental models of chronic liver injury. We evaluated the safety and efficacy of moexipril, an angiotensin-converting enzyme inhibitor, in patients with primary biliary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7010bbc4f5985b53b3137acba8f5f60
https://doi.org/10.1007/s10620-009-0744-1
https://doi.org/10.1007/s10620-009-0744-1
Autor:
Marina G. Silveira, RN Janice L Petz, Keith D. Lindor, Natalie J. Török, Roberta A. Jorgensen, Jill C. Keach, Andrea A. Gossard
Publikováno v:
The American Journal of Gastroenterology. 104:83-88
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease of young adults that is associated with significant morbidity and mortality. No effective medical therapy is available. Minocycline has been found to exert biological effects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6591c05cf68304a581c5dffefedb0132
https://doi.org/10.1038/ajg.2008.14
https://doi.org/10.1038/ajg.2008.14