Výsledky vyhledávání - "Roberta, Krüger"

Synthesis of sulfamoyl-triazolyl-carboxamides as pharmacological myeloperoxidase inhibitors

Autor: Allya Larroza, Roberta Krüger, Mariana G. Fronza, Ana Paula Pesarico, Daniela H. de Oliveira, Lucielli Savegnago, Diego Alves

Publikováno v: New Journal of Chemistry. 46:12358-12366

Sulfamoyl-triazolyl-carboxamides were synthesized using DBU as a catalyst, and their molecular docking and MPO activity analyses were performed.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::43753b64b11f9a91e9933be001d72d1e
https://doi.org/10.1039/d2nj01926d

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The neurotherapeutic role of a selenium-functionalized quinoline in hypothalamic obese rats

Autor: Ethel A. Wilhelm, Cristiani F. Bortolatto, Roberta Krüger, Diego Alves, Silvana Peterini Boeira, Renata L. de Oliveira, Silvane Souza Roman, Jaini J. Paltian, Cristiane Luchese, Ketlyn P. da Motta, Karline da Costa Rodrigues

Publikováno v: Psychopharmacology. 238:1937-1951

Obesity is considered one of the major global health problems and increases the risk of several medical complications, such as diabetes and mental illnesses. The present study investigated the effect of 7-chloro-4-(phenylselanyl) quinoline (4-PSQ) on

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::00d00584c9447e63b8c6bde01c666202
https://doi.org/10.1007/s00213-021-05821-y

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Synthesis, photophysics and biomolecule interactive studies of new hybrid benzo-2,1,3-thiadiazoles

Autor: Lucielli Savegnago, Bernardo A. Iglesias, Mariana G. Fronza, Robson S. Oliboni, Roberta Krüger, Thiago V. Acunha, Renata A. Balaguez, José S. S. Neto, Diego Alves

Publikováno v: New Journal of Chemistry. 44:2768-2780

Four new hybrid molecules containing benzo-2,1,3-thiadiazole, benzofuran and arylselanyl moieties, named 4,7-bis(3-(arylselanyl)benzofuran-2-yl)benzo[c][1,2,5]thiadiazoles, were designed and synthesized in good yields through an electrophilic cycliza

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::74ac7ff71698c85148e3efb97fb3a573
https://doi.org/10.1039/c9nj05932f

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Bis-triazolylchalcogenium-Functionalized Benzothiadiazole Derivatives as Light-up Sensors for DNA and BSA

Autor: Isadora Tisoco, Bernardo A. Iglesias, Diego Alves, Allya Larroza, Lucielli Savegnago, Joel S. Reis, Mariana G. Fronza, Davi F. Back, Roberta Krüger

Publikováno v: The Journal of organic chemistry. 86(24)

A range of bis-triazolylchalcogenium-BTD 3 was synthesized by a copper-catalyzed azide-alkyne cycloaddition of azido arylchalcogenides 1 and 4,7-diethynylbenzo[c][1,2,5]thiadiazole 2. Eight new compounds were obtained in moderate to good yields using

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06cabfd398d0d9e5eac9065e2207bcca
https://pubmed.ncbi.nlm.nih.gov/34843245

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Fluorescent Benzoselenadiazoles: Synthesis, Characterization, and Quantification of Intracellular Lipid Droplets and Multicellular Model Staining

Autor: Thiago O. Lopes, José R. Corrêa, Brenno A. D. Neto, Roberta Krüger, Diego Alves, Ana Luisa Augusto Barbosa, Heibbe C. B. de Oliveira, Renata A. Balaguez, Ingryd R. Medeiros

Publikováno v: The Journal of organic chemistry. 85(16)

In this work, we described the synthesis of 10 new fluorescent 2,1,3-benzoselenadiazole small-molecule derivatives and their chemical- and photocharacterizations. The new derivatives could, for the first time, be successfully applied as selective liv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c93149d17ad3f4225952b5a82074674
https://pubmed.ncbi.nlm.nih.gov/32806092

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The neurotherapeutic role of a selenium-functionalized quinoline in hypothalamic obese rats

Autor: Karline C, Rodrigues, Cristiani F, Bortolatto, Ketlyn P, da Motta, Renata L, de Oliveira, Jaini J, Paltian, Roberta, Krüger, Silvane S, Roman, Silvana P, Boeira, Diego, Alves, Ethel Antunes, Wilhelm, Cristiane, Luchese

Publikováno v: Psychopharmacology. 238(7)

Obesity is considered one of the major global health problems and increases the risk of several medical complications, such as diabetes and mental illnesses.The present study investigated the effect of 7-chloro-4-(phenylselanyl) quinoline (4-PSQ) on

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0a4259fc829ac4a214d0c1d7362bbad7
https://pubmed.ncbi.nlm.nih.gov/33740091

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The anxiolytic effect of a promising quinoline containing selenium with the contribution of the serotonergic and GABAergic pathways: Modulation of parameters associated with anxiety in mice

Autor: Angélica S. Reis, Jaini J. Paltian, Renata L. de Oliveira, Ethel A. Wilhelm, Eduardo N. Dellagostin, Cristiane Luchese, Vinicius Farias Campos, Diego Alves, William Borges Domingues, Roberta Krüger, Caren A.R. da Fonseca

Publikováno v: Behavioural Brain Research. 393:112797

Recently, we demonstrated the promising anxiolytic action of 7-chloro-4-(phenylselanyl) quinoline (4-PSQ) in mice. For this reason, the objective of this study was to expand our previous findings by investigating the contribution of serotoninergic an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a510c3533b9c82155cee5b9af91d57dd
https://doi.org/10.1016/j.bbr.2020.112797

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7-Chloro-4-(Phenylselanyl) Quinoline with Memory Enhancer Action in Aging Rats: Modulation of Neuroplasticity, Acetylcholinesterase Activity, and Cholesterol Levels

Autor: Angélica S. Reis, Simone Pinton, Ethel A. Wilhelm, Vinicius Farias Campos, Roberta Krüger, Diego Alves, Ane G. Vogt, Cristiane Luchese, Natália Paroul, Mikaela P. Pinz, Anelise Barth, William Borges Domingues

Publikováno v: Molecular neurobiology. 56(9)

This study investigated the effect of 7-chloro-4-(phenylselanyl) quinoline (4-PSQ) to restore the cognitive impairment caused by aging in male Wistar rats. Moreover, modulation of neuroplasticity markers, acetylcholinesterase (AChE) activity, and cho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::204060aefe8cca7bde3f6838817e2766
https://pubmed.ncbi.nlm.nih.gov/30805835

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