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Autor:
Alyaa M. Abdel-Haleem, Robert van der Weerd, Connie R. Jimenez, Moataz Abd El Ghany, Louis S. Ates, Marion Sparrius, Sander R. Piersma, Rainer Kalscheuer, Eveline M. Weerdenburg, Arnab Pain, Roy Ummels, Abdallah M. Abdallah, Wilbert Bitter, Marina Alber, Edith N.G. Houben, Susanna Commandeur
Publikováno v:
PLoS Genetics
PLoS Genetics, 4(11):5. Public Library of Science
PLoS Genetics, Vol 11, Iss 5, p e1005190 (2015)
Ates, L S, Ummels, R, Commandeur, S, van de Weerd, R, Sparrius, M, Weerdenburg, E, Alber, M, Kalscheuer, R, Piersma, S R, Abdallah, A, Abd El Ghany, M, Abdel-Haleem, A M, Pain, A, Jimenez, C R, Bitter, W & Houben, E N G 2015, ' Essential Role of the ESX-5 Secretion System in Outer Membrane Permeability of Pathogenic Mycobacteria. ', PLoS Genetics, vol. 4, no. 11, 5 . https://doi.org/10.1371/journal.pgen.1005190
PLoS Genetics, 4(11):5. Public Library of Science
PLoS Genetics, Vol 11, Iss 5, p e1005190 (2015)
Ates, L S, Ummels, R, Commandeur, S, van de Weerd, R, Sparrius, M, Weerdenburg, E, Alber, M, Kalscheuer, R, Piersma, S R, Abdallah, A, Abd El Ghany, M, Abdel-Haleem, A M, Pain, A, Jimenez, C R, Bitter, W & Houben, E N G 2015, ' Essential Role of the ESX-5 Secretion System in Outer Membrane Permeability of Pathogenic Mycobacteria. ', PLoS Genetics, vol. 4, no. 11, 5 . https://doi.org/10.1371/journal.pgen.1005190
Mycobacteria possess different type VII secretion (T7S) systems to secrete proteins across their unusual cell envelope. One of these systems, ESX-5, is only present in slow-growing mycobacteria and responsible for the secretion of multiple substrates