Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Robert Y Igarashi"'
Autor:
Pedro Romero, Andre Kunert, Hardikkumar Jetani, Katarzyna Franciszkiewicz, David Vlerick, Aleksandra Nowicka, Robert Y Igarashi
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/7490abba5edc40e48765b49046654d54
Autor:
Jeremiah L. Oyer, Tayler J. Croom-Perez, Md Faqrul Hasan, Javier A. Rivera-Huertas, Sarah B. Gitto, Joanna M. Mucha, Xiang Zhu, Deborah A. Altomare, Robert Y. Igarashi, Alicja J. Copik
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
NK cell therapeutics have gained significant attention as a potential cancer treatment. Towards therapeutic use, NK cells need to be activated and expanded to attain high potency and large quantities for an effective dosage. This is typically done by
Externí odkaz:
https://doaj.org/article/a1322c48c6044a24a3fa333918436d9b
Autor:
Marco Meloni, Pauline Perrin, Erik Slinger, Chrissta Maracle, Alain Fournier, Nicole Acuff, Jill Mooney, Robert Y. Igarashi, Angela Virone-Oddos, Marielle Chiron
Publikováno v:
Cancer Research. 82:4209-4209
Multiple myeloma (MM) is a plasma cell malignancy characterized by clonal accumulation of malignant plasma cells in the bone marrow. CD38 is highly expressed on MM cells, and antibodies targeting CD38 (such as Isatuximab and Daratumumab) induce MM ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38c7106cdec81ad6f87d5ce4fd8fe7b9
https://doi.org/10.1158/1538-7445.am2022-4209
https://doi.org/10.1158/1538-7445.am2022-4209
Autor:
Jeremiah Oyer, Anne Showalter, Robert Y. Igarashi, Annette R. Khaled, Christina Kittipatarin, Alicja J. Copik, Arati Limaye
Publikováno v:
Cytokine. 97:123-132
Despite advances in treatments like chemotherapy and radiotherapy, metastatic cancer remains a leading cause of death for cancer patients. While many chemotherapeutic agents can efficiently eliminate cancer cells, long-term protection against cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83dedff9cebbf98634fa1df9de149fa4
https://doi.org/10.1016/j.cyto.2017.05.024
https://doi.org/10.1016/j.cyto.2017.05.024
Autor:
Alicja J. Copik, Veethika Pandey, Deborah A. Altomare, Robert Y. Igarashi, Sarah B. Gitto, Jeremiah Oyer
Publikováno v:
Oncotarget
Treatment of ovarian cancer, a leading cause of gynecological malignancy, has good initial efficacy with surgery and platinum/taxane-based chemotherapy, but poor long-term survival in patients. Inferior long-term prognosis is attributed to intraperit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59cbe680aa88dabdd8262a3656257049
http://europepmc.org/articles/PMC4872788
http://europepmc.org/articles/PMC4872788
Autor:
Jeremiah Oyer, Deborah A. Altomare, Robert Y. Igarashi, J.M. Mucha, Alicja J. Copik, Dean A. Lee
Publikováno v:
Cytotherapy. 22:S123
Background & Aim Natural Killer (NK) cells are innate cytotoxic lymphocytes with high potential for development of cell-based anti-cancer therapeutics. To be applied clinically, NK cells need to be expanded to achieve sufficient amounts for therapeut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bfafb110b8159a040c2cdbd24b552f66
https://doi.org/10.1016/j.jcyt.2020.03.231
https://doi.org/10.1016/j.jcyt.2020.03.231
Autor:
Alicja J. Copik, Yasser Khaled, Deborah A. Altomare, Robert Y. Igarashi, Alexander R. Kulikowski, Melhem Solh, Dominic A. Colosimo, Jeremiah Oyer, Ahmed Zakari
Publikováno v:
Biology of Blood and Marrow Transplantation. 21:632-639
Natural killer (NK) cell immunotherapy as a cancer treatment shows promise, but expanding NK cells consistently from a small fraction (∼5%) of peripheral blood mononuclear cells (PBMCs) to therapeutic amounts remains challenging. Most current ex vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::379ed46ac1d74d0b1a2f8a2783e11cfc
https://doi.org/10.1016/j.bbmt.2014.12.037
https://doi.org/10.1016/j.bbmt.2014.12.037
Autor:
Deborah Altamore, Nitin Chakravarti, Alicja J. Copik, Dean A. Lee, Robert Y. Igarashi, Jeremiah Oyer
Publikováno v:
Blood. 134:3598-3598
Introduction Therapy of marrow borne disease such as leukemias or myelomas require the eradication of tumor cells that are resident in the bone marrow. Cell based therapies are increasingly a promising modality toward potential complete cures of such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1b2a49e25e0fd624e4cf7d523e2fa09
https://doi.org/10.1182/blood-2019-131137
https://doi.org/10.1182/blood-2019-131137
Autor:
Lynn M. Sims, Robert Y. Igarashi
Publikováno v:
Archives of Biochemistry and Biophysics. 524:114-122
Ribosomal function is dependent on multiple proteins. The ABCE1 ATPase, a unique ABC superfamily member that bears two Fe 4 S 4 clusters, is crucial for ribosomal biogenesis and recycling. Here, the ATPase activity of the Pyrococcus abyssi ABCE1 ( Pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca84d70de6097ead5b2d962eb80da49c
https://doi.org/10.1016/j.abb.2012.05.004
https://doi.org/10.1016/j.abb.2012.05.004
Autor:
Brian M. Hoffman, Joshua Telser, Brett M. Barney, Peter E. Doan, Lance C. Seefeldt, Robert Y. Igarashi, Dennis R. Dean
Publikováno v:
Journal of the American Chemical Society. 133:17329-17340
N(2) binds to the active-site metal cluster in the nitrogenase MoFe protein, the FeMo-cofactor ([7Fe-9S-Mo-homocitrate-X]; FeMo-co) only after the MoFe protein has accumulated three or four electrons/protons (E(3) or E(4) states), with the E(4) state
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baff4eabb30541c29356ab88a2ebb721
https://doi.org/10.1021/ja205304t
https://doi.org/10.1021/ja205304t