Zobrazeno 1 - 10
of 126
pro vyhledávání: '"Robert-Jan Lebbink"'
Autor:
Ningning Ma, Mengjia Zhang, Jiaru Zhou, Changsheng Jiang, Ahmed H. Ghonaim, Yumei Sun, Pei Zhou, Guanghao Guo, Anouk Evers, Hongmei Zhu, Qigai He, Robert Jan Lebbink, Berend Jan Bosch, Wentao Li
Publikováno v:
Emerging Microbes and Infections, Vol 13, Iss 1 (2024)
Porcine deltacoronavirus (PDCoV) is an emerging pathogen that can cause severe diarrhoea and high mortality in suckling piglets. Moreover, evidence of PDCoV infection in humans has raised concerns regarding potential public health risks. To identify
Externí odkaz:
https://doaj.org/article/dccec0b415754fbfb680ec7d6e015876
Autor:
Annefleur C. Langedijk, Bram Vrancken, Robert Jan Lebbink, Deidre Wilkins, Elizabeth J. Kelly, Eugenio Baraldi, Abiel Homero Mascareñas de Los Santos, Daria M. Danilenko, Eun Hwa Choi, María Angélica Palomino, Hsin Chi, Christian Keller, Robert Cohen, Jesse Papenburg, Jeffrey Pernica, Anne Greenough, Peter Richmond, Federico Martinón-Torres, Terho Heikkinen, Renato T. Stein, Mitsuaki Hosoya, Marta C. Nunes, Charl Verwey, Anouk Evers, Leyla Kragten-Tabatabaie, Marc A. Suchard, Sergei L. Kosakovsky Pond, Chiara Poletto, Vittoria Colizza, Philippe Lemey, Louis J. Bont, on behalf of the INFORM-RSV Study Group
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Respiratory syncytial virus (RSV) is a leading cause of acute lower respiratory tract infection in young children and the second leading cause of infant death worldwide. While global circulation has been extensively studied for respiratory v
Externí odkaz:
https://doaj.org/article/45e7038869c54007951a43a1f120bf0b
Autor:
Ylenia Longo, Sara Moreno Mascaraque, Giuseppe Andreacchio, Julia Werner, Ichiro Katahira, Elena De Marchi, Anna Pegoraro, Robert Jan Lebbink, Karl Köhrer, Patrick Petzsch, Ronny Tao, Francesco Di Virgilio, Elena Adinolfi, Ingo Drexler
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionModified Vaccinia Virus Ankara (MVA) is a safe vaccine vector inducing long- lasting and potent immune responses. MVA-mediated CD8+T cell responses are optimally induced, if both, direct- and cross-presentation of viral or recombinant ant
Externí odkaz:
https://doaj.org/article/c51d0799a12d4c9e9a19762506b18869
Autor:
Tom Cremer, Hanneke Hoelen, Michael L van de Weijer, George M Janssen, Ana I Costa, Peter A van Veelen, Robert Jan Lebbink, Emmanuel J H J Wiertz
Publikováno v:
PLoS ONE, Vol 19, Iss 5, p e0287877 (2024)
Type 1 diabetes (T1D) is characterized by HLA class I-mediated presentation of autoantigens on the surface of pancreatic β-cells. Recognition of these autoantigens by CD8+ T cells results in the destruction of pancreatic β-cells and, consequently,
Externí odkaz:
https://doaj.org/article/e120816276044d81a6197f415591e794
Autor:
Annefleur C. Langedijk, Robert Jan Lebbink, Christiana Naaktgeboren, Anouk Evers, Marco C. Viveen, Anne Greenough, Terho Heikkinen, Renato T. Stein, Peter Richmond, Federico Martinón-Torres, Marta Nunes, Mitsuaki Hosoya, Christian Keller, Monika Bauck, Robert Cohen, Jesse Papenburg, Jeffrey Pernica, Marije P. Hennus, Hong Jin, David E. Tabor, Andrev Tovchigrechko, Alexey Ruzin, Michael E. Abram, Deidre Wilkins, Joanne G. Wildenbeest, Leyla Kragten-Tabatabaie, Frank E. J. Coenjaerts, Mark T. Esser, Louis J. Bont
Publikováno v:
BMC Infectious Diseases, Vol 20, Iss 1, Pp 1-8 (2020)
Abstract Background Respiratory syncytial virus (RSV) is a global cause of severe respiratory morbidity and mortality in infants. While preventive and therapeutic interventions are being developed, including antivirals, vaccines and monoclonal antibo
Externí odkaz:
https://doaj.org/article/7dca7f74e743453a86b509c336fc6ee6
