Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Robert William Welke"'
Autor:
Robert-William Welke, Hannah Sabeth Sperber, Ronny Bergmann, Amit Koikkarah, Laura Menke, Christian Sieben, Detlev H. Krüger, Salvatore Chiantia, Andreas Herrmann, Roland Schwarzer
Publikováno v:
Viruses, Vol 14, Iss 3, p 457 (2022)
Hantaviruses are enveloped viruses that possess a tri-segmented, negative-sense RNA genome. The viral S-segment encodes the multifunctional nucleocapsid protein (N), which is involved in genome packaging, intracellular protein transport, immunoregula
Externí odkaz:
https://doaj.org/article/e3d399b345e347d190ea0b523cd2c36a
Autor:
Markus Lesch, Madlen Luckner, Michael Meyer, Friderike Weege, Isabella Gravenstein, Martin Raftery, Christian Sieben, Laura Martin-Sancho, Aki Imai-Matsushima, Robert-William Welke, Rebecca Frise, Wendy Barclay, Günther Schönrich, Andreas Herrmann, Thomas F Meyer, Alexander Karlas
Publikováno v:
PLoS Pathogens, Vol 15, Iss 3, p e1007601 (2019)
Influenza viruses (IVs) tend to rapidly develop resistance to virus-directed vaccines and common antivirals targeting pathogen determinants, but novel host-directed approaches might preclude resistance development. To identify the most promising cell
Externí odkaz:
https://doaj.org/article/ca482f1640084693b48f8127b5cc6bdc
Autor:
Max Schelker, Caroline Maria Mair, Fabian Jolmes, Robert-William Welke, Edda Klipp, Andreas Herrmann, Max Flöttmann, Christian Sieben
Publikováno v:
PLoS Computational Biology, Vol 12, Iss 10, p e1005075 (2016)
After endocytic uptake, influenza viruses transit early endosomal compartments and eventually reach late endosomes. There, the viral glycoprotein hemagglutinin (HA) triggers fusion between endosomal and viral membrane, a critical step that leads to r
Externí odkaz:
https://doaj.org/article/602d7560243d42a5afa2d5686a9516bf
Autor:
Lennart Brandenburg, Philipp Mertins, Kiara Freitag, Jakobus van Unen, Vivian Nguyen, Celina Wortmann, Paul Markus Mueller, Oliver Popp, Trendelina Rrustemi, Oliver Rocks, Lisa Spatt, Brett Larsen, Juliane Rademacher, Tony Pawson, Richard D. Bagshaw, Patricia Pascual-Vargas, Rebecca L Eccles, Olivier Pertz, Maciej T. Czajkowski, Carolin Barth, Evangelia Petsalaki, Monika Tucholska, Robert William Welke, Sunqu Zhang, Philipp Trnka, Geraldine Mbamalu, Louise E Heinrich, Anne-Claude Gingras, Marta Sanchez-Castro, Karen Colwill, Frederick P. Roth, Girolamo Giudice, Keziban M. Alp, Chris Bakal
Publikováno v:
Nature Cell Biology. 22:498-511
Rho GTPases are central regulators of the cytoskeleton and, in humans, are controlled by 145 multidomain guanine nucleotide exchange factors (RhoGEFs) and GTPase-activating proteins (RhoGAPs). How Rho signalling patterns are established in dynamic ce
Autor:
Michael Meyer, Wendy S. Barclay, Aki Imai-Matsushima, Markus Lesch, Laura Martin-Sancho, Thomas F. Meyer, Isabella Gravenstein, Martin Raftery, Günther Schönrich, Andreas Herrmann, Friderike Weege, Robert-William Welke, Madlen Luckner, Alexander Karlas, Christian Sieben, Rebecca Frise
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 15, Iss 3, p e1007601 (2019)
PLoS Pathogens, Vol 15, Iss 3, p e1007601 (2019)
