Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Robert. M. Caudle"'
Autor:
Ariana C. Brice-Tutt, Darrice S. Montgomery, Cassidy M. Kramer, Peter M. Novotny, Wendi L. Malphurs, Abhisheak Sharma, Robert. M. Caudle, Adriaan W. Bruijnzeel, Barry Setlow, John K. Neubert, Niall P. Murphy
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Inter-relationships between pain sensitivity, drug reward, and drug misuse are of considerable interest given that many analgesics exhibit misuse potential. Here we studied rats as they underwent a series of pain- and reward-related tests: c
Externí odkaz:
https://doaj.org/article/1425e38455d0434487e5d384057c23da
Autor:
Robert M. Caudle, John K. Neubert
Publikováno v:
Frontiers in Pain Research, Vol 3 (2022)
The chemotherapeutic agent oxaliplatin is commonly used to treat colorectal cancer. Although effective as a chemotherapeutic, it frequently produces painful peripheral neuropathies. These neuropathies can be divided into an acute sensitivity to cool
Externí odkaz:
https://doaj.org/article/92a40131426d4cf994ce39c5ca369eb1
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/0e5cf137ee324a92983f73459946053b
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Rodent models of human disease can be valuable for understanding the mechanisms of a disease and for identifying novel therapies. However, it is critical that these models be vetted prior to committing resources to developing novel therapeutics. Fail
Externí odkaz:
https://doaj.org/article/eb4f6057fa354b729b0a00512380d340
Autor:
Adriaan W. Bruijnzeel, Azin Behnood-Rod, Wendi Malphurs, Ranjithkumar Chellian, Robert M. Caudle, Marcelo Febo, Barry Setlow, John K. Neubert
Publikováno v:
Behavioural Pharmacology. 33:418-426
The prescription opioid oxycodone is widely used for the treatment of pain in humans. Oxycodone misuse is more common among people with an anxiety disorder than those without one. Therefore, oxycodone might be misused for its anxiolytic properties. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d147c8c162b654e71da17f854b093b77
https://doi.org/10.1097/fbp.0000000000000690
https://doi.org/10.1097/fbp.0000000000000690
Autor:
Niall P. Murphy, Darrice S. Montgomery, Ariana C. Brice-Tutt, Cassidy M. Kramer, Peter M. Novotny, Wendi Malphurs, Robert M. Caudle, Adriaan W. Bruijnzeel, Abhisheak Sharma, Barry Setlow, John K. Neubert
Inter-relationships between pain sensitivity, drug reward, and drug misuse are of considerable interest given that many analgesics exhibit misuse potential. Here we studied rats as they underwent a series of pain- and reward-related tests: cutaneous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78a0dbab4b038365d0cb938bb9755add
https://doi.org/10.21203/rs.3.rs-2679319/v1
https://doi.org/10.21203/rs.3.rs-2679319/v1
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0176753 (2017)
The detection of cool temperatures is thought to be mediated by primary afferent neurons that express the cool temperature sensing protein Transient Receptor Potential Cation Channel, Subfamily M, Member 8 (TRPM8). Using mice, this study tested the h
Externí odkaz:
https://doaj.org/article/aa42f2dca2f1489db64f3a75d07ee5e2
Autor:
Basak Donertas-Ayaz, Robert M. Caudle
Publikováno v:
Neurobiology of Pain. 13:100124
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::42c9b55c43cb11baa43206bc8920255f
https://doi.org/10.1016/j.ynpai.2023.100124
https://doi.org/10.1016/j.ynpai.2023.100124
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e89137 (2014)
Transient receptor potential (TRP) cation channels are involved in the perception of hot and cold pain and are targets for pain relief in humans. We hypothesized that agonists of TRPV1 and TRPM8/TRPA1, capsaicin and menthol, would alter nociceptive b
Externí odkaz:
https://doaj.org/article/e291ec074a114b089e206c0e2d21a906
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Frontiers in Pharmacology
Frontiers in Pharmacology
Rodent models of human disease can be valuable for understanding the mechanisms of a disease and for identifying novel therapies. However, it is critical that these models be vetted prior to committing resources to developing novel therapeutics. Fail
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41ce6f0f63d8c50e54e932fc5036eac7
https://www.frontiersin.org/articles/10.3389/fphar.2020.527495/full
https://www.frontiersin.org/articles/10.3389/fphar.2020.527495/full