Autor:
Mitchell Evers, Toine Ten Broeke, J.H. Marco Jansen, Maaike Nederend, Firas Hamdan, Karli R. Reiding, Saskia Meyer, Petra Moerer, Iris Brinkman, Thies Rösner, Robert Jan Lebbink, Thomas Valerius, Jeanette H.W. Leusen
Publikováno v:
mAbs, Vol 12, Iss 1 (2020)
Current combination therapies elicit high response rates in B cell malignancies, often using CD20 antibodies as the backbone of therapy. However, many patients eventually relapse or develop progressive disease. Therefore, novel CD20 antibodies combin
Externí odkaz:
https://doaj.org/article/d9265821ed1e409289b5df381031fef1
Autor:
Shirley E. Braspenning, Robert Jan Lebbink, Daniel P. Depledge, Claudia M. E. Schapendonk, Laura A. Anderson, Georges M. G. M. Verjans, Tomohiko Sadaoka, Werner J. D. Ouwendijk
Publikováno v:
Viruses, Vol 13, Iss 11, p 2289 (2021)
Primary varicella-zoster virus (VZV) infection leads to varicella and the establishment of lifelong latency in sensory ganglion neurons. Reactivation of latent VZV causes herpes zoster, which is frequently associated with chronic pain. Latent viral g
Externí odkaz:
https://doaj.org/article/96301de7e9954e899fc81bcb79e193cc
Autor:
Zsolt Sebestyen, Wouter Scheper, Anna Vyborova, Siyi Gu, Zuzana Rychnavska, Marleen Schiffler, Astrid Cleven, Coraline Chéneau, Martje van Noorden, Cassie-Marie Peigné, Daniel Olive, Robert Jan Lebbink, Rimke Oostvogels, Tuna Mutis, Gerrit Jan Schuurhuis, Erin J. Adams, Emmanuel Scotet, Jürgen Kuball
Publikováno v:
Cell Reports, Vol 15, Iss 9, Pp 1973-1985 (2016)
Human Vγ9Vδ2 T cells respond to tumor cells by sensing elevated levels of phosphorylated intermediates of the dysregulated mevalonate pathway, which is translated into activating signals by the ubiquitously expressed butyrophilin A1 (BTN3A1) throug
Externí odkaz:
https://doaj.org/article/2db78a3619e04870be1de1e42066352c
Autor:
Christian K. Holm, Stine H. Rahbek, Hans Henrik Gad, Rasmus O. Bak, Martin R. Jakobsen, Zhaozaho Jiang, Anne Louise Hansen, Simon K. Jensen, Chenglong Sun, Martin K. Thomsen, Anders Laustsen, Camilla G. Nielsen, Kasper Severinsen, Yingluo Xiong, Dara L. Burdette, Veit Hornung, Robert Jan Lebbink, Mogens Duch, Katherine A. Fitzgerald, Shervin Bahrami, Jakob Giehm Mikkelsen, Rune Hartmann, Søren R. Paludan
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
Stimulator of interferon genes (STING) is known to be involved in defence against DNA viruses, but its role in the control of RNA viruses remains poorly explored. Here the authors show that STING participates in an innate immune response to RNA virus
Externí odkaz:
https://doaj.org/article/00f2e460d4a44590a591e3a422a9f087
Autor:
Deidre Wilkins, Annefleur C Langedijk, Robert Jan Lebbink, Christopher Morehouse, Michael E Abram, Bahar Ahani, Anastasia A Aksyuk, Eugenio Baraldi, Tyler Brady, Albert Tian Chen, Hsin Chi, Eun Hwa Choi, Robert Cohen, Daria M Danilenko, Vancheswaran Gopalakrishnan, Anne Greenough, Terho Heikkinen, Mitsuaki Hosoya, Christian Keller, Elizabeth J Kelly, Leyla Kragten-Tabatabaie, Federico Martinón-Torres, Abiel Homero Mascareñas de Los Santos, Marta C Nunes, María Angélica Palomino, Jesse Papenburg, Jeffrey M Pernica, Peter Richmond, Renato T Stein, Kevin M Tuffy, Charl Verwey, Mark T Esser, David E Tabor, Louis J Bont, Pascale Clement, Atul Gupta, Koichi Hashimoto, Kseniya Komissarova, Matt Laubscher, Magali Lumertz, Elena Priante, Irene Rivero-Calle, Ushma Wadia, Ki Wook Yun
Publikováno v:
The Lancet Infectious Diseases.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94b9df76477908bede262936e17c70dd
https://doi.org/10.1016/s1473-3099(23)00062-2
https://doi.org/10.1016/s1473-3099(23)00062-2