Influenza viruses (IVs) tend to rapidly develop resistance to virus-directed vaccines and common antivirals targeting pathogen determinants, but novel host-directed approaches might preclude resistance development. To identify the most promising cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::428a8e553216971f27c2f0b13895705f
https://hdl.handle.net/21.11116/0000-0003-8009-221.11116/0000-0003-800B-0
https://hdl.handle.net/21.11116/0000-0003-8009-221.11116/0000-0003-800B-0
Autor:
Roland Schwarzer, Andreas Herrmann, Hannah Sabeth Sperber, Ronny Bergmann, Matthias Schade, Roberto Arturo Petazzi, Salvatore Chiantia, Yechiel Shai, Robert-William Welke
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-15 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-15 (2019)
Hantavirus assembly and budding are governed by the surface glycoproteins Gn and Gc. In this study, we investigated the glycoproteins of Puumala, the most abundant Hantavirus species in Europe, using fluorescently labeled wild-type constructs and cyt
Autor:
Andreas Herrmann, Max Flöttmann, Christian Sieben, Edda Klipp, Fabian Jolmes, Max Schelker, Robert-William Welke, Caroline M. Mair
Publikováno v:
PLoS Computational Biology, Vol 12, Iss 10, p e1005075 (2016)
PLoS Computational Biology
PLoS Computational Biology
After endocytic uptake, influenza viruses transit early endosomal compartments and eventually reach late endosomes. There, the viral glycoprotein hemagglutinin (HA) triggers fusion between endosomal and viral membrane, a critical step that leads to r
Autor:
Andreas Geissner, Alexander Karlas, Konstantin Okonechnikov, Peter H. Seeberger, Markus Lesch, Thomas F. Meyer, Markus Kastner, Mirshat Abdurishid, Christian Sieben, Chakkumkal Anish, Robert-William Welke, Rong Zhu, Peter Hinterdorfer, Volker Brinkmann, Andreas Herrmann, Xenia Wörmann, Andreas Karner
Publikováno v:
Virology
The 2009 influenza pandemic originated from a swine-origin H1N1 virus, which, although less pathogenic than anticipated, may acquire additional virulence-associated mutations in the future. To estimate the potential risk, we sequentially passaged the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd2a89ec26b198aeca6a0ed8a9282706
https://hdl.handle.net/11858/00-001M-0000-002A-5148-C11858/00-001M-0000-002A-5146-021.11116/0000-0005-60B6-1
https://hdl.handle.net/11858/00-001M-0000-002A-5148-C11858/00-001M-0000-002A-5146-021.11116/0000-0005-60B6-1
Autor:
Waltho, Anita, Popp, Oliver, Lenz, Christopher, Pluska, Lukas, Lambert, Mahil, Dötsch, Volker, Mertins, Philipp, Sommer, Thomas
Publikováno v:
Life Science Alliance; Aug2024, Vol. 7 Issue 8, p1-18, 18p
Autor:
Welke, Robert-William1 (AUTHOR) robert-william.welke@gmx.de, Sperber, Hannah Sabeth2 (AUTHOR) hannahsperber.7@googlemail.com, Bergmann, Ronny1 (AUTHOR) ronny.bergmann91@gmail.com, Koikkarah, Amit3 (AUTHOR) amitkoikkarah93@gmail.com, Menke, Laura4 (AUTHOR) laura.menke@helmholtz-hzi.de, Sieben, Christian4,5 (AUTHOR) christian.sieben@helmholtz-hzi.de, Krüger, Detlev H.6 (AUTHOR) detlev.krueger@charite.de, Chiantia, Salvatore3 (AUTHOR) chiantia@uni-potsdam.de, Herrmann, Andreas1,7 (AUTHOR) andreas.herrmann@rz.hu-berlin.de, Schwarzer, Roland2 (AUTHOR) roland-schwarzer@gmx.de
Publikováno v:
Viruses (1999-4915). Mar2022, Vol. 14 Issue 3, p457-457. 14p.