Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Roberta, Torregrossa"'
Autor:
Katarzyna Magierowska, Dagmara Wójcik-Grzybek, Edyta Korbut, Dominik Bakalarz, Grzegorz Ginter, Aleksandra Danielak, Sławomir Kwiecień, Anna Chmura, Roberta Torregrossa, Matthew Whiteman, Marcin Magierowski
Publikováno v:
Redox Biology, Vol 66, Iss , Pp 102847- (2023)
Hydrogen sulfide (H2S) signaling and H2S-prodrugs maintain redox balance in gastrointestinal (GI) tract. Predominant effect of any H2S-donor is mitochondrial. Non-targeted H2S-moieties were shown to decrease the non-steroidal anti-inflammatory drugs
Externí odkaz:
https://doaj.org/article/2024b98d268e470aa189cebc2ff9854c
Autor:
Rebecca A. Ellwood, Luke Slade, Jonathan Lewis, Roberta Torregrossa, Surabhi Sudevan, Mathew Piasecki, Matthew Whiteman, Timothy Etheridge, Nathaniel J. Szewczyk
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-12 (2022)
A C. elegans model of Duchenne muscular dystrophy reveals a potential role for disrupted sulfur metabolism in the disease and thus the therapeutic potential of sulfur amino acid supplementation.
Externí odkaz:
https://doaj.org/article/4432ccd0b65f49109ae3ad1c72d1ed33
Autor:
Rosangela Montanaro, Valentina Vellecco, Roberta Torregrossa, Gian Marco Casillo, Onorina Laura Manzo, Emma Mitidieri, Mariarosaria Bucci, Sigismondo Castaldo, Raffaella Sorrentino, Matthew Whiteman, Martina Smimmo, Flavia Carriero, Giuseppe Terrazzano, Giuseppe Cirino, Roberta d’Emmanuele di Villa Bianca, Vincenzo Brancaleone
Publikováno v:
Redox Biology, Vol 62, Iss , Pp 102657- (2023)
Diabetes is associated with severe vascular complications involving the impairment of endothelial nitric oxide synthase (eNOS) as well as cystathionine γ-lyase (CSE) activity. eNOS function is suppressed in hyperglycaemic conditions, resulting in re
Externí odkaz:
https://doaj.org/article/cfd68478f66f44dd8c2212be1e351e68
Autor:
Zsolt Combi, László Potor, Péter Nagy, Katalin Éva Sikura, Tamás Ditrói, Eszter Petra Jurányi, Klaudia Galambos, Tamás Szerafin, Péter Gergely, Matthew Whiteman, Roberta Torregrossa, Yuchao Ding, Lívia Beke, Zoltán Hendrik, Gábor Méhes, György Balla, József Balla
Publikováno v:
Redox Biology, Vol 60, Iss , Pp 102629- (2023)
Hydrogen sulfide (H2S) was previously revealed to inhibit osteoblastic differentiation of valvular interstitial cells (VICs), a pathological feature in calcific aortic valve disease (CAVD). This study aimed to explore the metabolic control of H2S lev
Externí odkaz:
https://doaj.org/article/a3796fa1603843a4bad5792c6dc90283
Hydrogen Sulfide Is a Novel Protector of the Retinal Glycocalyx and Endothelial Permeability Barrier
Autor:
Claire L. Allen, Katarzyna Wolanska, Naseeb K. Malhi, Andrew V. Benest, Mark E. Wood, Winfried Amoaku, Roberta Torregrossa, Matthew Whiteman, David O. Bates, Jacqueline L. Whatmore
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Significantly reduced levels of the anti-inflammatory gaseous transmitter hydrogen sulfide (H2S) are observed in diabetic patients and correlate with microvascular dysfunction. H2S may protect the microvasculature by preventing loss of the endothelia
Externí odkaz:
https://doaj.org/article/045343c009d94e33ab351eef1c22e116
Autor:
Silvijus Abramavicius, Asbjørn G. Petersen, Nirthika S. Renaltan, Judit Prat-Duran, Roberta Torregrossa, Edgaras Stankevicius, Matthew Whiteman, Ulf Simonsen
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Donors of H2S may be beneficial in treating cardiovascular diseases where the plasma levels of H2S are decreased. Therefore, we investigated the mechanisms involved in relaxation of small arteries induced by GYY4137 [(4-methoxyphenyl)-morpholin-4-yl-
Externí odkaz:
https://doaj.org/article/9520b73c5b3e4adcb7efa3c93f805d02
Autor:
Leonardo A. da Costa Marques, Simone A. Teixeira, Flávia N. de Jesus, Mark E. Wood, Roberta Torregrossa, Matthew Whiteman, Soraia K. P. Costa, Marcelo N. Muscará
Publikováno v:
Biomolecules, Vol 12, Iss 2, p 280 (2022)
Mitochondria-targeted hydrogen sulfide (H2S) donor compounds, such as compound AP39, supply H2S into the mitochondrial environment and have shown several beneficial in vitro and in vivo effects in cardiovascular conditions such as diabetes and hypert
Externí odkaz:
https://doaj.org/article/090d262621ec4e529db2e1099e9de8e8
Autor:
Katarzyna Magierowska, Edyta Korbut, Dagmara Wójcik-Grzybek, Dominik Bakalarz, Zbigniew Sliwowski, Jakub Cieszkowski, Małgorzata Szetela, Roberta Torregrossa, Matthew Whiteman, Marcin Magierowski
Publikováno v:
Journal of Controlled Release. 348:321-334
Hydrogen sulfide (H
Autor:
Bartosz Pomierny, Weronika Krzyżanowska, Jakub Jurczyk, Alicja Skórkowska, Beata Strach, Małgorzata Szafarz, Katarzyna Przejczowska-Pomierny, Roberta Torregrossa, Matthew Whiteman, Monika Marcinkowska, Joanna Pera, Bogusława Budziszewska
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 15, p 7816 (2021)
Ischemic stroke is the third leading cause of death in the world, which accounts for almost 12% of the total deaths worldwide. Despite decades of research, the available and effective pharmacotherapy is limited. Some evidence underlines the beneficia
Externí odkaz:
https://doaj.org/article/1bcfd4f136764e7a8abd5fc3b1adc611
Autor:
Uraiwan Panich, Malinee Saelim, Weerawon Thangboonjit, Anyamanee Chaiprasongsuk, Matthew Whiteman, Roberta Torregrossa, Saowanee Jeayeng, Jinapath Lohakul, Mark E. Wood
Publikováno v:
Antioxidants & Redox Signaling. 36:1268-1288
Aims: Oxidative stress and mitochondrial dysfunction play a role in the process of skin photoaging via activation of matrix metalloproteases (MMPs) and the subsequent degradation of collagen. The a...