Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Roberta, Borghi"'
Autor:
Raffaella Mastrocola, Michela Guglielmotto, Claudio Medana, Maria Graziella Catalano, Santina Cutrupi, Roberta Borghi, Elena Tamagno, Giuseppe Boccuzzi, Manuela Aragno
Publikováno v:
Neurobiology of Disease, Vol 44, Iss 1, Pp 116-124 (2011)
β-Amyloid hyperproduction has been observed in response to alterations in neuronal intracellular cholesterol storage, efflux, and synthesis, induced in rats by a high-fat diet. It has been suggested that cholesterol homeostasis is altered in Alzheim
Externí odkaz:
https://doaj.org/article/b75b2062afd84b1f8236e5edb4dcf460
Autor:
Sara Massone, Irene Vassallo, Gloria Fiorino, Manuele Castelnuovo, Federica Barbieri, Roberta Borghi, Massimo Tabaton, Mauro Robello, Elena Gatta, Claudio Russo, Tullio Florio, Giorgio Dieci, Ranieri Cancedda, Aldo Pagano
Publikováno v:
Neurobiology of Disease, Vol 41, Iss 2, Pp 308-317 (2011)
Alternative splicing is a central component of human brain complexity; nonetheless, its regulatory mechanisms are still largely unclear. In this work, we describe a novel non-coding (nc) RNA (named 17A) RNA polymerase (pol) III-dependent embedded in
Externí odkaz:
https://doaj.org/article/86e6db654bc14977b656f5a4e3fe1545
Autor:
Alessandra Piccini, Anna Fassio, Elena Pasqualetto, Antonella Vitali, Roberta Borghi, Daniela Palmieri, Benedetta Nacmias, Sandro Sorbi, Roberto Sitia, Massimo Tabaton
Publikováno v:
Neurobiology of Disease, Vol 15, Iss 2, Pp 380-386 (2004)
Many patients affected by early onset familial Alzheimer's disease (FAD), carry mutations in the presenilin 1 (PS1) gene. Since it has been suggested that FAD-linked PS1 mutations impair the unfolded protein response (UPR) due to endoplasmic reticulu
Externí odkaz:
https://doaj.org/article/b2ca97ac89ff4dbfa38e0aa04dc487c0
Autor:
Elena Tamagno, Paola Bardini, Alessandra Obbili, Antonella Vitali, Roberta Borghi, Damiano Zaccheo, Maria A. Pronzato, Oliviero Danni, Mark A. Smith, George Perry, Massimo Tabaton
Publikováno v:
Neurobiology of Disease, Vol 10, Iss 3, Pp 279-288 (2002)
Recently an aspartyl protease with β-secretase activity called BACE was identified. In the present paper we showed that BACE is modulated by the oxidative stress product 4-hydroxynonenal (HNE). Exposure of NT2 neurons to the two classical pro-oxidan
Externí odkaz:
https://doaj.org/article/9f2bf446cb9a48cfb665296275e4ef51
Autor:
Roberta Borghi, Nicola Traverso, Liviana Prola, Fiammetta Monacelli, Patrizio Odetti, Andrea Bovero, Emanuela Valle, Joana Nery, Achille Schiavone, Diana Vergnano, Natascia Bruni, Domenico Bergero
Publikováno v:
Journal of Feline Medicine and Surgery. 21:465-474
ObjectivesCats are commonly affected by chronic kidney disease (CKD). Many reactive carbonyl intermediates and end products originating from the oxidative stress pathways are recognised as uraemic toxins and may play a role in CKD progression. The ai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a890b103598e68cf5bb8a08319ac7d0b
https://doi.org/10.1177/1098612x18783858
https://doi.org/10.1177/1098612x18783858
From a biological point of view, aging can be considered a progressive inability of an organism to react to stress, maintain homeostasis, and survive unfavourable changes during post-maturational life. The expression of several adipokines changes dur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd9d81ff86896f6b5f26d21fb5921a25
http://hdl.handle.net/11567/936205
http://hdl.handle.net/11567/936205
Autor:
Alessio Nencioni, V. Bassoli, Roberta Borghi, Fiammetta Monacelli, A. L. Biagini, F. Torre, Michele Cea, Patrizio Odetti, D. Becchetti, Marina Sartini
Publikováno v:
The journal of nutrition, health & aging. 21:614-621
The aim of the present study was to validate the photographic indirect method as an accurate and specific tool to assess nutritional intake in a cohort of elderly hospitalized patients. this is a prospective observational study. hospital (geriatric a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cddc0c549bcb6e8e4f57611218533ce1
https://doi.org/10.1007/s12603-016-0814-y
https://doi.org/10.1007/s12603-016-0814-y
Autor:
Elena Tamagno, Massimo Tabaton, Ottavio Arancio, Patrizio Odetti, Laura Colombo, Roberta Borghi, Raluca Zamfir, Michela Guglielmotto, Giusi Manassero, Mario Salmona, George Perry
Publikováno v:
Aging Cell
Summary The mechanistic relationship between amyloid β1‐42 (Aβ1‐42) and the alteration of Tau protein are debated. We investigated the effect of Aβ1‐42 monomers and oligomers on Tau, using mice expressing wild‐type human Tau that do not sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c193e5119ed85ec3bce29dde81871b1
https://doi.org/10.1111/acel.12500
https://doi.org/10.1111/acel.12500
Autor:
Fabrizio Montecucco, Roberta Borghi, Alessio Nencioni, Manuela Tafuro, Luigi Molfetta, Marina Sartini, Michele Cea, Patrizio Odetti, Fiammetta Monacelli
Publikováno v:
Geriatrics & Gerontology International. 17:1015-1021
Aim Prognosis informs the physician's decision-making process, especially for frail older adults. So far, any non-disease-specific index has proven full evidence for routine use in clinical practice. Here, we aimed at assessing, prospectively, the ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::354573dfbe7b16b24c8e3a550c79ebaf
https://doi.org/10.1111/ggi.12801
https://doi.org/10.1111/ggi.12801