Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Robert Z. Maigetter"'
Autor:
Dennis J. Carlo, Richard S. Gore, Peter Lowry, H.R. Tian, Richard J. Trauger, Robert Z. Maigetter, Fred C. Jensen, Christopher P. Prior, Richard M. Bartholomew, Jay R. Savary, Steven P. Richieri, Roy Musil, J. Holt, Francois Ferre, Roland C. Aloia
Publikováno v:
Vaccine. 16:119-129
This report characterizes inactivated, gp120 depleted, HIV-1 particles purified by an anion exchange chromatography production process. This antigen formulated with incomplete Freund's adjuvant constitutes Remune, which is being evaluated in a phase
Autor:
Claudio Thomasin, Tom Piombino, Christian Wood, Bryan Shingle, David Clark, Tom Gervais, Robert Z. Maigetter, Dave A. Wareheim
Publikováno v:
Encyclopedia of Industrial Biotechnology
This chapter will focus on the opportunities for SU systems and their acceptance into bioprocess facilities building new or retrofitting with 100% SU. The first section of the chapter will examine the more traditional stainless steel bioreactors and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19b9e2eedb9f9ea429449f703790ca95
https://doi.org/10.1002/9780470054581.eib116
https://doi.org/10.1002/9780470054581.eib116
Autor:
Robert Z. Maigetter, David C. Heimbrook, Denis R. Patrick, G R Vuocolo, Deborah Defeo-Jones, Oliff Allen I, K Zhang, Mohinder K. Sardana
Publikováno v:
Journal of Biological Chemistry. 267:6910-6915
Human papillomaviruses (HPVs) are the etiologic agents responsible for genital warts and are contributing factors in the pathogenesis of human cervical cancer. The HPV E7 gene is transcriptionally active in these diseases and has been shown to transf
Autor:
Oliff Allen I, Gwynneth M. Edwards, Robert Z. Maigetter, Hans E. Huber, David C. Heimbrook, Deborah Defeo-Jones, Gautam Sanyal, G A Vuocolo, P J Goodhart
Publikováno v:
Journal of Biological Chemistry. 267:7971-7974
The retinoblastoma susceptibility gene (RB) encodes a 928-amino acid protein (pRB) that is hypothesized to function in a pathway that restricts cell proliferation. The immortalizing proteins from three distinct DNA tumor viruses (SV40 large T antigen
Autor:
David C. Heimbrook, Robert Z. Maigetter, Martha H. Marshall, Wayne K. Herbert, Steven M. Stirdivant, Daniel D. Von Hoff, Oliff Allen I, Janet D. Ahern
Publikováno v:
Investigational New Drugs. 10:17-22
Transforming growth factor-alpha-Pseudomonas exotoxin-40 (TP40) is a recombinant fusion protein. TP40 consists of the entire human transforming growth factor-alpha (TGF alpha) protein fused to a 40,000 Da. segment of the Pseudomonas exotoxin A protei
Publikováno v:
Applied Microbiology and Biotechnology. 36:149-152
Two fermentation processes for the tryptophan-regulated expression of active HIV protease (HIV-1 prt) in Escherichia coli are described. Since overexpression of HIV-1 prt results in cell death, stringent control of product expression was necessary to
Publikováno v:
Journal of Biotechnology. 21:109-125
A high-cell density bioprocess has been developed for the production of hepatitis B surface protein (preS2 + S) by recombinant yeast. This fed-batch process utilizes a growth medium containing yeast extract, soy peptone and glucose which was fed at a
Publikováno v:
Enzyme and Microbial Technology. 12:647-652
A contained, crossflow filtration (CFF) membrane system is described for harvesting Saccharomyces cerevisiae and Escherichia coli cells. This system is portable and can be cleaned and sanitized in place. Low- and high-cell density (LCD, HCD) fermenta
Autor:
Steven Rosenberg, Patricia Tekamp-Olson, William J. McAleer, Robert Z. Maigetter, Christine E. Carty
Publikováno v:
Biotechnology Letters. 11:301-306
A yeast expressing the hepatitis B surface antigen (HBsAg) gene under the control of a regulated promoter was grown in batch and fed-batch modes. In batch fermentations, the addition of galactose caused the rapid production of HBsAg. Cells grown in f
Autor:
Robert Z. Maigetter, Guadalupe A. Limjuco, Johanna Y. Zeltner, Dennis J. Carlo, Yashwant D. Karkhanis, J. J. King
Publikováno v:
Journal of General Microbiology. 104:187-191
SUMMARY: A lipopolysaccharide was isolated from Neisseria meningitidis group B by phenol/water extraction and purified by differential ultracentrifugation. This preparation exhibited endotoxic properties as shown by the limulus-lysate assay. Mild aci