Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Roberta Glynn"'
Autor:
Roberta Glynn, Steven Mathieu, David Bauer, Jeevanandam Arumugasamy, Jie Li, Jingyang Wang, Alistair Stewart, Alan Becker, Jinsoo Lim, Elodie Rosinovsky, F. Patrick McGarry, Narayan Chaudhuri, G. Mark Latham, Erkan Baloglu, Adrien F. Soret, Kannan Arunachalam, Jia Liu, Adel Moussa, Benjamin Alexander Mayes
Publikováno v:
Organic Process Research & Development. 19:520-530
A scalable process is described for the synthesis of 2′-C-methylguanosine-5′-[2-[(3-hydroxy-2,2-dimethyl-1-oxopropyl)thio]ethyl-N-benzylphosphoramidate], a nucleotide prodrug inhibitor of hepatitis C virus NS5B polymerase. The route features the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59db1becbb4e9c2c9f190d64e71e6d6b
https://doi.org/10.1021/op5003837
https://doi.org/10.1021/op5003837
Autor:
Xinghua Wu, Jia Liu, Catherine Caillet, Aurelien E. Salanson, Kannan Arunachalam, David Bauer, Jeevanandam Arumugasamy, Elodie Rosinovsky, Jingyang Wang, G. Mark Latham, Benjamin Alexander Mayes, Roberta Glynn, Alistair Stewart, Jinsoo Lim, Alan Becker, Adrien F. Soret, Adel Moussa
Publikováno v:
Organic Process Research & Development. 17:811-828
A novel assembly of two structurally related 14-membered ring macrocyclic hepatitis C virus protease inhibitors is presented. Key to their successful construction was an ultimate ring-closing metathesis step on the respective highly functionalized di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::031e1232dac381e175cc5e16fece6b3b
https://doi.org/10.1021/op300296t
https://doi.org/10.1021/op300296t
Autor:
Benjamin A. Mayes, Jingyang Wang, Jeevanandam Arumugasamy, Kannan Arunachalam, Erkan Baloglu, David Bauer, Alan Becker, Narayan Chaudhuri, Roberta Glynn, G. Mark Latham, Jie Li, Jinsoo Lim, Jia Liu, Steve Mathieu, F. Patrick McGarry, Elodie Rosinovsky, Adrien F. Soret, Alistair Stewart, Adel Moussa
Publikováno v:
Organic Process Research & Development; Apr2015, Vol. 19 Issue 4, p520-530, 11p