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pro vyhledávání: '"Robert Zhong"'
Akademický článek
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Autor:
Luo Chen, Wai Yin Chau, Hei Tung Yuen, Xiao Han Liu, Robert Zhong Qi, Maria Li Lung, Hong Lok Lung
Publikováno v:
Cancers; Volume 15; Issue 7; Pages: 2189
We had previously shown that THY1 (CD90) is a tumor suppressor in nasopharyngeal carcinoma (NPC) and that its down-regulation and loss of expression are associated with tumor metastasis, yet the mechanism leading to such effects remains unknown. In t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40ec9d96fc9e2d9456209e0bfd548be4
https://doi.org/10.3390/cancers15072189
https://doi.org/10.3390/cancers15072189
Publikováno v:
American Journal of Transplantation. 8:1143-1150
Two previous reports that receptor-interacting protein (RIP)-2 knockout (RIP2-/-) mice had defective nuclear factor-kappa B (NF-kappaB) signaling and T helper (Th)1 immune responses had led us to believe that this putative serine-threonine kinase mig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93073b061be3d06f6bc8c8f1453347c1
https://doi.org/10.1111/j.1600-6143.2008.02236.x
https://doi.org/10.1111/j.1600-6143.2008.02236.x
Autor:
Wei-Ping Min, Costin Vladau, Hongtao Sun, Dameng Lian, Zhu-Xu Zhang, Mu Li, Bertha Garcia, Xiaoping Xia, Xuyan Huang, Motohiko Suzuki, Xusheng Zhang, Xiufen Zheng, Robert Zhong
Publikováno v:
International Immunology. 20:285-293
Dendritic cells are among the most potent antigen-presenting cells and are important in the development of both immunity and tolerance. Tolerogenic dendritic cell (Tol-DC) is a key factor in the induction and maintenance of tolerance during transplan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::284259abe1114111c28fd5fbfda6bd94
https://doi.org/10.1093/intimm/dxm142
https://doi.org/10.1093/intimm/dxm142
Autor:
Yuexia Ma, Zhu-Xu Zhang, Shuang Wang, Anthony M. Jevnikar, Wei-Ping Min, Robert Zhong, Kathy M. He
Publikováno v:
European Journal of Immunology. 37:3455-3466
Bone marrow (BM) transplantation is an efficient approach to develop donor-specific tolerance and prevent chronic rejection. Allogeneic BM transplantation is limited by donor T cell-mediated graft-versus-host disease, requirement of cytoreduction and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a18b4652c91270f70267c58ef8f66b5
https://doi.org/10.1002/eji.200737408
https://doi.org/10.1002/eji.200737408
Autor:
Bertha Garcia, Robert Zhong, J. Arp, Siobhan Ramcharran, Jifu Jiang, Hao Wang, Russell P. Rother, David Gies, Susan J. Faas, Weihua Liu
Publikováno v:
The Journal of Immunology. 179:4451-4463
Ab-mediated rejection (AMR) remains the primary obstacle in presensitized patients following organ transplantation, as it is refractory to anti-T cell therapy and can lead to early graft loss. Complement plays an important role in the process of AMR.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24948f387866eef618fa3020a19fa190
https://doi.org/10.4049/jimmunol.179.7.4451
https://doi.org/10.4049/jimmunol.179.7.4451
Autor:
Hong Diao, Shuang Wang, Dameng Lian, Caigan Du, Qiunong Guan, Anthony M. Jevnikar, Robert Zhong
Publikováno v:
Transplantation. 83:323-332
BACKGROUND It has been demonstrated that in vitro the presence of extracellular signal-regulated kinase 1 and 2 (ERK1/2) signaling inhibitor suppresses T cell activation and Th1 development. However, pharmacological interference of ERK1/2 signaling b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f850f55b9fa5bfbb8498c0726cb75bfb
https://doi.org/10.1097/01.tp.0000251374.49225.19
https://doi.org/10.1097/01.tp.0000251374.49225.19
Autor:
Patrick P. Luke, Hua Qian, W. Liu, Ying Xiang, A. M. Jevnikar, Lydia Visser, Hongtao Sun, Sibrand Poppema, Hao Wang, Annemarie Schneider, G. Senaldi, Gang Chen, H. Yang, Bertha Garcia, Robert Zhong, Xuyan Huang
Publikováno v:
American Journal of Transplantation, 7(1), 27-37. Wiley
Previously, an anti-CD45RB monoclonal antibody (mAb) has been shown to induce murine allograft tolerance. The present study was performed to assess the ability of an anti-human CD45RB mAb to prevent rejection in a monkey MHC-mismatched kidney transpl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47a79e61ebed0598f3d068f087dd9715
https://doi.org/10.1111/j.1600-6143.2006.01598.x
https://doi.org/10.1111/j.1600-6143.2006.01598.x
Publikováno v:
American Journal of Transplantation. 6:2256-2267
Renal tubular epithelial cells (TEC) die by apoptosis or necrosis in renal ischemia-reperfusion injury (IRI). Fas/Fas ligand-dependent fratricide is critical in TEC apoptosis, and Fas promotes renal IRI. Therefore, targeting Fas or caspase-8 may have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b1b072770056e8d818d991fd0e58b06
https://doi.org/10.1111/j.1600-6143.2006.01478.x
https://doi.org/10.1111/j.1600-6143.2006.01478.x
Autor:
R. Liu, Costin Vladau, Bertha Garcia, W. Liu, Robert Zhong, Hongtao Sun, Gang Chen, Xizhong Zhang, Xiufen Zheng, Wei-Ping Min, Anthony M. Jevnikar, Mu Li, Biao Feng
Publikováno v:
American Journal of Transplantation. 6:2099-2108
The complement system is one of the important mediators of renal ischemia-reperfusion injury (IRI). We hypothesized that efficient silencing of C3, which is the central component on which all complement activation pathways converge, could be achieved
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e30974a427980164c71b5b1093aeff0
https://doi.org/10.1111/j.1600-6143.2006.01427.x
https://doi.org/10.1111/j.1600-6143.2006.01427.x