Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Roberta, Foresti"'
Autor:
Pooja Pradhan, Vijith Vijayan, Bin Liu, Beatriz Martinez-Delgado, Nerea Matamala, Christoph Nikolin, Robert Greite, David S. DeLuca, Sabina Janciauskiene, Roberto Motterlini, Roberta Foresti, Stephan Immenschuh
Publikováno v:
Redox Biology, Vol 73, Iss , Pp 103191- (2024)
Activation of inflammation is tightly associated with metabolic reprogramming in macrophages. The iron-containing tetrapyrrole heme can induce pro-oxidant and pro-inflammatory effects in murine macrophages, but has been associated with polarization t
Externí odkaz:
https://doaj.org/article/10beebca8286441e863a90e32e3854fe
Autor:
Christina Morgenstern, Isabel Lastres-Becker, Birsen Can Demirdöğen, Vera Marisa Costa, Andreas Daiber, Roberta Foresti, Roberto Motterlini, Sibel Kalyoncu, Burak I. Arioz, Sermin Genc, Monika Jakubowska, Ioannis P. Trougakos, Aleksandra Piechota-Polanczyk, Michel Mickael, Marlene Santos, Thomas W. Kensler, Antonio Cuadrado, Ian M. Copple
Publikováno v:
Redox Biology, Vol 72, Iss , Pp 103134- (2024)
The cytoprotective transcription factor NRF2 regulates the expression of several hundred genes in mammalian cells and is a promising therapeutic target in a number of diseases associated with oxidative stress and inflammation. Hence, an ability to mo
Externí odkaz:
https://doaj.org/article/f50d81e6b4e544bc8942767d3919a61a
Autor:
Djamal Eddine Benrahla, Shruti Mohan, Matija Trickovic, Florence Anne Castelli, Ghida Alloul, Arielle Sobngwi, Rosa Abdiche, Silas Kieser, Vanessa Demontant, Elisabeth Trawinski, Céline Chollet, Christophe Rodriguez, Hiroaki Kitagishi, François Fenaille, Mirko Trajkovski, Roberto Motterlini, Roberta Foresti
Publikováno v:
Redox Biology, Vol 72, Iss , Pp 103153- (2024)
Carbon monoxide (CO), a gaseous signaling molecule, has shown promise in preventing body weight gain and metabolic dysfunction induced by high fat diet (HFD), but the mechanisms underlying these effects are largely unknown. An essential component in
Externí odkaz:
https://doaj.org/article/03980ef3114847fd9157b9c2144372c5
Autor:
Shruti Mohan, Louis-Antoine Barel, Djamal Eddine Benrahla, Bernard Do, Qiyue Mao, Hiroaki Kitagishi, Michael Rivard, Roberto Motterlini, Roberta Foresti
Publikováno v:
Pharmacological Research, Vol 191, Iss , Pp 106770- (2023)
Metal carbonyls have been developed as carbon monoxide-releasing molecules (CO-RMs) to deliver CO for therapeutic purposes. The manganese-based CORM-401 has been recently reported to exert beneficial effects in obese animals by reducing body weight g
Externí odkaz:
https://doaj.org/article/e508d3eb7d174583b8fa572062e24b22
Autor:
Qiyue Mao, Akira T. Kawaguchi, Shun Mizobata, Roberto Motterlini, Roberta Foresti, Hiroaki Kitagishi
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Mao et al. report highly sensitive quantification of carbon monoxide with a simple colorimetric assay, exploiting a synthetic supramolecular compound, hemoCD1. It can reveal distribution of CO in organs including the brain and can also serve as a CO
Externí odkaz:
https://doaj.org/article/4b1f78dee8e74f8090c69506a80dd15a
Autor:
Pooja Pradhan, Vijith Vijayan, Karsten Cirksena, Falk F.R. Buettner, Kazuhiko Igarashi, Roberto Motterlini, Roberta Foresti, Stephan Immenschuh
Publikováno v:
Redox Biology, Vol 51, Iss , Pp 102265- (2022)
BTB-and-CNC homologue 1 (BACH1), a heme-regulated transcription factor, mediates innate immune responses via its functional role in macrophages. BACH1 has recently been shown to modulate mitochondrial metabolism in cancer cells. In the current study,
Externí odkaz:
https://doaj.org/article/7738e9384c5b4f329f0a62b02ecf0a0e
Autor:
Laura Le Pelletier, Matthieu Mantecon, Jennifer Gorwood, Martine Auclair, Roberta Foresti, Roberto Motterlini, Mireille Laforge, Michael Atlan, Bruno Fève, Jacqueline Capeau, Claire Lagathu, Veronique Bereziat
Publikováno v:
eLife, Vol 10 (2021)
Aging is associated with central fat redistribution and insulin resistance. To identify age-related adipose features, we evaluated the senescence and adipogenic potential of adipose-derived stromal cells (ASCs) from abdominal subcutaneous fat obtaine
Externí odkaz:
https://doaj.org/article/6426a1846c5b47f480f27f4a3ce2239c
Autor:
Roberto Motterlini, Aniket Nikam, Sylvie Manin, Anthony Ollivier, Jayne Louise Wilson, Sabrina Djouadi, Lucie Muchova, Thierry Martens, Michael Rivard, Roberta Foresti
Publikováno v:
Redox Biology, Vol 20, Iss , Pp 334-348 (2019)
Oxidative stress and inflammation are predominant features of several chronic diseases. The nuclear factor erythroid 2-related factor 2 (Nrf2) is a major arbiter in counteracting these insults via up-regulation of several defensive proteins, includin
Externí odkaz:
https://doaj.org/article/c40ef74f08d945e9afc8c28944f8784d
Autor:
Laura Braud, Maria Pini, Donald F. Stec, Sylvie Manin, Geneviève Derumeaux, David E. Stec, Roberta Foresti, Roberto Motterlini
Publikováno v:
Redox Biology, Vol 38, Iss , Pp 101805- (2021)
Obesity is associated with metabolic dysregulation characterized by insulin resistance and glucose intolerance. Nuclear factor E2-related factor (Nrf2) is a critical regulator of the stress response and Nrf2-deficient mice (Nrf2−/−) are protected
Externí odkaz:
https://doaj.org/article/4be0788209394dea88047c5fa013dfa1
Autor:
Kenza Ngono Ayissi, Jennifer Gorwood, Laura Le Pelletier, Christine Bourgeois, Carine Beaupère, Martine Auclair, Roberta Foresti, Roberto Motterlini, Michael Atlan, Aurélie Barrail-Tran, Roger Le Grand, Delphine Desjardins, Bruno Fève, Olivier Lambotte, Jacqueline Capeau, Véronique Béréziat, Claire Lagathu
Publikováno v:
Cells, Vol 11, Iss 11, p 1841 (2022)
For people living with HIV, treatment with integrase-strand-transfer-inhibitors (INSTIs) can promote adipose tissue (AT) gain. We previously demonstrated that INSTIs can induce hypertrophy and fibrosis in AT of macaques and humans. By promoting energ
Externí odkaz:
https://doaj.org/article/55ba594c6daf431e8bcdf4805ef78500